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©2008 The WJG Press and Baishideng. All rights reserved.
World J Gastroenterol. Aug 7, 2008; 14(29): 4709-4712
Published online Aug 7, 2008. doi: 10.3748/wjg.14.4709
Published online Aug 7, 2008. doi: 10.3748/wjg.14.4709
Coexistence of small cell neuroendocrine carcinoma and villous adenoma in the ampulla of Vater
Ji-Hong Sun, Ming Chao, Guang-Qiang Zhang, Bin Li, Jian-Jun Wu, Department of Radiology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang Province, China
Shi-Zheng Zhang, Department of Radiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, Zhejiang Province, China
Author contributions: Sun JH, Chao M, Zhang SZ, Zhang GQ, Li B and Wu JJ acquired data and performed the research; Sun JH wrote the manuscript; and Chao M, Zhang SZ revised the article.
Correspondence to: Dr. Ming Chao, Department of Radiology, Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou 310009, Zhejiang Province, China. zhdfshk@hotmail.com
Telephone: +86-571-87783862
Fax: +86-571-87214631
Received: April 23, 2008
Revised: June 10, 2008
Accepted: June 17, 2008
Published online: August 7, 2008
Revised: June 10, 2008
Accepted: June 17, 2008
Published online: August 7, 2008
Abstract
Small cell neuroendocrine carcinoma of the ampulla of Vater is extremely rare and different from the common ampullary adenocarcinoma. The ampullary adenoma is also a rare neoplasm and has the potential to develop an adenocarcinoma. Their coexistence has been rarely reported in the literature. We herein describe an unusual case of a small cell neuroendocrine carcinoma associated with a villous adenoma in the ampulla of Vater with emphasis on computed tomography (CT) and histopathological findings. We also discuss their clinical, histopathological and radiological features as well as possible histogenesis.
Keywords: Small cell neuroendocrine carcinoma, Adenoma, Ampulla of Vater, Computed tomography, Histopathology