Case Report
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World J Gastroenterol. Dec 28, 2007; 13(48): 6603-6604
Published online Dec 28, 2007. doi: 10.3748/wjg.v13.i48.6603
Littoral-cell angioma of the spleen: A case report
Ángel Cosme, Ángel Tejada, Luis Bujanda, Manuel Vaquero, José Luis Elorza, Evelia Ojeda, Unai Goikoetxea
Ángel Cosme, Ángel Tejada, Luis Bujanda, Unai Goikoetxea, Department of Gastroenterology, Hospital Donostia, Spain
Manuel Vaquero, Department of Pathology, Hospital Donostia, Spain
José Luis Elorza, Departamet of Surgery, Hospital Donostia, Spain
Evelia Ojeda, Department of Internal Medicine, Hospital Donostia, Spain
Correspondence to: Ángel Cosme, Department of Gastroen-terology, Hospital Donostia, Paseo Beguiristain, s/n, 20014, San Sebastián (Gipuzkoa), Spain. acosme@chdo.osakidetza.net
Telephone: +34-985-943003463 Fax: +34-985-943007065
Received: July 6, 2007
Revised: October 1, 2007
Accepted: October 26, 2007
Published online: December 28, 2007
Abstract

Littoral-cell angioma (LCA) is a primary splenic vascular tumor that arises from the normal littoral cells lining the sinus channels of the splenic red pulp. We report a case of LCA of the spleen, which has been infrequently communicated in the literature. A 76-year-old man with a 2-wk history of weight loss, abdominal pain and changes in bowel habits was admitted to our hospital. Imaging studies (CT and MRI) showed multiple lesions in the spleen. Splenectomy was performed. Lining cells were positive for CD31/CD68 markers. Our case was associated with a serrated colonic adenoma. LCA is a benign vascular tumor of the spleen that needs to be included in the differential diagnosis of multiple splenic nodules.

Keywords: Littoral-cell angioma, Spleen