Takahara M, Miyake Y, Matsumoto K, Kawai D, Kaji E, Toyokawa T, Nakatsu M, Ando M, Hirohata M. A case of hepatic angiomyolipoma difficult to distinguish from hepatocellular carcinoma. World J Gastroenterol 2009; 15(23): 2930-2932 [PMID: 19533821 DOI: 10.3748/wjg.15.2930]
Corresponding Author of This Article
Yasuhiro Miyake, MD, Department of Molecular Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1, Shikata-cho, Okayama 700-8558, Japan. miyakeyasuhiro@hotmail.com
Article-Type of This Article
Case Report
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Masahiro Takahara, Kazuyuki Matsumoto, Daisuke Kawai, Eisuke Kaji, Tatsuya Toyokawa, Morihito Nakatsu, Masaharu Ando, Mamoru Hirohata, Department of Internal Medicine, Mitoyo General Hospital, Kagawa 769-1695, Japan
Yasuhiro Miyake, Department of Molecular Hepatology and Department of Gastroenterology & Hepatology, University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama 700-8558, Japan
Author contributions: Takahara M and Miyake Y wrote the paper; Matsumoto K, Kawai D, Kaji E, Toyokawa T, Nakatsu M and Ando M performed the patient’s care; Hirohata M supervised and approved the final manuscript.
Correspondence to: Yasuhiro Miyake, MD, Department of Molecular Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1, Shikata-cho, Okayama 700-8558, Japan. miyakeyasuhiro@hotmail.com
Telephone: +81-86-2357219
Fax: +81-86-2255991
Received: March 11, 2009 Revised: May 23, 2009 Accepted: May 30, 2009 Published online: June 21, 2009
Abstract
We report a case of hepatic angiomyolipoma with uncommon clinical features. A 56-year-old man presented with a hepatic tumor in the caudate lobe. The tumor was hypoechoic on ultrasonography, showed early-phase hyperattenuation on enhanced computed tomography and did not absorb iron on superparamagnetic iron oxide-enhanced magnetic resonance imaging. Hepatocellular carcinoma was highly suspected, and the patient underwent hepatic resection. Histologically, the tumor was mainly composed of smooth muscle cells and contained small amounts of adipose cells and blood vessels. On immunohistochemical staining, the smooth muscle cells were positive for a melanocytic cell-specific monoclonal antibody. In cases with uncommon features of angiomyolipoma, it is quite difficult to distinguish angiomyolipoma from hepatocellular carcinoma.
