Published online Apr 21, 2006. doi: 10.3748/wjg.v12.i15.2382
Revised: October 9, 2005
Accepted: October 10, 2005
Published online: April 21, 2006
AIM: To correlate the clinical features of treated and untreated patients with irritable bowel syndrome (IBS) to the results of skin prick test (SPT) for food and inhalant allergens.
METHODS: We recruited 105 subjects to form three different target groups: treated group (n = 44) undergoing treatment for IBS, untreated group (n = 31) meeting the Rome II criteria without treatment for IBS, control group (n = 30) with no IBS symptoms.
RESULTS: SPT results were different among the three groups in which SPT was positive in 17 (38.6%) treated patients, in 5 (16.1%) untreated patients and in 1 (3.3%) control (P < 0.01). The number of positive SPTs was greater in the IBS group than in the control group (P < 0.001). The number of positive food SPTs was higher in the treated IBS group than in the untreated IBS group (P = 0.03).
CONCLUSION: Positive food SPT is higher in IBS patients than in controls.