Clinical Articles
Copyright ©The Author(s) 1996. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 25, 1996; 2(1): 22-24
Published online Mar 25, 1996. doi: 10.3748/wjg.v2.i1.22
Bacterial infections in cirrhotic patients with hepatocellular carcinoma
Xiao-Wei Xiao, Ya-Jie Zhou, Feng-Yun Guo
Xiao-Wei Xiao, Ya-Jie Zhou, Feng-Yun Guo, Physician, The Central Hospital of Jianghan Oil Field, Jianghan 433124, Hubei Province China
Author contributions: All authors contributed equally to the work.
Correspondence to: Dr. Xiao-Wei Xiao, The Central Hospital of Jianghan Oil Field, Jianghan 433124, Hubei Province, China.
Telephone: +86-726-2514192
Received: September 20, 1995
Revised: November 19, 1995
Accepted: December 21, 1995
Published online: March 25, 1996
Abstract

AIM: To establish the prevalence of bacterial infection in cirrhotic patients with hepatocellular carcinoma (HCC).

METHODS: All 719 cirrhotic patients with HCC were investigated retrospectively for occurrence of bacterial infections.

RESULTS: The incidence of bacterial infection was 15.4% (111/719). According to Child-Pugh classification, the incidences of bacterial infection in Class A, B and C were 2.3%, 8.0%, and 26.4%, respectively. The bacterial infection incidence increased with the severity of cirrhosis, and severe bacterial infections usually occurred in Child-Pugh class B and C patients.

CONCLUSION: The susceptibility of HCC patients to bacterial infection is mainly due to the underlying cirrhosis and not to the HCC itself.

Keywords: Liver cirrhosis, Liver neoplasms, Bacterial infection, Hepatocellular carcinoma (HCC)