Letters To The Editor
Copyright ©2008 The WJG Press and Baishideng. All rights reserved.
World J Gastroenterol. Jul 28, 2008; 14(28): 4586-4587
Published online Jul 28, 2008. doi: 10.3748/wjg.14.4586
Ten mg dexrabeprazole daily is as effective as 20 mg dexrabeprazole daily
Rajendra Kanakia, Suresh Jain
Rajendra Kanakia, Gastroenterologist & Hepatologist, Kanakia Healthcare & Digestive Health Centre, Mumbai-400014, India
Suresh Jain, Digestive Endoscopy Clinic & A Day Care Center, Pune 411001, India
Author contributions: Kanakia R and Jain S contributed equally to this work; Kanakia R and Jain S designed and performed the research, analyzed the data and wrote the paper.
Correspondence to: Dr. Suresh Jain, Digestive Endoscopy Clinic & A Day Care Center, 103/A, Khopkar Heights, Quarter Gate Chowk, Opp. YMCA Club, Pune 411001, India. drjainsuresh@gmail.com
Telephone: +91-20-26130932
Fax: +91-20-39821019
Received: June 2, 2008
Revised: July 7, 2008
Accepted: July 14, 2008
Published online: July 28, 2008
Abstract

Ten mg dexrabeprazole daily has been shown to be more effective than 20 mg rabeprazole daily against gastroesophageal reflux disease (GERD). This report shows that the efficacy of 10 mg dexrabeprazole daily is equivalent to that of 20 mg dexrabeprazole daily against GERD. This implies that a dose of 10 mg dexrabeprazole is sufficient to block the maximum amount of proton pumps without any need to double the dose as suggested with rabeprazole.

Keywords: Dexrabeprazole, Rabeprazole, Gastroesophageal reflux disease