Published online Sep 14, 2021. doi: 10.3748/wjg.v27.i34.5715
Peer-review started: March 1, 2021
First decision: April 18, 2021
Revised: April 28, 2021
Accepted: August 2, 2021
Article in press: August 2, 2021
Published online: September 14, 2021
Recently, increasing attention has been paid to the application of artificial intelligence (AI) to the diagnosis of diverse hepatic diseases, which comprises traditional machine learning and deep learning. Recent studies have shown the possible value of AI based data mining in predicting the incidence of hepatitis, classifying the different stages of hepatitis, diagnosing or screening for hepatitis, forecasting the progression of hepatitis, and predicting response to antiviral drugs in chronic hepatitis C patients. More importantly, AI based on radiology has been proven to be useful in predicting hepatitis and liver fibrosis as well as grading hepatocellular carcinoma (HCC) and differentiating it from benign liver tumors. It can predict the risk of vascular invasion of HCC, the risk of hepatic encephalopathy secondary to hepatitis B related cirrhosis, and the risk of liver failure after hepatectomy in HCC patients. In this review, we summarize the application of AI in hepatitis, and identify the challenges and future perspectives.
Core Tip: Currently, there is a need of a comprehensive review to introduce the applications of artificial intelligence (AI) in hepatitis. We first discuss the possible value of AI based data mining in predicting the incidence of hepatitis, classifying the different stages of hepatitis, diagnosing or screening for hepatitis, forecasting the progression of hepatitis, and predicting response to antiviral drugs in chronic hepatitis C patients. In addition, we introduce the applications of AI based on radiology in predicting hepatitis and liver fibrosis, grading hepatocellular carcinoma (HCC) and differentiating it from benign liver tumors, and predicting the risk of vascular invasion of HCC as well as the risk of hepatic encephalopathy secondary to hepatitis B related cirrhosis.