Case Control Study
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Oct 21, 2020; 26(39): 6015-6026
Published online Oct 21, 2020. doi: 10.3748/wjg.v26.i39.6015
Single access laparoscopic total colectomy for severe refractory ulcerative colitis
John Burke, Des Toomey, Frank Reilly, Ronan Cahill
John Burke, Des Toomey, Frank Reilly, Department of Colorectal Surgery, Beaumont Hospital, Dublin D09, Ireland
Ronan Cahill, Department of Surgery, Mater Misericordiae University Hospital, Dublin D07, Ireland
Author contributions: All authors contributed substantially to this work; Cahill R was involved in study concept and design; Burke J, Toomey D and Reilly F were involved in data collection; all authors contributed to data analysis, manuscript drafting and approval.
Institutional review board statement: The study was reviewed and approved by the Institutional Review Board at the Mater Misericordiae University Hospital Clinical Audit and Effectiveness Committee.
Conflict-of-interest statement: No author has a conflict of interest with regard to the subject of this work.
Data sharing statement: Data will be made available via the UCD data registry and also on request.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Ronan Cahill, FRCS, MBBAOBCh, MD, Professor, Department of Surgery, Mater Misericordiae University Hospital, 47 Eccles Street, Dublin D01, Ireland.
Received: December 31, 2019
Peer-review started: December 31, 2019
First decision: February 19, 2020
Revised: June 15, 2020
Accepted: October 12, 2020
Article in press: October 12, 2020
Published online: October 21, 2020
Research background

Single access laparoscopy (SAL) is a modification of standard laparoscopy that has not be studied in detail for the operation of total colectomy in patients sick with ulcerative colitis (UC). Here we examine its impact in this patient cohort.

Research motivation

Clinical outcomes were examined along with measure of operative efficiency to define the comparative advantages of the SAL approach for this surgery.

Research objectives

SAL was safely and efficiently applied meaning this approach can be considered in future for this patient group.

Research methods

Clinical data along with patient demographics and outcomes including complications.

Research results

SAL was associated with satisfactory outcomes in patients sick with UC and compared favourably to standard surgery in terms of cost and operative time.

Research conclusions

SAL was confirmed as a therapeutic option for surgical approach for patients with UC and should be considered more often where the skillsets and technology exist.

Research perspectives

Further work can expand on this series in particular to show the generalisability of these findings and also define better the relative merits of the different operative approaches now available.