Brief Article
Copyright ©2010 Baishideng. All rights reserved.
World J Gastroenterol. Jul 14, 2010; 16(26): 3287-3291
Published online Jul 14, 2010. doi: 10.3748/wjg.v16.i26.3287
Safety of same-day endoscopic ultrasound and endoscopic retrograde cholangiopancreatography under conscious sedation
Kendrick Che, Natasha Muckova, Snorri Olafsson, Wichit Srikureja
Kendrick Che, Natasha Muckova, Snorri Olafsson, Wichit Srikureja, Department of Internal Medicine, Division of Gastroenterology, Loma Linda University Medical Center, Loma Linda, CA 92354, United States
Author contributions: Srikureja W designed the research; Che K and Muckova N performed the research; Olafsson S provided the analytic tools and analyzed the data; Che KM wrote the paper.
Correspondence to: Kendrick Che, DO, Department of Internal Medicine, Division of Gastroenterology, Loma Linda University Medical Center, 11234 Anderson Street, Room 1556, Loma Linda, CA 92354, United States. kche@llu.edu
Telephone: +1-909-5584905 Fax: +1-909-5580274
Received: February 18, 2010
Revised: March 25, 2010
Accepted: April 1, 2010
Published online: July 14, 2010
Abstract

AIM: To assess the tolerability and safety of same-day tandem procedures, endoscopic ultrasound (EUS) followed by endoscopic retrograde cholangiopancreatography (ERCP) under conscious sedation.

METHODS: A retrospective review was conducted at Loma Linda University Medical Center, a tertiary-care center. All 54 patients who underwent EUS followed by ERCP (group A) from 2004 to 2006 were included in the study. A second group of 56 patients who underwent EUS only (group B), and a third group of 53 patients who underwent ERCP only (group C) during the same time period were selected consecutively as control groups for comparison.

RESULTS: Conscious sedation was used in 96% of patients in group A. Mean dosages of meperidine and midazolam used in group A were significantly higher than in group B or C. Mean recovery time in group A was not statistically longer than in group B or C. There was no significant difference in the incidence of sedation-related and procedural-related complications.

CONCLUSION: Tandem EUS/ERCP procedure can be safely performed under conscious sedation with minimal adverse events. Combined procedures, however, are associated with higher dosages of sedatives, and slightly longer recovery time.

Keywords: Conscious sedation, Safety, Same-day, Endoscopic ultrasound, Endoscopic retrograde cholangiopancreatography