Published online Mar 25, 1996. doi: 10.3748/wjg.v2.i1.22
Revised: November 19, 1995
Accepted: December 21, 1995
Published online: March 25, 1996
AIM: To establish the prevalence of bacterial infection in cirrhotic patients with hepatocellular carcinoma (HCC).
METHODS: All 719 cirrhotic patients with HCC were investigated retrospectively for occurrence of bacterial infections.
RESULTS: The incidence of bacterial infection was 15.4% (111/719). According to Child-Pugh classification, the incidences of bacterial infection in Class A, B and C were 2.3%, 8.0%, and 26.4%, respectively. The bacterial infection incidence increased with the severity of cirrhosis, and severe bacterial infections usually occurred in Child-Pugh class B and C patients.
CONCLUSION: The susceptibility of HCC patients to bacterial infection is mainly due to the underlying cirrhosis and not to the HCC itself.