Case Report
Copyright ©2008 The WJG Press and Baishideng. All rights reserved.
World J Gastroenterol. Dec 21, 2008; 14(47): 7267-7270
Published online Dec 21, 2008. doi: 10.3748/wjg.14.7267
Undifferentiated embryonal sarcoma of liver in an old female: Case report and review of the literature
Li Ma, Yue-Ping Liu, Cui-Zhi Geng, Zhi-Hui Tian, Guo-Xiang Wu, Xiao-Ling Wang
Li Ma, Cui-Zhi Geng, Department of Surgery, the Forth Hospital of Heibei Medical Univercity, No. 12, Jiangkang Road, Shijiazhuang 050011, Hebei Province, China
Yue-Ping Liu, Guo-Xiang Wu, Xiao-Ling Wang, Department of Pathology, the Forth Hospital of Heibei Medical Univercity, No. 12, Jiangkang Road, Shijiazhuang 050011, Hebei Province, China
Zhi-Hui Tian, Department of Computerized Tomographic Scan, the Forth Hospital of Heibei Medical Univercity, No. 12, Jiangkang Road, Shijiazhuang 050011, Hebei Province, China
Author contributions: Ma L, Geng CZ, Tian ZH performed the operation; Liu YP performed the immunohistochemistry; Wu GX performed the pathological detection; Ma L and Wang XL wrote the paper.
Supported by The Key Oncologic Subject Foundation of Hebei Province (No. 200552), China
Correspondence to: Xiao-Ling Wang, Department of Pathology, the Forth Hospital of Hebei Medical University, No. 12, Jiankang Road, Shijiazhuang 050011, Hebei Province, China. wangxiaoling5412@163.com
Telephone: + 86-311-8609-5374 Fax: +86-311-86077634
Received: July 17, 2008
Revised: November 12, 2008
Accepted: November 19, 2008
Published online: December 21, 2008
Abstract

The clinical characteristics of undifferentiated (embryonal) sarcoma of the liver (UESL) were investigated and the best treatment modalities were recommended. Both histology and immuno-histochemistry demonstrated the cellular features of this peculiar tumor. The tumor size was 12 cm × 9 cm × 8 cm in the right liver lobe. The patient underwent surgical resection of the tumor. The postoperative recovery was uneventful and she died eight months after diagnosis. The tumor showed mixed spindle and polygonal cells within the myxoid matrix. Some tumor cells contained eosinophilic hyaline globules that were positive for resistant diastase. Immunohistochemistry showed positive vimentin. Stellate and spindle cells were positively stained with alpha-1-antichymotrypsin (AACT) and CD68. This case indicates that UESL is not obviously differentiated in old-aged adults.

Keywords: Undifferentiated (embryonal) sarcoma, Old-aged adult, Immunohistochemistry, Liver tumor