Guslandi M. Non-steroidal anti-inflammatory drugs-induced small intestinal injury and probiotic agents. World J Gastroenterol 2012; 18(31): 4241-4242 [PMID: 22919262 DOI: 10.3748/wjg.v18.i31.4241]
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Mario Guslandi, Professor, Gastroenterology Unit, S. Raffaele Hospital, Via Olgettina 60, 20132 Milano, Italy. email@example.com
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Letters To The Editor
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Non-steroidal anti-inflammatory drugs-induced small intestinal injury and probiotic agents
Mario Guslandi, Gastroenterology Unit, S. Raffaele University Hospital, 20132 Milan, Italy
Author contributions: Guslandi M contributed solely to this work.
Correspondence to: Mario Guslandi, Professor, Gastroenterology Unit, S. Raffaele Hospital, Via Olgettina 60, 20132 Milano, Italy. firstname.lastname@example.org
Telephone: +39-2-26431 Fax: +39-2-26433491
Received: December 2, 2011 Revised: March 8, 2012 Accepted: April 21, 2012 Published online: August 21, 2012
Intestinal bacteria play a role in the development of non-steroidal anti-inflammatory drugs (NSAID)-induced small intestinal injury. Agents such as probiotics, able to modify the gut ecology, might theoretically be useful in preventing small intestinal damage induced by NSAIDs. The clinical studies available so far do suggest that some probiotic agents can be effective in this respect.