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World J Gastroenterol. Feb 28, 2006; 12(8): 1165-1174
Published online Feb 28, 2006. doi: 10.3748/wjg.v12.i8.1165
Etiology and consequences of thrombosis in abdominal vessels
Yusuf Bayraktar, Ozgur Harmanci
Yusuf Bayraktar, Ozgur Harmanci, Hacettepe University Faculty of Medicine, Department of Gastroenterology, 06100 Sihhiye, Ankara, Turkey
Co-correspondent: Ozgur Harmanci
Supported by Hacettepe University Office of Scientific Research Center
Correspondence to: Yusuf Bayraktar, MD, Hacettepe University Faculty of Medicine, Department of Gastroenterology, 06100 Sihhiye, Ankara, Turkey.
Telephone: +90-312-4439428 Fax:+90-312-4429429
Received: September 16, 2005
Revised: October 20, 2005
Accepted: October 29, 2005
Published online: February 28, 2006

The thrombophilia which can be either congenital or acquired in adult life has major implications in the abdominal vessels. The resulting portal vein thrombosis, Budd-Chiari syndrome and mesenteric vein thrombosis have a variety of consequences ranging from acute abdomen to chronic hepatomegaly and even totally asymptomatic patient in whom the only finding is pancytopenia. The complications like esophageal varices, portal gastropathy, ascites, severe hypersplenism, liver failure requiring liver transplantation are well known. Interesting features of collateral venous circulation showing itself as pseudocholangiocarcinoma sign and its possible clinical reflection as cholestasis are also known from a long time. The management strategies for these complications of intraabdominal vessel thrombosis are not different from their counterpart which is cirrhotic portal hypertension, but the prognosis is unquestionably better in former cases. In this review we presented and discussed the abdominal venous thrombosis, etiology and the resulting clinical pictures. There are controversial issues both in nomenclature, and management including anticoagulation problems and follow up strategies. In light of the current knowledge, we discussed some controversial issues in literature and presented our experience and our proposals about this group of patients.

Keywords: Portal vein thrombosis, Pseudocholangiocarcinoma sign, Thrombophilia, Budd-Chiari syndrome, Mesenteric vein thrombosis