Published online Oct 15, 1998. doi: 10.3748/wjg.v4.iSuppl2.98
Revised: August 2, 1998
Accepted: August 24, 1998
Published online: October 15, 1998
AIM: To a study the real state of health of HBV carriers (ASC for ahort) in the view of hemodynamics.
METHODS: The nailfold microcirculation of 60 patients with HBV (51 cases males, 9 females, the average age 29.5 ± 11.9 years) was studied by MCX-5A systemic micro-circulation instrument. And the hepatic hemodynamics and hemomicirculation state of 118 patients with HBV ( 90 males, 28 females, the average age 29.2 ± 11.4 years) were studied by RG-2B systemic rehohepatography. In 9 patients with HBV, we performed hepatic biopsies. All the results were compared with that in normals.
RESULTS: After a close clinical observation and pathological study of liver in 60 cases of what is called HBV carriers, we found that the single and general integral values of their nailfold microcirculation (0.38 ± 0.32, 0.89 ± 0.52, 0.97 ± 0.69, 2.24 ± 0.96) were significantly different from the values of healthy group (0.17 ± 0.09, 0.49 ± 0.27, 0.55 ± 0.31, 1.21 ± 0.47), (P < 0.01). And its abnormal rate (55.0%) was markedly higher than the abnormal rate of healthy group (3.3%) (P < 0.01). The values of hs, ha/hs, ta of the rehohepatography in 118 cases of the patients (0.0949 Ω± 0.0297 Ω, 0.226 ± 0.103, 0.223 s ± 0.045 s), were significantly different from the values of healthy group (0.1230 ± 0.0258 Ω ,0.165 ± 0.080, 0.175 s ± 0.022 s), (P < 0.01). And its abnormal rate (36.5%) was markedly higher than the abnormal rate of healthy group (0). (P < 0.01). After performing hepatic biopsy in 9 cases of the patients, we found chronic persistent hepatitis in 5 cases and chronic active hepatitis in 2 cases, and only 2 cases have no significant pathologic damage.
CONCLUSION: Most clinical HBV carriers have a mild to middle hepatic damage and they belong to sub-healthy state. Nearly none of them is healthy.