Nardostachys jatamansi extract protects against cytokine-induced &beta;-cell damage and streptozotocin-induced diabetes

doi:10.3748/wjg.v16.i26.3249

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 14, 2010; 16(26): 3249-3257
Published online Jul 14, 2010. doi: 10.3748/wjg.v16.i26.3249

Nardostachys jatamansi extract protects against cytokine-induced β-cell damage and streptozotocin-induced diabetes

Mi-Young Song, Ui-Jin Bae, Bong-Hee Lee, Kang-Beom Kwon, Eun-A Seo, Sung-Joo Park, Min-Sun Kim, Ho-Joon Song, Keun-Sang Kwon, Jin-Woo Park, Do-Gon Ryu, Byung-Hyun Park

Mi-Young Song, Jin-Woo Park, Byung-Hyun Park, Department of Biochemistry, Medical School and Diabetes Research Center, Chonbuk National University, Jeonju, Jeonbuk 561-756, South Korea

Ui-Jin Bae, Bong-Hee Lee, Kang-Beom Kwon, Do-Gon Ryu, Department of Physiology, School of Oriental Medicine, Wonkwang University, Iksan, Jeonbuk 570-749, South Korea

Eun-A Seo, Department of Food and Nutrition, School of Human Environmental Science, Wonkwang University, Iksan, Jeonbuk 570-749, South Korea

Sung-Joo Park, Min-Sun Kim, Ho-Joon Song, Department of Herbology, School of Oriental Medicine, Wonkwang University, Iksan, Jeonbuk 570-749, South Korea

Keun-Sang Kwon, Department of Preventive Medicine, Medical School, Chonbuk National University, Jeonju, Jeonbuk 561-756, South Korea

Author contributions: Song MY and Bae UJ contributed equally to this work; Song MY and Bae UJ performed the research; Kwon KB, Seo EA and Park JW designed the research; Park SJ, Kim MS and Song HJ prepared Nardostachys jatamansi extract; Lee BH performed the research; Kwon KS analyzed the data; Ryu DG and Park BH wrote the paper.

Supported by Grant from the Ministry of Science and Technology/Korea Science and Engineering Foundation through the Diabetes Research Center at Chonbuk National University, R13-2008-005-0000-0, and by a Research Fund of Chonbuk National University in 2009 (to Park BH)

Correspondence to: Byung-Hyun Park, MD, PhD, Department of Biochemistry, Medical School and Diabetes Research Center, Chonbuk National University, Jeonju, Jeonbuk 561-756, South Korea. bhpark@jbnu.ac.kr

Telephone: +82-63-2703139 Fax: +82-63-2749833

Received: February 3, 2010
Revised: March 17, 2010
Accepted: March 24, 2010
Published online: July 14, 2010

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