Published online Nov 21, 2016. doi: 10.3748/wjg.v22.i43.9650
Peer-review started: June 24, 2016
First decision: August 8, 2016
Revised: August 17, 2016
Accepted: August 30, 2016
Article in press: August 30, 2016
Published online: November 21, 2016
Choroidal and skin metastasis of colon cancer is rare. In women, the frequency of cutaneous metastasis from colon cancer as the primary lesion in is 9% and skin metastasis occurs in 0.81% of all colorectal cancers. We report a patient with colonic adenocarcinoma who presented with visual disorder in her right eye and scalp pain as her initial symptoms. Contrast-enhance orbital magnetic resonance imaging with fat suppression revealed an infrabulbar mass, and skin biopsy of the posterior parietal scalp confirmed adenocarcinoma. These symptoms were diagnosed as being caused by choroidal and skin metastases of colonic adenocarcinoma. We started palliative chemotherapy with oral capecitabine (1000 mg/m2, twice a day, on days 1-14) every 3 wk, which was effective at shrinking the brain masses and improving the visual disorder. This is the first report that capecitabine is effective at reducing a choroidal and cutaneous metastatic lesion from right-sided colorectal cancer.
Core tip: This case report describes a rare choroidal and skin metastasis of colon cancer and demonstrates that capecitabine is effective at reducing a choroidal and skin metastatic lesion from right-sided colorectal cancer.