Brief Article
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World J Gastroenterol. Aug 14, 2013; 19(30): 4966-4972
Published online Aug 14, 2013. doi: 10.3748/wjg.v19.i30.4966
Residual common bile duct stones on direct peroral cholangioscopy using ultraslim endoscope
Shu-Wei Huang, Cheng-Hui Lin, Mu-Shien Lee, Yung-Kuan Tsou, Kai-Feng Sung
Shu-Wei Huang, Cheng-Hui Lin, Mu-Shien Lee, Yung-Kuan Tsou, Kai-Feng Sung, Department of Gastroenterology and Hepatology, Division of Digestive Therapeutic Endoscopy, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan 333, Taiwan
Author contributions: Huang SW wrote the manuscript; Tsou YK conceptualized and designed the study, performed direct peroral cholangioscopy and analyzed and interpreted the data; Lee MS and Sung KF collected data; Lin CH performed direct peroral cholangioscopy, revised the manuscript and gave final approval of the version to be published.
Supported by Chang Gung Memorial Hospital, No. CMRPG300011
Correspondence to: Yung-Kuan Tsou, MD, Department of Gastroenterology and Hepatology, Division of Digestive Therapeutic Endoscopy, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 5, Fu-Shin Street, Kweishan, Taoyuan 333, Taiwan. flying3454@xuite.net
Telephone: +886-3-3281200-8108 Fax: +886-3-3272236
Received: March 13, 2013
Revised: May 16, 2013
Accepted: June 19, 2013
Published online: August 14, 2013
Abstract

AIM: To detect and manage residual common bile duct (CBD) stones using ultraslim endoscopic peroral cholangioscopy (POC) after a negative balloon-occluded cholangiography.

METHODS: From March 2011 to December 2011, a cohort of 22 patients with CBD stones who underwent both endoscopic retrograde cholangiography (ERC) and direct POC were prospectively enrolled in this study. Those patients who were younger than 20 years of age, pregnant, critically ill, or unable to provide informed consent for direct POC, as well as those with concomitant gallbladder stones or CBD with diameters less than 10 mm were excluded. Direct POC using an ultraslim endoscope with an overtube balloon-assisted technique was carried out immediately after a negative balloon-occluded cholangiography was obtained.

RESULTS: The ultraslim endoscope was able to be advanced to the hepatic hilum or the intrahepatic bile duct (IHD) in 8 patients (36.4%), to the extrahepatic bile duct where the hilum could be visualized in 10 patients (45.5%), and to the distal CBD where the hilum could not be visualized in 4 patients (18.2%). The procedure time of the diagnostic POC was 8.2 ± 2.9 min (range, 5-18 min). Residual CBD stones were found in 5 (22.7%) of the patients. There was one residual stone each in 3 of the patients, three in 1 patient, and more than five in 1 patient. The diameter of the residual stones ranged from 2-5 mm. In 2 of the patients, the residual stones were successfully extracted using either a retrieval balloon catheter (n = 1) or a basket catheter (n = 1) under direct endoscopic control. In the remaining 3 patients, the residual stones were removed using an irrigation and suction method under direct endoscopic visualization. There were no serious procedure-related complications, such as bleeding, pancreatitis, biliary tract infection, or perforation, in this study.

CONCLUSION: Direct POC using an ultraslim endoscope appears to be a useful tool for both detecting and treating residual CBD stones after conventional ERC.

Keywords: Balloon-occluded cholangiography, Common bile duct stones, Endoscopic retrograde cholangiography, Peroral cholangioscopy, Residual stones

Core tip: Balloon-occluded cholangiography is generally performed to confirm bile duct clearance after performing endoscopic retrograde cholangiography (ERC) for stone retrieval. However, balloon-occluded cholangiography may be an imperfect tool for this diagnostic purpose. In this case series, we demonstrated that 22.7% of patients still had residual stones detected on peroral cholangioscopy after a negative balloon-occluded cholangiography was obtained. All of the residual stones were retracted on the cholangioscopy. Our results reveal that peroral cholangioscopy appears to be a useful tool for both detecting and treating residual common bile duct stones after conventional ERC.