Case Report
Copyright ©2008 The WJG Press and Baishideng. All rights reserved.
World J Gastroenterol. Aug 21, 2008; 14(31): 4964-4967
Published online Aug 21, 2008. doi: 10.3748/wjg.14.4964
A case of long survival in poorly differentiated small cell carcinoma of the pancreas
Min Sung Chung, Tae Kyung Ha, Kyeong Geun Lee, Seung Sam Paik
Min Sung Chung, Tae Kyung Ha, Kyeung Geun Lee, Department of Surgery, College of Medicine, Hanyang University, Seoul 133-792, South Korea
Seung Sam Paik, Department of Pathology, College of Medicine, Hanyang University, Seoul 133-792, South Korea
Author contributions: Chung MS designed the research; Chung MS and Ha TK wrote the paper; Lee KG revised the paper; and Paik SS analyzed the pathological figures.
Correspondence to: Dr. Kyeong Geun Lee, Department of Surgery, College of Medicine, Hanyang University, Hanyang Univ. Hospital, Haengdang 1-dong, Seongdong-gu, Seoul, South Korea. hepafel@hanyang.ac.kr
Telephone: +82-2-2290-8448 Fax: +82-2-2281-0224
Received: May 29, 2008
Revised: July 22, 2008
Accepted: July 29, 2008
Published online: August 21, 2008
Abstract

Small cell carcinoma (SCC) of the pancreas is rare. It has similar histological features to pulmonary small cell carcinoma and is equally aggressive. Most patients with SCC in the pancreas reported in case studies died within 1 year after diagnosis. We present a case of unusually long-term survival after surgery and combined chemotherapy for SCC of the pancreas. A 62-year-old woman presented with epigastric pain and jaundice. Computed tomography revealed dilated common bile duct caused by external compression of the mass in the pancreatic head. Exploratory laparotomy and pancreaticoduodenectomy (PPPD) was performed with histopathological analysis confirming a primary small cell carcinoma of the pancreas. After an uneventful postoperative recovery, the patient was treated with 6 cycles of combined chemotherapy consisting of cisplatin and ectoposide. During the follow-up, there was no evidence of recurrence and the patient has remained in a good health condition for 36 mo since the diagnosis.

Keywords: Small cell carcinoma, Pancreas, Pancreatic carcinoma, Extrapulmonary