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World J Gastroenterol. Jun 28, 2006; 12(24): 3933-3935
Published online Jun 28, 2006. doi: 10.3748/wjg.v12.i24.3933
Published online Jun 28, 2006. doi: 10.3748/wjg.v12.i24.3933
Mesenteric adenitis caused by Yersinia pseudotubercolosis in a patient subsequently diagnosed with Crohn’s disease of the terminal ileum
Maddalena Zippi, Adriana Marcheggiano, Roberta Pica, Paolo Paoluzi, Renzo Caprilli, Department of Clinical Sciences, GI Unit, Umberto I Viale del Policlinico 155, 00161, Rome, Italy
Maria Chiara Colaiacomo, Francesca Maccioni, Department of Radiological Sciences, Umberto I Viale del Policlinico 155, 00161, Rome, Italy
Giancarlo Iaiani, Department of Infectious Diseases, Umberto I Viale del Policlinico 155, 00161, Rome, Italy
Author contributions: All authors contributed equally to the work.
Correspondence to: Maddalena Zippi, Department of Clinical, Sciences Policlinico, Umberto I Viale del Policlinico 155, 00161, Rome, Italy. maddyzip@yahoo.it
Telephone: +39-60-6490335
Received: March 29, 2005
Revised: July 15, 2005
Accepted: July 28, 2005
Published online: June 28, 2006
Revised: July 15, 2005
Accepted: July 28, 2005
Published online: June 28, 2006
Abstract
Although the association between inflammatory bowel disease and gastrointestinal infections has been suggested, the mechanisms involved in the pathogenesis of Crohn’s disease (CD) are still undetermined. We report the case of a man, who presented with mesenteric adenitis initially due to a Yersinia pseudotubercolosis infection, who was later diagnosed with Crohn’s disease. This case is in keeping with recent evidence in the literature which suggests that CD is a disease linked to abnormal immune responses to enteric bacteria in genetically susceptible individuals.
Keywords: Yersinia pseudotubercolosis, Crohn’s disease, Ileitis