Brief Article
Copyright ©2010 Baishideng. All rights reserved.
World J Gastroenterol. Jul 28, 2010; 16(28): 3553-3560
Published online Jul 28, 2010. doi: 10.3748/wjg.v16.i28.3553
Promoter methylation status of hMLH1, MGMT, and CDKN2A/p16 in colorectal adenomas
Vasiliki Psofaki, Chryssoula Kalogera, Nikolaos Tzambouras, Dimitrios Stephanou, Epameinondas Tsianos, Konstantin Seferiadis, Georgios Kolios
Vasiliki Psofaki, Laboratory of Clinical Chemistry, University of Ioannina Medical School, 45500 Ioannina, Greece
Chryssoula Kalogera, Konstantin Seferiadis, Georgios Kolios, Laboratory of Biochemistry, University Hospital of Ioannina, Leoforos S. Niarchou, 45500 Ioannina, Greece
Nikolaos Tzambouras, Epameinondas Tsianos, Hepatogastroenterology Unit of Internal Medicine, University Hospital of Ioannina, Leoforos S. Niarchou, 45500 Ioannina, Greece
Dimitrios Stephanou, Laboratory of Pathology, University Hospital of Ioannina, Leoforos S. Niarchou, 45500 Ioannina, Greece
Author contributions: All authors actively participated in the study and read the manuscript; Psofaki V performed the molecular analysis and contributed to the study design, data collection, data analysis, and manuscript writing; Kalogera C participated in planning, design and executing of the study, review, and finalization of the manuscript; Tzambouras N performed the colonoscopies and participated in data collection and interpretation of the histopathological analysis; Stephanou D performed the histopathological analysis and contributed to data collection and interpretation of the results; Tsianos E contributed to data interpretation and final review of the manuscript; Seferiadis K contributed to planning of the study, data interpretation, and final review of the manuscript; Kolios G was the principal investigator of the grant and was responsible for the study design, execution, data management and analysis, as well as manuscript preparation.
Supported by A 2-year grant of the Greek Ministry of Health and Welfare, No. 111K/56
Correspondence to: Georgios Kolios, PhD, Laboratory of Biochemistry, University Hospital of Ioannina, Leoforos S. Niarchou, 45500 Ioannina, Greece. gkolios@uhi.gr
Telephone: +30-26510-99419 Fax: +30-26510-99418
Received: December 19, 2009
Revised: February 3, 2010
Accepted: February 10, 2010
Published online: July 28, 2010
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