Clinical Trials Study
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World J Gastroenterol. Jul 21, 2014; 20(27): 9162-9169
Published online Jul 21, 2014. doi: 10.3748/wjg.v20.i27.9162
Biofeedback-guided pelvic floor exercise therapy for obstructive defecation: An effective alternative
Ma-Mu-Ti-Jiang A ba-bai-ke-re, Ni-Re Wen, Yun-Long Hu, Liang Zhao, Tuerhongjiang Tuxun, Aierhati Husaiyin, Yalikun Sailai, Alimujiang Abulimiti, Yun-Hai Wang, Peng Yang
Ma-Mu-Ti-Jiang A ba-bai-ke-re, Tuerhongjiang Tuxun, Aierhati Husaiyin, Yalikun Sailai, Alimujiang Abulimiti, Liang Zhao, General Surgical Department of First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, Xinjiang Uygur Autonomous Region, China
Ni-Re Wen, Otolaryngological Department of Urumqi Military Hospital of Lanzhou Military Center, Urumqi 830011, Xinjiang Uygur Autonomous Region, China
Yun-Long Hu, Peng Yang, Surgical Department, First Affiliated Hospital, Xinjiang Medical University, Urumqi 830011, Xinjiang Uygur Autonomous Region, China
Yun-Hai Wang, Digestive and Vascular Surgical Center of First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, Xinjiang Uygur Autonomous Region, China
Author contributions: A ba-bai-ke-re MMTJ contributed to the conception, design, and revision of this article for critically important intellectual content; Tuxun T, Husaiyin A and Abulimiti A performed control, recording, and data acquisition; Hu YL and Abulimiti A provided substantial contributions, including statistical calculations and study design; Wen NR and Zhao L performed intervention control, recording, data acquisition, and final approval of the version to be published; Sailai Y, Wang YH, and Yang P performed analysis and interpretation of the data.
Supported by Research Award Fund of First Affiliated Hospital of Xinjiang Medical University, Fund Serial No. 2012YFY30
Correspondence to: Yalikun Sailai, Surgical Assistant Professor, MD, General Surgical Department of First Affiliated Hospital of Xinjiang Medical University, Liyushan Road, No 1, Urumqi 830011, Xinjiang Uygur Autonomous Region, China. 834140633@qq.com
Telephone: +86-991-4366142 Fax: +86-991-4366142
Received: December 30, 2013
Revised: February 26, 2014
Accepted: April 15, 2014
Published online: July 21, 2014
Abstract

AIM: To compare biofeedback-guided pelvic floor exercise therapy (BFT) with the use of oral polyethylene glycol (PEG) for the treatment of obstructive defecation.

METHODS: A total of 88 subjects were assigned to treatment with either BFT (n = 44) or oral PEG (n = 44). Constipation symptoms (including difficult evacuation, hard stool, digitation necessity, incomplete emptying sensation, laxative dependence, perianal pain at defecation, and constipation satisfaction), Wexner Scores, and quality of life scores were assessed after 1, 3, and 6 mo.

RESULTS: At the 6 mo follow-up, the symptoms of the BFT group patients showed significantly greater improvements compared with the PEG group regarding difficult evacuation, hard stools, digitation necessity, laxative dependence, perianal pain at defecation, constipation satisfaction, Wexner Constipation Score, and quality of life score (P < 0.05). The quality of life score of the BFT group at the final follow-up time (6 mo) was 80 ± 2.2. After a complete course of training, improvements in the clinical symptoms of the BFT group were markedly improved (P < 0.05), and the Wexner Constipation Scores were greatly decreased compared with the oral PEG group (P < 0.05).

CONCLUSION: We concluded that manometric biofeedback-guided pelvic floor exercise training is superior to oral polyethylene glycol therapy for obstructive defecation.

Keywords: Obstructive defecation, Biofeedback, Polyethylene glycol

Core tip: Until now, there have been no standard treatment methods for obstructed defecation. Although we believe biofeedback is more beneficial for obstructive defecation, recent controlled studies indicate that the efficacy of manometric biofeedback treatment for obstructive defecation remains controversial. The main purpose of this research was to assess and compare the quality of life scores of patients diagnosed with obstructive defecation following treatment with biofeedback therapy or oral polyethylene glycol management. Biofeedback had the clear effect of teaching patients how to squeeze and relax their anorectal and pelvic floor muscles during defecation. The data in this study show a clear superiority of biofeedback related to oral polyethylene glycol for the treatment of this subtype of constipation. If this research was extended to large multicenter randomized trials and its efficiency proven, biofeedback could become the standard treatment method for obstructive defecation.