Case Report
Copyright ©2012 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. Nov 28, 2012; 18(44): 6515-6520
Published online Nov 28, 2012. doi: 10.3748/wjg.v18.i44.6515
Giant solitary fibrous tumor arising from greater omentum
Liang Zong, Ping Chen, Guang-Yao Wang, Qun-Shan Zhu
Liang Zong, Ping Chen, Guang-Yao Wang, Qun-Shan Zhu, Department of Gastrointestinal Surgery, Subei People’s Hospital, Yangzhou University, Yangzhou 225001, Jiangsu Province, China
Author contributions: Zong L and Chen P performed the majority of study and prepared the manuscript; Wang GY and Zhu QS collected the clinical data.
Correspondence to: Ping Chen, Professor, Department of Gastrointestinal Surgery, Subei People’s Hospital, Yangzhou University, Yangzhou 225001, Jiangsu Province, China. chen86ky@126.com
Telephone: +86-514-87373285 Fax: +86-514-87937406
Received: July 15, 2012
Revised: September 25, 2012
Accepted: September 29, 2012
Published online: November 28, 2012
Abstract

Extrathoracic solitary fibrous tumors (SFTs) have been described at almost every anatomic location of human body, but reports of SFT in the abdominal cavity are rare. We herein present a rare case of SFT originating from greater omentum. Computed tomography revealed a 15.8 cm × 21.0 cm solid mass located at superior aspect of stomach. Open laparotomy confirmed its mesenchymal origin. Microscopically, its tissue was composed of non-organized and spindle-shaped cells exhibiting atypical nuclei, which were divided up by branching vessel and collagen bundles. Immunohistochemical staining showed that this tumor was negative for CD117, CD99, CD68, cytokeratin, calretinin, desmin, epithelial membrane antigen, F8 and S-100, but positive for CD34, bcl-2, α-smooth muscle actin and vimentin. The patient presented no evidence of recurrence during follow-up. SFT arising from abdominal cavity can be diagnosed by histological findings and immunohistochemical markers, especially for CD34 and bcl-2 positive cases.

Keywords: Greater omentum; Solitary fibrous tumor; Immunohistochemical markers