Brief Article
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World J Gastroenterol. Jul 7, 2012; 18(25): 3260-3266
Published online Jul 7, 2012. doi: 10.3748/wjg.v18.i25.3260
Incidence and clinical features of endoscopic ulcers developing after gastrectomy
Woo Chul Chung, Eun Jung Jeon, Kang-Moon Lee, Chang Nyol Paik, Sung Hoon Jung, Jung Hwan Oh, Ji Hyun Kim, Kyong-Hwa Jun, Hyung Min Chin
Woo Chul Chung, Eun Jung Jeon, Kang-Moon Lee, Chang Nyol Paik, Sung Hoon Jung, Jung Hwan Oh, Department of Internal Medicine, The Catholic University of Korea, Seoul 130-709, South Korea
Ji Hyun Kim, Kyong-Hwa Jun, Hyung Min Chin, Department of Surgery, The Catholic University of Korea College of Medicine, Seoul 130-709, South Korea
Author contributions: Chung WC and Jeon EJ collected the data and designed the research; Lee KM, Paik CN, Jung SH, Oh JH, Kim JH, Jun KH and Chin HM contributed to the paper’s conception and carried out the literature research; Chung WC and Jeon EJ analyzed the data and wrote the paper.
Correspondence to: Eun Jung Jeon, MD, Department of Internal Medicine, The Catholic University of Korea, St. Paul’s Hospital, 620-56, Jeonnong 2-dong, Dongdaemun-gu, Seoul 130-709, South Korea. jwchulkr@catholic.ac.kr
Telephone: +82-2-9582487 Fax: +82-2-9687250
Received: August 23, 2011
Revised: April 4, 2012
Accepted: April 10, 2012
Published online: July 7, 2012
Abstract

AIM: To determine the precise incidence and clinical features of endoscopic ulcers following gastrectomy.

METHODS: A consecutive series of patients who underwent endoscopic examination following gastrectomy between 2005 and 2010 was retrospectively analyzed. A total of 78 patients with endoscopic ulcers and 759 without ulcers following gastrectomy were enrolled. We analyzed differences in patient age, sex, size of the lesions, method of operation, indications for gastric resection, and infection rates of Helicobacter pylori (H. pylori) between the nonulcer and ulcer groups.

RESULTS: The incidence of endoscopic ulcers after gastrectomy was 9.3% and that of marginal ulcers was 8.6%. Ulcers were more common in patients with Billroth II anastomosis and pre-existing conditions for peptic ulcer disease (PUD). Infection rates of H. pyloridid not differ significantly between the two groups. The patients who underwent operations to treat PUD had lower initial levels of hemoglobin and higher rates of hospital admission.

CONCLUSION: H. pylori was not an important factor in ulcerogenesis following gastrectomy. For patients who underwent surgery for PUD, clinical course of marginal ulcers was more severe.

Keywords: Gastrectomy, Marginal ulcer, Helicobacter pylori