Rhee KH, Lee SS, Huh JR. Endoscopic ultrasonography-guided trucut biopsy for the preoperative diagnosis of peripancreatic castleman’s disease: A case report. World J Gastroenterol 2008; 14(13): 2115-2117 [PMID: 18395917 DOI: 10.3748/wjg.14.2115]
Corresponding Author of This Article
Sang Soo Lee, MD, PhD, Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, 388-1 Pungnap-2 dong, Songpa-gu, Seoul 138-736, South Korea. ssleedr@amc.seoul.kr
Article-Type of This Article
Case Report
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World J Gastroenterol. Apr 7, 2008; 14(13): 2115-2117 Published online Apr 7, 2008. doi: 10.3748/wjg.14.2115
Endoscopic ultrasonography-guided trucut biopsy for the preoperative diagnosis of peripancreatic castleman’s disease: A case report
Kyoung Hoon Rhee, Sang Soo Lee, Joo Ryung Huh
Kyoung Hoon Rhee, Sang Soo Lee, Department of Gastro-enterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul 138-736, South Korea
Joo Ryung Huh, Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul 138-736, South Korea
Author contributions: Rhee KH made the plan, data collection, preparation and wrote the paper; Lee SS made the plan, conceptualization and edited the manuscript; Huh JR analyzed the data.
Correspondence to: Sang Soo Lee, MD, PhD, Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, 388-1 Pungnap-2 dong, Songpa-gu, Seoul 138-736, South Korea. ssleedr@amc.seoul.kr
Telephone: +82-2-30103187
Fax: +82-2-4780824
Received: December 21, 2007 Revised: February 2, 2008 Published online: April 7, 2008
Abstract
Castleman’s disease (CD) of the pancreas/peripancreas is extremely rare. The recently introduced, endoscopic ultrasonography (EUS)-guided trucut biopsy (TCB) is a useful diagnostic modality for obtaining tissue samples from peripancreatic lesions. However, its role in diagnosing CD remains unknown. We report a case of localized, peripancreatic, hyaline-vascular CD biopsied using EUS. The pathology results were initially interpreted as an extranodal, marginal-zone B-cell lymphoma. However, polymerase chain reaction (PCR) study for the IgH gene rearrangement revealed a polyclonal pattern. We also reviewed the relevant literature. To our knowledge, this is the first illustrated report on EUS-TCB findings of CD with its pathology results of EUS-TCB mimicked a B-cell lymphoma.
