Published online Mar 25, 1996. doi: 10.3748/wjg.v2.i1.20
Revised: November 14, 1995
Accepted: December 11, 1995
Published online: March 25, 1996
AIM: To investigate the alterations of red blood cell (RBC) immunoadherence function in patients with hepatitis B.
METHODS: RBCC3bRR, RBCICRR and serum CIC levels were measured in 42 patients with acute and chronic hepatitis B at active and convalescence stages.
RESULTS: RBCC3bRRs at the active/acute stage of hepatitis were decreased, with 13.54% ± 5.23% in acute hepatitis, 7.61% ± 4.12% in acute fulminant hepatitis, and 16.18% ± 6.10% in chronic hepatitis, all of which were lower than the value in normal persons (18.12% ± 3.91%). At the quiescent/recovery stage of hepatitis, the RBCC3bRRs were increased significantly. The changes of RBCICRR and serum CIC level were contrary to those of RBCC3bRR.
CONCLUSION: RBC immunoadherence function is decreased in acute and chronic hepatitis, and the decrease is in direct proportion to severity of the diseases.