Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 21, 2023; 29(27): 4356-4367
Published online Jul 21, 2023. doi: 10.3748/wjg.v29.i27.4356
Research landscape on COVID-19 and liver dysfunction: A bibliometric analysis
Sa'ed H Zyoud
Sa'ed H Zyoud, Department of Clinical and Community Pharmacy, College of Medicine and Health Sciences, An-Najah National University, Nablus 44839, Palestine
Sa'ed H Zyoud, Poison Control and Drug Information Center (PCDIC), College of Medicine and Health Sciences, An-Najah National University, Nablus 44839, Palestine
Sa'ed H Zyoud, Clinical Research Centre, An-Najah National University Hospital, Nablus 44839, Palestine
Author contributions: Zyoud S developed the concept for the manuscript, reviewed the literature, formulated research questions, collected the data, conducted analyses and interpreted the data, and wrote the manuscript; Zyoud S read and approved the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Sa'ed H Zyoud, PhD, Full Professor, Department of Clinical and Community Pharmacy, College of Medicine and Health Sciences, An-Najah National University, Academic Street, Nablus 44839, Palestine.
Received: February 24, 2023
Peer-review started: February 24, 2023
First decision: May 23, 2023
Revised: June 16, 2023
Accepted: June 27, 2023
Article in press: June 27, 2023
Published online: July 21, 2023
Research background

Abnormal liver chemistry findings are commonly observed in individuals with coronavirus disease 2019 (COVID-19). As a result, there is a significant body of literature comprising published clinical studies that specifically examine the implications of hepatic involvement in COVID-19.

Research motivation

Understanding the current state of research and hotspots in the field of COVID-19 and liver dysfunction is crucial for identifying knowledge gaps and informing future research directions.

Research objectives

The purpose of this study is to present a comprehensive overview of the existing research on COVID-19 and liver dysfunction through the utilization of bibliometric analysis.

Research methods

A thorough and validated search query was conducted using the SciVerse Scopus database to identify relevant publications on the topic of COVID-19 and liver dysfunction. Subsequently, the research hotspots in related fields were examined using VOSviewer software.

Research results

Three distinct clusters of topics were identified: COVID-19 vaccines in liver transplant recipients, liver function tests as predictors of severity and clinical outcomes in hospitalized patients, and the care of patients with liver disease during the COVID-19 pandemic.

Research conclusions

The first bibliometric analysis is presented here, which is represented by the study and offers valuable insights into the research landscape on COVID-19 and liver dysfunction. Valuable reference can be derived from the findings in this field by scholars, as a comprehensive summary is provided and the frontiers of research related to COVID-19 and liver dysfunction are identified.

Research perspectives

The goal of this study is to have current areas of focus within the field of COVID-19 and liver dysfunction identified, which can help future research be guided and clinical practice be informed. By using bibliometric analysis, a comprehensive overview of the literature on this topic is provided by the study, and the latest developments in the field can be kept up-to-date by researchers and clinicians.