Copyright
©2012 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. Mar 21, 2012; 18(11): 1176-1184
Published online Mar 21, 2012. doi: 10.3748/wjg.v18.i11.1176
Published online Mar 21, 2012. doi: 10.3748/wjg.v18.i11.1176
Management of portal hypertension in children
Roberto Gugig, Philip Rosenthal, Pediatric Gastroenterology, Hepatology and Nutrition, Deprtment of Pediatrics, University of California, San Francisco, CA 93638, United States
Author contributions: Gugig R and Rosenthal P contributed equally to this work.
Correspondence to: Philip Rosenthal, MD, Professor, Hepatology and Nutrition, Deprtment of Pediatrics, University of California, San Francisco, CA 93638, United States. prosenth@peds.ucsf.edu
Telephone: +1-415-4765892 Fax: +1-415-4761343
Received: June 5, 2011
Revised: November 2, 2011
Accepted: December 15, 2011
Published online: March 21, 2012
Revised: November 2, 2011
Accepted: December 15, 2011
Published online: March 21, 2012
Abstract
Portal hypertension can be caused by a wide variety of conditions. It frequently presents with bleeding from esophageal varices. The approach to acute variceal hemorrhage in children is a stepwise progression from least invasive to most invasive. Management of acute variceal bleeding is straightforward. But data on primary prophylaxis and long term management prevention of recurrent variceal bleeding in children is scarce, therefore prospective multicenter trials are needed to establish best practices.
Keywords: Portal hypertension, Variceal hemorrhage, Children