Retrospective Study
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Nov 14, 2016; 22(42): 9394-9399
Published online Nov 14, 2016. doi: 10.3748/wjg.v22.i42.9394
Irritable bowel syndrome evaluation using computed tomography colonography
Hideki Ohgo, Hiroyuki Imaeda, Minoru Yamaoka, Kazuaki Yoneno, Naoki Hosoe, Takeshi Mizukami, Hidetomo Nakamoto
Hideki Ohgo, Hiroyuki Imaeda, Department of Gastroenterology, Saitama Medical University, Saitama 350-0495, Japan
Hideki Ohgo, Hiroyuki Imaeda, Minoru Yamaoka, Kazuaki Yoneno, Hidetomo Nakamoto, Department of General Internal Medicine, Saitama Medical University, Saitama 350-0495, Japan
Naoki Hosoe, Center for Diagnostic and Therapeutic Endoscopy, School of Medicine, Keio University, Tokyo 160-8582, Japan
Takeshi Mizukami, Endoscopy Center, NHO Kurihama Medical and Addiction Center, Kanagawa 239-0841, Japan
Author contributions: Ohgo H and Imaeda H planner of study design, enrollment of patients; Yamaoka M and Yoneno K enrollment of patients; Hosoe N advisor of study design, data analyst; Mizukami T advisor of study design; Mizukami T and Nakamoto H supervisor.
Institutional review board statement: The study protocol was approved by the institutional review board at our institutions.
Informed consent statement: Written informed consent was obtained from all the patients.
Conflict-of-interest statement: The authors disclosed no financial relationships relevant to this study.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Hiroyuki Imaeda, MD, Department of Gastroenterology, Saitama Medical University, 38 Morohongo, Moroyama-machi, Iruma-gun, Saitama 350-0495, Japan. imaedahi@yahoo.co.jp
Telephone: +81-49-2761667 Fax: +81-49-2761667
Received: June 29, 2016
Peer-review started: June 30, 2016
First decision: July 29, 2016
Revised: August 24, 2016
Accepted: September 12, 2016
Article in press: September 12, 2016
Published online: November 14, 2016
Abstract
AIM

To evaluate the morphology of the colon in patients with irritable bowel syndrome (IBS) by using computed tomography colonography (CTC).

METHODS

Twelve patients with diarrhea type IBS (IBS-D), 13 patients with constipation type IBS (IBS-C), 12 patients with functional constipation (FC) and 14 control patients underwent colonoscopy following CTC. The lengths of the rectosigmoid colon, transverse colon and the total colon were measured. The diameters of the rectum, sigmoid colon, descending colon, transverse colon, and ascending colon were measured.

RESULTS

The mean length of the total colon was 156.5 cm in group C, 158.9 cm in group IBS-D, 172.0 cm in group IBS-C, and 188.8 cm in group FC. The total colon in group FC was significantly longer than that in group C (P < 0.05). The mean length of the rectosigmoid colon was 56.2 cm, 55.9 cm, 63.6cm, and 77.4 cm (NS). The mean length of the transverse colon was 49.9 cm, 43.1 cm, 57.0 cm, and 55.0 cm. The transverse colon in group IBS-D was significantly shorter than that in group IBS-C (P < 0.01) and that in group FC (P = 0.02). The mean diameter of the sigmoid colon was 4.0 cm, 3.3 cm, 4.2 cm, and 4.3 cm (NS). The mean diameter of the descending colon was 3.6 cm, 3.1 cm, 3.8 cm, and 4.3 cm. The descending colon diameter in group IBS-D was significantly less than that in group IBS-C (P = 0.03) and that in group FC (P < 0.001). The descending colon diameter in group FC was significantly greater than that in group C (P = 0.04). The mean diameter of the transverse colon was 4.4 cm, 3.3 cm, 4.2 cm, and 5.0 cm (NS).

CONCLUSION

CT colonography might contribute the clarification of subtypes of IBS.

Keywords: Constipation, Irritable bowel syndrome, Computed tomography colonography

Core tip: We report the morphology difference between diarrhea type IBS (IBS-D) and constipation type IBS (IBS-C). 12 patients with IBS-D, 13 patients with IBS-C, 12 patients with functional constipation (FC) and 14 control patients underwent colonoscopy following computed tomography colonography (CTC). The lengths and the diameters of the colon were measured. The rectosigmoid colon and transverse colon in IBS-D are shorter than that in IBS-C and FC. The sigmoid colon and descending colon in IBS-D has a diameter smaller than that in IBS-C and FC. The colonic morphology in IBS-D might be different from that in IBS-C and FC. CTC might contribute the clarification of IBS.