Chen ZS, Meng FY, Chen XP, Liu DG, Wei L, Jiang JP, Du DF, Zhang WJ, Ming CS, Gong NQ. Combined en bloc liver/pancreas transplantation in two different patients. World J Gastroenterol 2009; 15(20): 2552-2555 [PMID: 19469010 DOI: 10.3748/wjg.15.2552]
Corresponding Author of This Article
Zhi-Shui Chen, MD, PhD, Key Laboratory of Organ Transplantation, Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, China. zschen@tjh.tjmu.edu.cn
Article-Type of This Article
Case Report
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World J Gastroenterol. May 28, 2009; 15(20): 2552-2555 Published online May 28, 2009. doi: 10.3748/wjg.15.2552
Combined en bloc liver/pancreas transplantation in two different patients
Zhi-Shui Chen, Fan-Ying Meng, Xiao-Ping Chen, Dun-Gui Liu, Lai Wei, Ji-Pin Jiang, Dun-Feng Du, Wei-Jie Zhang, Chang-Sheng Ming, Nian-Qiao Gong
Zhi-Shui Chen, Fan-Ying Meng, Xiao-Ping Chen, Dun-Gui Liu, Lai Wei, Ji-Pin Jiang, Dun-Feng Du, Wei-Jie Zhang, Chang-Sheng Ming, Nian-Qiao Gong, Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, China
Author contributions: All of the co-authors performed the research; Meng FY wrote the paper.
Correspondence to: Zhi-Shui Chen, MD, PhD, Key Laboratory of Organ Transplantation, Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, China. zschen@tjh.tjmu.edu.cn
Telephone: +86-27-83662892
Fax: +86-27-83662892
Received: February 2, 2009 Revised: April 3, 2009 Accepted: April 10, 2009 Published online: May 28, 2009
Abstract
Combined en bloc liver/pancreas transplantation (CLPT) was used primarily in the treatment of otherwise non-resectable upper abdominal malignancy. In fact, a more appropriate indication is in patients with liver disease and insulin-dependent diabetes mellitus (IDDM). Here, we report on two successful cases of CLPT at our hospital. One was a patient with non-resectable advanced liver cancer. The recipient survived for 23 mo and finally died of recurrent tumor. The other was a patient with severe biliary complication after orthotopic liver transplantation and preoperative IDDM. We performed CLPT with a modified surgical technique of preserving the native pancreas. He is currently liver-disease- and insulin-free more than 27 mo post-transplant. Based on our experience in two cases of abdominal cluster transplantation, we describe the technical details of CLPT and a modification of the surgical procedure.
