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World J Gastroenterol. Dec 28, 2008; 14(48): 7397-7399 Published online Dec 28, 2008. doi: 10.3748/wjg.14.7397
Peutz-Jeghers syndrome with small intestinal malignancy and cervical carcinoma
Lian-Jie Li, Zhi-Qing Wang, Bao-Ping Wu
Lian-Jie Li, Zhi-Qing Wang, Department of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong Province, China
Bao-Ping Wu, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong Province, China
Author contributions: Wu BP performed the endoscopic examination and the polypectomy; Li LJ and Wang ZQ collected the data; Li LJ wrote the paper.
Correspondence to: Bao-Ping Wu, MD, Huiqiao Building, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong Province, China. firstname.lastname@example.org
Telephone: +86-20-61642261 Fax: +86-20-61642494
Received: October 5, 2008 Revised: November 23, 2008 Accepted: November 30, 2008 Published online: December 28, 2008
We report a case of 30-year-old woman with Peutz-Jeghers syndrome (PJS). Because of small intestinal obstruction, she received the small intestinal polypectomy in 2001, and the pathological diagnosis was Peutz-Jeghers polyp canceration (mucinous adenocarcinoma, infiltrating full-thickness of the intestine). The patient did not feel uncomfortable after 6 mo of chemotherapy and other management. We kept a follow-up study on her and found that she suffered from cervical cancer in 2007, with a pathological diagnosis of cervical adenosquamous carcinoma.The patient presented with typical features of PJS, but without a family history. The PJS accompanied with both small intestinal and cervical malignancies has not been reported so far in the world.