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World J Gastroenterol. Apr 14, 2006; 12(14): 2305-2307
Published online Apr 14, 2006. doi: 10.3748/wjg.v12.i14.2305
Published online Apr 14, 2006. doi: 10.3748/wjg.v12.i14.2305
An interesting cause of esophageal ulcer etiology: Multiple myeloma of IgG kappa subtype
Yavuz Pehlivan, Alper Sevinc, Ibrahim Sari, Murat T Gulsen, Mehmet Buyukberber, Mehmet E Kalender, Celalettin Camci, Gaziantep University, School of Medicine, Departments of Internal Medicine, Medical Oncology, Pathology, and Gastroentero-logy, Sahinbey Medical Center, Gaziantep, TR-27310, Turkey
Correspondence to: Dr. Alper Sevinc, Gaziantep University, School of Medicine, Department of Medical Oncology, Sahinbey Medical Center, Gaziantep, TR-27310, Turkey. sevinc@gantep.edu.tr
Telephone: +90-342-3601314 Fax: +90-342-3601617
Received: September 22, 2005
Revised: October 10, 2005
Accepted: November 18, 2005
Published online: April 14, 2006
Revised: October 10, 2005
Accepted: November 18, 2005
Published online: April 14, 2006
Abstract
Multiple myeloma is a neoplasm of mature and immature plasma cells. A 50-year-old woman with lumbago, dysphagia, and left arm pain was presented. Upper endoscopical examination was performed. There was an exudate-covered ulcer in the distal esophagus, located at 30-32 cm from the incisors, covering the whole mucosa. Histopathological examination of the specimens obtained from the lesion showed the involvement of plasma cells consistent with multiple myeloma of IgG kappa subtype. Esophageal involvement of multiple myeloma should be kept in mind in patients presenting with dysphagia.
Keywords: Multiple myeloma, Esophageal ulcer, Dysphagia, Endoscopy