Kamimura K, Terai S. Importance of understanding a diagnostic-treatment algorithm for primary hyperparathyroidism-induced acute pancreatitis during pregnancy. World J Gastroenterol 2025; 31(18): 105866 [DOI: 10.3748/wjg.v31.i18.105866]
Corresponding Author of This Article
Kenya Kamimura, MD, PhD, Professor, Department of General Medicine, Niigata University, 1-757 Asahimachi do-ri, Niigata 9518510, Japan. kenya-k@med.niigata-u.ac.jp
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Letter to the Editor
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. May 14, 2025; 31(18): 105866 Published online May 14, 2025. doi: 10.3748/wjg.v31.i18.105866
Importance of understanding a diagnostic-treatment algorithm for primary hyperparathyroidism-induced acute pancreatitis during pregnancy
Kenya Kamimura, Shuji Terai
Kenya Kamimura, Department of General Medicine, Niigata University, Niigata 9518510, Japan
Kenya Kamimura, Shuji Terai, Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 9518510, Japan
Author contributions: Kamimura K and Terai S contributed to the data analyses, manuscript drafting, and writing.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Kenya Kamimura, MD, PhD, Professor, Department of General Medicine, Niigata University, 1-757 Asahimachi do-ri, Niigata 9518510, Japan. kenya-k@med.niigata-u.ac.jp
Received: February 10, 2025 Revised: March 12, 2025 Accepted: March 26, 2025 Published online: May 14, 2025 Processing time: 94 Days and 1.3 Hours
Abstract
In this article, we have commented on the article by Augustin et al. The authors presented a systematic review of the diagnosis, treatment, and outcomes of primary hyperparathyroidism-induced acute pancreatitis in pregnant women. Since acute pancreatitis during pregnancy could cause maternal as well as fetal adverse outcomes, understanding this pathology is essential. Although there are various etiologies of acute pancreatitis during pregnancy, primary hyperparathyroidism is one of the causes that complicate hypercalcemia. Along with conventional treatment for acute pancreatitis, parathyroidectomy can effectively normalize calcium levels and improve acute pancreatitis. Augustin et al have provided vital information that can enable physicians to understand and treat hyperparathyroidism-induced acute pancreatitis in pregnant women, which could contribute to better maternal and fetal outcomes. In addition, since primary hyperparathyroidism is associated with multiple endocrine neoplasia, further consideration regarding screening for multiple endocrine neoplasia might lead to better prognoses.
Core Tip: Primary hyperparathyroidism-induced acute pancreatitis during pregnancy is a rare condition and can cause maternal and fetal adverse outcomes. Therefore, early diagnosis and appropriate therapeutic intervention are essential. This article comments on the recent systematic review of this condition published in the World Journal of Gastroenterology. In addition, multiple endocrine neoplasia screening is recommended for the better prognosis of the cases.
