Basic Research
Copyright ©2008 The WJG Press and Baishideng. All rights reserved.
World J Gastroenterol. Oct 14, 2008; 14(38): 5842-5850
Published online Oct 14, 2008. doi: 10.3748/wjg.14.5842
Therapy with bone marrow cells reduces liver alterations in mice chronically infected by Schistosoma mansoni
Sheilla Andrade Oliveira, Bruno Solano Freitas Souza, Carla Adriana Guimarães-Ferreira, Elton Sá Barreto, Siane Campos Souza, Luiz Antonio Rodrigues Freitas, Ricardo Ribeiro-dos-Santos, Milena Botelho Pereira Soares
Sheilla Andrade Oliveira, Centro de Pesquisas Gonçalo Moniz, Fundação Oswaldo Cruz, Rua Waldemar Falcão 121, Brotas, 40295-001 Salvador, BA, Brazil and Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz, Recife, Av Moraes Rego s/n, Cidade Universitária, Recife 50670-420, PE, Brazil
Bruno Solano Freitas Souza, Carla Adriana Guimarães-Ferreira, Elton Sá Barreto, Siane Campos Souza, Luiz Antonio Rodrigues Freitas, Centro de Pesquisas Gonçalo Moniz, Fundação Oswaldo Cruz, Rua Waldemar Falcão 121, Brotas, Salvador 40295-001, BA, Brazil
Ricardo Ribeiro-dos-Santos, Milena Botelho Pereira Soares, Centro de Pesquisas Gonçalo Moniz, Fundação Oswaldo Cruz, Rua Waldemar Falcão 121, Brotas, 40295-001 Salvador, BA, Brazil and Hospital São Rafael, Av São Rafael, 2152, São Marcos, Salvador 41256-900, BA, Brazil
Author contributions: Oliveira SA designed, conducted the study and analyzed the data; Souza BSF and Barreto ES conducted the morphometric and immunofluorescence studies; Guimarães-Ferreira CA and Souza SC performed FISH and PCR analyses; Freitas LAR performed the histopathological analyses; Ribeiro-dos-Santos R and Soares MBP were involved in designing the study, reviewing and interpreting the results. All authors were involved in drafting the manuscript.
Supported by Instituto do Milênio de Bioengenharia Tecidual (IMBT, CNPq/MCT), Rede Nordeste de Biotecnologia (RENORBIO, FINEP/MCT), Fundação de Amparo à Pesquisa do Estado da Bahia (FAPESB) and Fundação Oswaldo Cruz (FIOCRUZ)
Correspondence to: Milena Botelho Pereira Soares, PhD, Centro de Pesquisas Gonçalo Moniz, Fundação Oswaldo Cruz, Rua Waldemar Falcão 121, Brotas, Salvador 40295-001, BA, Brazil. milena@bahia.fiocruz.br
Telephone: +55-71-31762260 Fax: +55-71-31762292
Received: July 8, 2008
Revised: August 21, 2008
Accepted: August 28, 2008
Published online: October 14, 2008
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