Letter to the Editor
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. May 21, 2025; 31(19): 103727
Published online May 21, 2025. doi: 10.3748/wjg.v31.i19.103727
Limitations and suggestions for emphysematous pancreatitis: Diagnosis, treatment, and prognosis
Xiang Li, Hong-Juan Li, Wei-Yao-Zhen He, Hai-Yan Fu
Xiang Li, Department of Radiology, The Third People’s Hospital of Kunming, Yunnan Clinical Medicine Center for Infectious Diseases, Kunming 650200, Yunnan Province, China
Hong-Juan Li, Hai-Yan Fu, Hospice Care Center, The Third People’s Hospital of Kunming, Yunnan Clinical Medicine Center for Infectious Diseases, Kunming 650200, Yunnan Province, China
Wei-Yao-Zhen He, Department of Ultrasound Intervention, The Third People’s Hospital of Kunming, Yunnan Clinical Medicine Center for Infectious Diseases, Kunming 650200, Yunnan Province, China
Author contributions: Fu HY conceptualized this study and drafted manuscript; Li X and Li HJ participated in the discussion; Li X and He WYZ revised the manuscript; and all authors had read and agreed to the final version of the manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hai-Yan Fu, MD, Postdoctoral Fellow, Associate Chief Physician, Hospice Care Center, The Third People’s Hospital of Kunming, No. 319 Wujing Road, Guandu District, Kunming 650200, Yunnan Province, China. fuhaiyan0622@163.com
Received: November 28, 2024
Revised: March 16, 2025
Accepted: April 1, 2025
Published online: May 21, 2025
Processing time: 173 Days and 23.2 Hours
Abstract

We read with great interest the article by Cao et al on 15 cases of emphysematous pancreatitis (EP). The study highlights the high mortality rate associated with EP and emphasizes the role of next-generation sequencing (NGS) in identifying its etiology. Additionally, it suggests treatment strategies such as antimicrobial therapy and early percutaneous catheter drainage, which may improve patient outcomes. However, we have identified certain limitations related to case selection, the evaluation of NGS technology, and the timing of computed tomography scans. To enhance the study’s findings, we recommend expanding the study population, systematically evaluating the role of NGS in EP, and providing a more detailed analysis of the antibiotic initiation and duration. Furthermore, specifying the timing of computed tomography scans would improve clarity. Addressing these concerns could strengthen the study’s contribution to the evidence-based management of EP, offering valuable insights for clinical practice.

Keywords: Emphysematous pancreatitis; Next-generation sequencing; Computed tomography; Diagnosis; Treatment

Core Tip: The results section of the abstract states that 5 cases of extensive emphysematous pancreatitis accounted for 33.3%, not 66.7%, and 7 cases of early-onset emphysematous pancreatitis accounted for 46.7%, not 47.1%. We recommend including details on the timing of antibiotic initiation and duration, as well as the timing of EP detection by computed tomography.