Original Article
Copyright ©2010 Baishideng. All rights reserved
World J Gastroenterol. May 14, 2010; 16(18): 2235-2243
Published online May 14, 2010. doi: 10.3748/wjg.v16.i18.2235
Apoptotic activity of caged xanthones from Garcinia hanburyi in cholangiocarcinoma cell lines
Chariya Hahnvajanawong, Wongwarut Boonyanugomol, Tapanawan Nasomyon, Watcharin Loilome, Nisana Namwat, Natthinee Anantachoke, Wichittra Tassaneeyakul, Banchob Sripa, Wises Namwat, Vichai Reutrakul
Chariya Hahnvajanawong, Wongwarut Boonyanugomol, Tapanawan Nasomyon, Wises Namwat, Department of Microbiology, Center of Excellence for Innovation in Chemistry, and Liver Fluke and Cholangiocarcinoma Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
Watcharin Loilome, Nisana Namwat, Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
Natthinee Anantachoke, Department of Pharmacognosy, Faculty of Pharmacy, Mahidol University, Bangkok 10400, Thailand
Wichittra Tassaneeyakul, Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
Banchob Sripa, Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
Vichai Reutrakul, Department of Chemistry, and Center of Excellence for Innovation in Chemistry, Faculty of Science, Mahidol University, Bangkok 10400, Thailand
Author contributions: Hahnvajanawong C designed the research; Hahnvajanawong C, Boonyanugomol W, Nasomyon T, Namwat W, Loilome W, Namwat N, Tassaneeyakul W and Sripa B performed the research; Reutrakul V and Anantachoke N purified all caged xanthones; Hahnvajanawong C, Boonyanugomol W and Nasomyon T analyzed the data; Reutrakul V and Hahnvajanawong C wrote the paper.
Supported by Grants from the Center of Excellence for Innovation in Chemistry, Commission on Higher Education, No. 48-03-3-00-144; Faculty of Medicine, No. 51-03-2-00-008 and Khon Kaen University, No. 50-03-1-01-005, Research Funds, Khon Kaen University, Thailand
Correspondence to: Vichai Reutrakul, PhD, Professor, Department of Chemistry, Faculty of Sciences, Mahidol University, 272 Rama 6 Road, Bangkok 10400, Thailand. scvrt@mahidol.ac.th
Telephone: +66-2-2015152 Fax: +66-2-6445126
Received: November 18, 2009
Revised: January 8, 2010
Accepted: January 15, 2010
Published online: May 14, 2010
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