Abstracts
Copyright ©The Author(s) 1998. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Oct 15, 1998; 4(Suppl2): 67-67
Published online Oct 15, 1998. doi: 10.3748/wjg.v4.iSuppl2.67
Pathologic analysis of 4451 cases with digestive tract cancer
Tong Xu, Li-Ping Fang, Jing Li, Wen-Qing Liu, Zuo-Yu Zhou, Cui-Ping Qiu, Xin-Hua Yu, Tu-Peng Si, Li-Juan He, Xian-Lai Fang, Zhi-Hua Meng, Ying-Han Li, Li-Hua Jiang, De-Yuan Luo
Tong Xu, Li-Ping Fang, Jing Li, Wen-Qing Liu, Zuo-Yu Zhou, Pathological Department, Yue Bei People’s Hospital, Shaoguan 512026, Guangdong Province, China
Cui-Ping Qiu, Xin-Hua Yu, Neoplastic Department, Yue Bei People’s Hospital, Shaoguan 512026, Guangdong Province, China
Tu-Peng Si, Li-Juan He, Endoscopy Room, Yue Bei People’s Hospital, Shaoguan 512026, Guangdong Province, China
Xian-Lai Fang, Zhi-Hua Meng, Ying-Han Li, Department of Radiology, Yue Bei People’s Hospital, Shaoguan 512026, Guangdong Province, China
Li-Hua Jiang, De-Yuan Luo, Department of Surgery, Yue Bei People’s Hospital, Shaoguan 512026, Guangdong Province, China
Author contributions: All authors contributed equally to the work.
Correspondence to: Dr. Tong Xu, Pathological Department, Yue Bei People’s Hospital, Shaoguan 512026, Guangdong Province, China
Received: August 3, 1998
Revised: August 24, 1998
Accepted: September 10, 1998
Published online: October 15, 1998
Abstract

AIM: To analyse pathological characteristics of 4451 cases of digestive tract cancer, and study its clinical significance.

METHODS: All cases were unselected patients of digestive tract cancer who were diagnosed and operated in our hospital during the period 1983-19 97, and the diagnosis confirmed by pathological examination. Comparation was mad e between different age groups (young < 30, middle 30-40, old 40-70, very old > 70) on the tasis of location of the primary cancer.

RESULTS: All patients aged from 7-87 years, mean 61 years, the ratio of male to female is 2:1. The distribution of age is young (3.5%), middle (9.5%), old (70%), very old group (17%). Distribution of cancer is esophagus 17.1%, cardiac and gastric cancer, 50.7%, and carcinoma of large intestine, 31.6%. In the old and very old age groups well-differentiated and poorly differentiated squamous cell carcinoma of the esophagus, well-differentiated and po orly differentiated adenocarcinoma, myxoadenocarcinoma, papillary adenocarcinoma were significantly higher than those of young and middle age groups (P < 0.01, P < 0.05, P < 0.05). Cardiac and gastric cancer have similar pathological presentations with adenocarcinoma predominates and adenosquamous carcinoma and squamous carcinoma occur infrequently. The incidence of poorly differentiated adenocarcinoma (79% of all cancer of the same location) and ring cell carcinoma (90% of all cancers of the same pathological type) is high in card ia and stomach among all cases. The metastatic rate of cardiac and gastric cancer is 11%; The recurrence rate of residual gastric cancer is 8% with high malign ancy and poor prognosis. Precancerous lesions existed in 687 cases; The ratio to all cases is 1:6.5. There are 193 cases of early cancer (4.3% of all cases ).

CONCLUSION: It is valueable to perform screening test to exam routinely (such as barium-air double contrast radiography, rectal touch, endoscopy + biopsy), as well as to get a timely pathological diagnosis for the detection and management of gastrointestinal tract carcinoma and early cancer, especially for young and middle age groups.

Keywords: Digestive system neoplasms/pathology, Carcino ma, squamous cell/pathology, Adenocarcinoma/pathology, Precancerous conditions/pathology