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World J Gastroenterol. Apr 28, 2006; 12(16): 2497-2504
Published online Apr 28, 2006. doi: 10.3748/wjg.v12.i16.2497
Anastomotic disruption after large bowel resection
Mohammad U NasirKhan, Farshad Abir, Walter Longo, Robert Kozol
Mohammad U NasirKhan, Farshad Abir, Walter Longo, Robert Kozol, Departments of Surgery, University of Connecticut School of Medicine and Health Center, United States, Yale University School of Medicine, United States
Author contributions: All authors contributed equally to the work.
Correspondence to: Robert A Kozol, MD, University of Connecticut, Department of Surgery, 263 Farmington Avenue, MC 3955 Farmington, CT 06030, United States.
Telephone: +1-860-6794801 Fax: +1-860-6791847
Received: October 4, 2005
Revised: November 1, 2005
Accepted: November 10, 2005
Published online: April 28, 2006

Anastomotic disruption is a feared and serious complication of colon surgery. Decades of research have identified factors favoring successful healing of anastomoses as well as risk factors for anastomotic disruption. However, some factors, such as the role of mechanical bowel preparation, remain controversial. Despite proper caution and excellent surgical technique, some anastomotic leaks are inevitable. The rapid identification of anastomotic leaks and the timely treatment in these cases are paramount.

Keywords: Colon, Colectomy, Anastomosis, Surgical complications