Short-chain fatty acids act as antiinflammatory mediators by regulating prostaglandin E2 and cytokines

doi:10.3748/wjg.15.5549

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Nov 28, 2009 (publication date) through Apr 15, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 28, 2009; 15(44): 5549-5557
Published online Nov 28, 2009. doi: 10.3748/wjg.15.5549

Short-chain fatty acids act as antiinflammatory mediators by regulating prostaglandin E₂ and cytokines

Mary Ann Cox, James Jackson, Michaela Stanton, Alberto Rojas-Triana, Loretta Bober, Maureen Laverty, Xiaoxin Yang, Feng Zhu, Jianjun Liu, Suke Wang, Frederick Monsma, Galya Vassileva, Maureen Maguire, Eric Gustafson, Marvin Bayne, Chuan-Chu Chou, Daniel Lundell, Chung-Her Jenh

Mary Ann Cox, Department of Tumor Biology, Schering-Plough Research Institute, Kenilworth, NJ 07033, United States

James Jackson, Michaela Stanton, Alberto Rojas-Triana, Loretta Bober, Marvin Bayne, Chuan-Chu Chou, Chung-Her Jenh, Department of Cardiovascular and Metabolic Disease Research, Schering-Plough Research Institute, Kenilworth, NJ 07033, United States

Maureen Laverty, Xiaoxin Yang, Feng Zhu, Jianjun Liu, Suke Wang, Frederick Monsma, Galya Vassileva, Maureen Maguire, Eric Gustafson, Department of Discovery Technologies, Schering-Plough Research Institute, Kenilworth, NJ 07033, United States

Marvin Bayne, Department of Discovery Technologies, Schering-Plough Research Institute, Kenilworth, NJ 07033, United States

Daniel Lundell, Department of Inflammation, Schering-Plough Research Institute, Kenilworth, NJ 07033, United States

Author contributions: Cox MA, Jackson J, Stanton M, Rojas-Triana A, Laverty M, Yang X, Zhu F, Liu J and Maguire M performed the research; Cox MA, Bober L, Wang S, Monsma F, Vassileva G, Gustafson E and Jenh CH designed the research; Bayne M, Chou CC and Lundell D provided support and critical reading; Bober L contributed to the writing and discussion; Jenh CH coordinated the research and wrote the manuscript.

Correspondence to: Dr. Chung-Her Jenh, Department of Cardiovascular and Metabolic Disease Research, Schering-Plough Research Institute, K-15-1600, 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States. chung-her.jenh@spcorp.com

Telephone: +1-908-7403072 Fax: +1-908-7407115

Received: August 14, 2009
Revised: September 12, 2009
Accepted: September 19, 2009
Published online: November 28, 2009

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