NasirKhan MU, Abir F, Longo W, Kozol R. Anastomotic disruption after large bowel resection. World J Gastroenterol 2006; 12(16): 2497-2504 [PMID: 16688793 DOI: 10.3748/wjg.v12.i16.2497]
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Robert A Kozol, MD, University of Connecticut, Department of Surgery, 263 Farmington Avenue, MC 3955 Farmington, CT 06030, United States. email@example.com
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Anastomotic disruption after large bowel resection
Mohammad U NasirKhan, Farshad Abir, Walter Longo, Robert Kozol
Mohammad U NasirKhan, Farshad Abir, Walter Longo, Robert Kozol, Departments of Surgery, University of Connecticut School of Medicine and Health Center, United States, Yale University School of Medicine, United States
Author contributions: All authors contributed equally to the work.
Correspondence to: Robert A Kozol, MD, University of Connecticut, Department of Surgery, 263 Farmington Avenue, MC 3955 Farmington, CT 06030, United States. firstname.lastname@example.org
Telephone: +1-860-6794801 Fax: +1-860-6791847
Received: October 4, 2005 Revised: November 1, 2005 Accepted: November 10, 2005 Published online: April 28, 2006
Anastomotic disruption is a feared and serious complication of colon surgery. Decades of research have identified factors favoring successful healing of anastomoses as well as risk factors for anastomotic disruption. However, some factors, such as the role of mechanical bowel preparation, remain controversial. Despite proper caution and excellent surgical technique, some anastomotic leaks are inevitable. The rapid identification of anastomotic leaks and the timely treatment in these cases are paramount.