Published online Sep 15, 2000. doi: 10.3748/wjg.v6.iSuppl3.31
Revised: June 24, 2000
Accepted: July 1, 2000
Published online: September 15, 2000
AIM: To evaluate the clinical significance of early nutrition support in severe head injured patients.
METHODS: One hundred and forty cases (GCS ≤ 8) were randomly divided into 5 groups: each one had 28 cases with similar data in age, sex, GCS or prognosis (P > 0.05, χ2 = 0.43). Group A were given early parenteral nutrition (PN) and enteral nutrition (EN); group B were given early PN and EN after 1 wk; group C were given PN only for more than 2 wk; group D were given early PN only and group E were given traditional delayed EN. The clinical nutritional data, the rate of complication and the progrosis were observed and statistical comparison (t test and Chi square test) was made.
RESULTS: The severe head-injured patients could get nourishment from different ways at early stage. Groups A and B had better outcomes and their clinical data such as blood glucose, blood total goblin, blood albumin, lymphocyte amount were superior to that of groups D and E (P < 0.05, t = 2.12) and were the same as that of group C (P > 0.05, t = 0.98), the rate of complication and the prognosis of patients were better than that of the other groups. Group C had similar nutritional data in early stage, but had higher rate of complication and infection after 2 wk than group A or B (P < 0.01, χ2 = 7.38). Group A had lower rate of gastric hemorrhage.
CONCLUSION: Early rational nutritional support had significant effect in the severe head-injured patients. The nutritional support of early PN and EN could afford nourishment, protect and improve the gastroenteric function, reduce the rate of complication. So it is a rational nutritional support.