Nomura K, Fukumoto K, Shimizu D, Okuda T, Yoshida N, Kamitsuji Y, Matsumoto Y, Konishi H, Ueda Y, Horiike S, Okanoue T, Taniwaki M. Pseudomembranous colitis presenting as acute colonic obstruction without diarrhea in a patient with gastric Burkitt lymphoma. World J Gastroenterol 2005; 11(17): 2681-2683 [PMID: 15849835 DOI: 10.3748/wjg.v11.i17.2681]
Corresponding Author of This Article
Kenichi Nomura, MD, PhD, Department of Molecular Hematology and Oncology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-0841, Japan. nomuken@koto.kpu-m.ac.jp
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Kenichi Nomura, Kohei Fukumoto, Daisuke Shimizu, Yosuke Matsumoto, Shigeo Horiike, Masafumi Taniwaki, Department of Molecular Hematology and Oncology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan
Yuri Kamitsuji, Department of Inflammation and Immunology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan
Takashi Okuda, Naohisa Yoshida, Hideyuki Konishi, Takeshi Okanoue, Department of Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan
Yuji Ueda, Division of Digestive Surgery, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan
Masafumi Taniwaki, Department of Clinical Molecular Genetics and Laboratory Medicine, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan
Author contributions: All authors contributed equally to the work.
Correspondence to: Kenichi Nomura, MD, PhD, Department of Molecular Hematology and Oncology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-0841, Japan. nomuken@koto.kpu-m.ac.jp
Telephone: +81-75-251-5521 Fax: +81-75-251-0710
Received: September 21, 2004 Revised: September 22, 2004 Accepted: December 1, 2004 Published online: May 7, 2005
Abstract
Pseudomembranous colitis (PMC) usually manifests as fever and diarrhea in hospitalized patients treated with systemic antibiotics. We described a case of PMC with intestinal obstruction but without diarrhea. A 60-year-old man was hospitalized for chemotherapy for the treatment of Burkitt lymphoma of the stomach. The patient became febrile and complained of crampy abdominal pain during the post-chemotherapy nadir. Plain abdominal radiography showed some intestinal gas and niveau. Because stool cytotoxin assay for clostridium difficile was positive and colon fiberscopic examination showed a pseudomembrane at the left side of the colon, and a diagnosis of PMC was made. Treatment with intracolonic vancomycin administration by colonoscopy and nasoileus tube was successful. Physicians should take into account the possibility of bowel obstruction due to PMC occurring in patients undergoing chemotherapy and perform emergency colonoscopy examination of suspected cases.
