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World J Gastroenterol. Feb 14, 2006; 12(6): 843-852
Published online Feb 14, 2006. doi: 10.3748/wjg.v12.i6.843
Published online Feb 14, 2006. doi: 10.3748/wjg.v12.i6.843
Cutaneous manifestations in celiac disease
L Abenavoli, L Leggio, A Ferrulli, L Vonghia, G Gasbarrini, G Addolorato, Institute of Internal Medicine, Università Cattolica del Sacro Cuore, Rome, Italy
I Proietti, R Capizzi, M Rotoli, PL Amerio, Institute of Dermatology, Università Cattolica del Sacro Cuore, Rome, Italy
Correspondence to: Giovanni Addolorato, MD, Institute of Internal Medicine, Catholic University, L.go Gemelli 8, 00168 Rome, Italy. g.addolorato@rm.unicatt.it
Telephone: +39-06-30154334 Fax: +39-06-35502775
Received: May 6, 2005
Revised: June 10, 2005
Accepted: July 28, 2005
Published online: February 14, 2006
Revised: June 10, 2005
Accepted: July 28, 2005
Published online: February 14, 2006
Abstract
Celiac disease (CD) is an autoimmune gluten-dependent enteropathy characterized by atrophy of intestinal villi that improves after gluten-free diet (GFD). CD is often associated with extra-intestinal manifestations; among them, several skin diseases are described in CD patients. The present review reports all CD-associated skin manifestations described in the literature and tries to analyze the possible mechanisms involved in this association. The opportunity to evaluate the possible presence of CD in patients affected by skin disorders is discussed.
Keywords: Celiac disease, Dermatological disease, AGA, EmA, TTG