Brief Article
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World J Gastroenterol. Feb 7, 2011; 17(5): 666-670
Published online Feb 7, 2011. doi: 10.3748/wjg.v17.i5.666
Narrow-band imaging endoscopy with and without magnification in diagnosis of colorectal neoplasia
Qing-Jie Zhou, Jian-Min Yang, Bao-Ying Fei, Qi-Shun Xu, Wei-Quan Wu, Hong-Jun Ruan
Qing-Jie Zhou, Jian-Min Yang, Bao-Ying Fei, Qi-Shun Xu, Wei-Quan Wu, Hong-Jun Ruan, Department of Gastroenterology, Zhejiang Provincial People’s Hospital, Hangzhou 310014, Zhejiang Province, China
Author contributions: Zhou QJ and Yang JM contributed equally to this work; Yang JM designed the research; Yang JM, Zhou QJ, Fei BY, Xu QS, Wu WQ and Ruan HJ performed the research; Zhou QJ and Yang JM analyzed data and wrote the paper.
Correspondence to: Dr. Jian-Min Yang, Department of Gastroenterology, Zhejiang Provincial People’s Hospital, Hangzhou 310014, Zhejiang Province, China. jianminyang@hotmail.com
Telephone: +86-571-85893430 Fax: +86-571-85131448
Received: August 16, 2010
Revised: October 22, 2010
Accepted: October 29, 2010
Published online: February 7, 2011
Abstract

AIM: To evaluate the diagnostic efficacies of narrow-band imaging (NBI) endoscopy with and without high magnification in distinguishing neoplasia from non-neoplasia colorectal lesions.

METHODS: A total of 118 patients with 123 colorectal lesions examined by NBI endoscopy in the Zhejiang Provincial People’s Hospital from September 2008 to April 2010 were enrolled in this study. These lesions were classified by pit pattern and capillary pattern, and then assessed by histopathology.

RESULTS: Ten lesions not meeting the diagnostic criteria were excuded, the overall diagnostic accuracy of NBI endoscopy in distinguishing neoplasia from non-neoplasia colorectal lesions was 91.2% (103/113), and that of NBI endoscopy with and without high magnification was 93.0% (40/43) and 90.0% (63/70), respectively. Both were significantly higher than that of conventional colonoscopy reported in the literature (P < 0.05), but there was no significant difference between the two groups (P > 0.05).

CONCLUSION: Besides NBI magnifying endoscopy, NBI endoscopy without magnification may also be used to distinguish neoplasia from non-neoplasia colorectal lesions.

Keywords: Narrow-band imaging, Colorectal neoplasia, Magnifying endoscopy, Non-magnifying endoscopy, Diagnosis