Brief Article
Copyright ©2009 The WJG Press and Baishideng. All rights reserved.
World J Gastroenterol. Dec 28, 2009; 15(48): 6075-6079
Published online Dec 28, 2009. doi: 10.3748/wjg.15.6075
Wireless capsule endoscopy in detecting small-intestinal polyps in familial adenomatous polyposis
Panagiotis Katsinelos, Jannis Kountouras, Grigoris Chatzimavroudis, Christos Zavos, Ioannis Pilpilidis, Kostas Fasoulas, George Paroutoglou
Panagiotis Katsinelos, Grigoris Chatzimavroudis, Ioannis Pilpilidis, Kostas Fasoulas, George Paroutoglou, Department of Endoscopy and Motility Unit, Central Hospital, Thessaloniki 54635, Greece
Jannis Kountouras, Christos Zavos, Second Department of Internal Medicine, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki 54635, Greece
Author contributions: Katsinelos P and Kountouras J designed the study; Katsinelos P reviewed capsule videos; Katsinelos P and Kountouras J wrote the paper; Chatzimavroudis G and Fasoulas K analyzed the data; Zavos C, Pilpilidis I and Paroutoglou G reviewed the literature.
Correspondence to: Panagiotis Katsinelos, MD, PhD, Head, Department of Endoscopy and Motility Unit, Central Hospital, Ethnikis Aminis 41, Thessaloniki 54635, Greece.
Telephone: +30-2310-963341 Fax: +30-2310-210401
Received: June 11, 2009
Revised: August 7, 2009
Accepted: August 14, 2009
Published online: December 28, 2009

AIM: To detect the prevalence of small bowel polyps by wireless capsule endoscopy (WCE) in patients with familial adenomatous polyposis (FAP).

METHODS: We examined prospectively 14 patients with FAP to assess the location, size and number of small-intestinal polyps. Patients’ age, sex, years of observation after surgery, type of surgery, duodenal polyps and colorectal cancer at surgery were analyzed.

RESULTS: During WCE, polyps were detected in 9/14 (64.3%) patients. Duodenal adenomatous polyps were found in nine (64.3%) patients, and jejunal and ileal polyps in seven (50%) and eight (57.1%), respectively. The Spigelman stage of duodenal polyposis was associated with the presence of jejunal and ileal polyps. Identification of the ampulla of Vater was not achieved with WCE. Importantly, the findings of WCE had no immediate impact on the further clinical management of FAP patients. No procedure-related complications were observed in the patients.

CONCLUSION: WCE is a promising noninvasive new method for the detection of small-intestinal polyps. Further investigation is required to determine which phenotype of FAP is needed for surveillance with WCE.

Keywords: Wireless capsule endoscopy, Familial adenomatous polyposis, Intestinal polyps, Duodenal neoplasms, Adenoma