Clinical Research
Copyright ©2005 Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jun 28, 2005; 11(24): 3735-3741
Published online Jun 28, 2005. doi: 10.3748/wjg.v11.i24.3735
Multivariate analysis of the risk for pulmonary complication after gastrointestinal surgery
Shan-Ping Jiang, Zhi-Ying Li, Li-Wen Huang, Wei Zhang, Zhi-Qiang Lu, Zhi-Yong Zheng
Shan-Ping Jiang, Zhi-Ying Li, Li-Wen Huang, Wei Zhang, Zhi-Qiang Lu, Department of Respiratory Medicine, the Second Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510120, Guangdong Province, China
Zhi-Yong Zheng, Department of Gastroenterologic Medicine, the Second Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510120, Guangdong Province, China
Author contributions: All authors contributed equally to the work.
Correspondence to: Shan-Ping Jiang, Associate Professor, Department of Respiratory Medicine, the Second Affiliated Hospital, Sun Yat-Sen University, 107 Yanjiang West Road, Guangzhou 510120, Guangdong Province, China. jiangsp@mail.china.com
Telephone: +86-20-81332441 Fax: +86-20-81332853
Received: July 5, 2004
Revised: July 6, 2004
Accepted: July 15, 2004
Published online: June 28, 2005
Abstract

AIM: To identify the risk factors for postoperative pulmonary complications (PPC) after gastrointestinal surgery.

METHODS: A total of 1002 patients undergoing gastrointestinal surgery in the Second Affiliated Hospital, Sun Yat-Sen University, during December 1999 and December 2003, were retrospectively studied.

RESULTS: The overall incidence of PPC was 22.8% (228/1002). Multivariate logistic analysis identified nine risk factors associated with PPC, including age odds ratio (OR = 1.040) history of respiratory diseases (OR = 2.976), serum albumin (OR = 0.954), chemotherapy 2 wk before operation (OR = 3.214), volume of preoperative erythrocyte transfusion (OR = 1.002), length of preoperative antibiotic therapy (OR = 1.072), intraoperative intratracheal intubation (OR = 1.002), nasogastric intubation (OR = 1.050) and postoperative mechanical ventilation (OR = 1.878). Logistic regression equation for predicting the risk of PPC was P(1) = 1/[1+e-(-3.488+ 0.039×Y+1.090×Rd+0.001×Rbc-0.047×Alb+0.002×Lii+ 0.049×Lni+0.630×Lmv+0.070×Dat+ 1.168×Ct)].

CONCLUSION: Old patients are easier to develop PPC.

Keywords: Postoperative pulmonary complications, Gastrointestinal surgery, Multivariate analysis