Okasha HH, Awad A, El-meligui A, Ezzat R, Aboubakr A, AbouElenin S, El-Husseiny R, Alzamzamy A. Cystic pancreatic lesions, the endless dilemma. World J Gastroenterol 2021; 27(21): 2664-2680 [PMID: 34135548 DOI: 10.3748/wjg.v27.i21.2664]
Corresponding Author of This Article
Hussein Hassan Okasha, MD, Professor, Department of Internal Medicine and Gastroenterology, Hepatology Unit, Kasr Al-Aini Hospitals, Cairo University, Kasr Al-Aini Street, Cairo 11562, Egypt. okasha.hussein@gmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Frontier
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Jun 7, 2021; 27(21): 2664-2680 Published online Jun 7, 2021. doi: 10.3748/wjg.v27.i21.2664
Cystic pancreatic lesions, the endless dilemma
Hussein Hassan Okasha, Abeer Awad, Ahmed El-meligui, Reem Ezzat, Ashraf Aboubakr, Sameh AbouElenin, Ramy El-Husseiny, Ahmed Alzamzamy
Hussein Hassan Okasha, Abeer Awad, Ahmed El-meligui, Department of Internal Medicine and Gastroenterology, Hepatology Unit, Kasr Al-Aini Hospitals, Cairo University, Cairo 11562, Egypt
Reem Ezzat, Department of Internal Medicine and Gastroenterology, Hepatology Unit, Assuit University, Assuit 71515, Egypt
Ashraf Aboubakr, Ahmed Alzamzamy, Department of Gastroenterology and Hepatology, Maadi Armed Forces Medical Complex, Military Medical Academy, Cairo 11441, Egypt
Sameh AbouElenin, Department of Gastroenterology and Hepatology, Military Medical Academy, Cairo 11441, Egypt
Ramy El-Husseiny, Department of Hepatology and Tropical Medicine, National Hepatology and Tropical Medicine Research Institute (NHTMRI), Cairo 11441, Egypt
Author contributions: Awad A, El-meligui A and Ezzat R have been involved equally in writing the manuscript; Aboubakr A, AbouElenin S, El-Husseiny R and Alzamzamy A have been involved equally in read and revise the manuscript; Okasha HH revised and approved the final manuscript; all authors have read and approved the final manuscript.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hussein Hassan Okasha, MD, Professor, Department of Internal Medicine and Gastroenterology, Hepatology Unit, Kasr Al-Aini Hospitals, Cairo University, Kasr Al-Aini Street, Cairo 11562, Egypt. okasha.hussein@gmail.com
Received: March 17, 2021 Peer-review started: March 17, 2021 First decision: April 5, 2021 Revised: April 14, 2021 Accepted: May 10, 2021 Article in press: May 10, 2021 Published online: June 7, 2021
Abstract
Cystic pancreatic lesions involve a wide variety of pathological entities that include neoplastic and non-neoplastic lesions. The proper diagnosis, differentiation, and staging of these cystic lesions are considered a crucial issue in planning further management. There are great challenges for their diagnostic models. In our time, new emerging methods for this diagnosis have been discovered. Endoscopic ultrasonography-guided fine-needle aspiration cytology with chemical and molecular analysis of cyst fluid and EUS-guided fine needle-based confocal laser endomicroscopy, through the needle microforceps biopsy, and single-operator cholangioscopy/pancreatoscopy are promising methods that have been used in the diagnosis of cystic pancreatic lesions. Hereby we discuss the diagnosis of cystic pancreatic lesions and the benefits of various diagnostic models.
Core Tip: Pancreatic cystic lesions are commonly recognized with increasing frequency and have become a more common finding in clinical practice. Today, there has been an increased incidence in cystic pancreatic lesions that have in turn caused a lot of diagnostic modalities to emerge. We discuss the various methods of the diagnosis of cystic pancreatic lesions and compare these modalities.
