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For: Choi S, Choi JJ, Jun JY, Koh JW, Kim SH, Kim DH, Pyo MY, Choi S, Son JP, Lee I, Son M, Jin M. Induction of pacemaker currents by DA-9701, a prokinetic agent, in interstitial cells of Cajal from murine small intestine. Mol Cells 2009;27:307-12. [PMID: 19326077 DOI: 10.1007/s10059-009-0039-6] [Citation(s) in RCA: 20] [Impact Index Per Article: 1.3] [Reference Citation Analysis] [What about the content of this article? (0)] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/04/2008] [Revised: 12/09/2008] [Accepted: 12/26/2008] [Indexed: 12/16/2022]  Open
Number Cited by Other Article(s)
1
Gao P, Wang L, Chen Y, Yang X, Chen X, Yue C, Wu T, Jiang T, Wu H, Tang L, Wang Z. Pharbitidis Semen: A review of botany, traditional uses, phytochemistry, pharmacology, and toxicology. JOURNAL OF ETHNOPHARMACOLOGY 2023;314:116634. [PMID: 37178984 DOI: 10.1016/j.jep.2023.116634] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Subscribe] [Scholar Register] [Received: 01/31/2023] [Revised: 04/17/2023] [Accepted: 05/11/2023] [Indexed: 05/15/2023]
2
Lee JY, Kim N, Yoon H, Shin CM, Park YS, Lee DH. A Randomized, Double-Blinded, Placebo-controlled Study to Evaluate the Efficacy and Safety of DA-9701 (Motilitone) in Patients With Functional Dyspepsia and Constipation-type Irritable Bowel Syndrome Overlap: A Pilot Study. J Neurogastroenterol Motil 2022;28:265-275. [PMID: 35232894 PMCID: PMC8978125 DOI: 10.5056/jnm20236] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.7] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 10/18/2020] [Revised: 03/30/2021] [Accepted: 05/17/2021] [Indexed: 11/20/2022]  Open
3
Effect of DA-9701 on the Gastrointestinal Motility in the Streptozotocin-Induced Diabetic Mice. J Clin Med 2021;10:jcm10225282. [PMID: 34830563 PMCID: PMC8623860 DOI: 10.3390/jcm10225282] [Citation(s) in RCA: 3] [Impact Index Per Article: 0.8] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/29/2021] [Revised: 11/04/2021] [Accepted: 11/08/2021] [Indexed: 12/11/2022]  Open
4
Choi J, Lee J, Cho JW, Koh S, Yang YS, Yoo D, Shin C, Kim HT. Double-Blind, Randomized, Placebo-Controlled Trial of DA-9701 in Parkinson's Disease: PASS-GI Study. Mov Disord 2020;35:1966-1976. [PMID: 32761955 PMCID: PMC7754502 DOI: 10.1002/mds.28219] [Citation(s) in RCA: 5] [Impact Index Per Article: 1.0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/12/2020] [Revised: 05/17/2020] [Accepted: 06/24/2020] [Indexed: 01/12/2023]  Open
5
Jin M, Son M. DA-9701 (Motilitone): A Multi-Targeting Botanical Drug for the Treatment of Functional Dyspepsia. Int J Mol Sci 2018;19:ijms19124035. [PMID: 30551633 PMCID: PMC6321359 DOI: 10.3390/ijms19124035] [Citation(s) in RCA: 8] [Impact Index Per Article: 1.1] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/09/2018] [Revised: 12/07/2018] [Accepted: 12/07/2018] [Indexed: 12/12/2022]  Open
6
Kim SY, Woo HS, Kim KO, Choi SH, Kwon KA, Chung JW, Kim YJ, Kim JH, Kim SJ, Park DK. DA-9701 improves colonic transit time and symptoms in patients with functional constipation: A prospective study. J Gastroenterol Hepatol 2017;32:1943-1948. [PMID: 28431454 DOI: 10.1111/jgh.13807] [Citation(s) in RCA: 8] [Impact Index Per Article: 1.0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 02/10/2017] [Revised: 03/24/2017] [Accepted: 04/13/2017] [Indexed: 12/15/2022]
7
Jung HJ, Kang JH, Choi S, Son YK, Lee KR, Seong JK, Kim SY, Oh SH. Pharbitis Nil (PN) induces apoptosis and autophagy in lung cancer cells and autophagy inhibition enhances PN-induced apoptosis. JOURNAL OF ETHNOPHARMACOLOGY 2017;208:253-263. [PMID: 28729229 DOI: 10.1016/j.jep.2017.07.020] [Citation(s) in RCA: 16] [Impact Index Per Article: 2.0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Subscribe] [Scholar Register] [Received: 05/02/2017] [Revised: 07/10/2017] [Accepted: 07/15/2017] [Indexed: 06/07/2023]
8
Liu Q, Bi DY, Chen W, Wen WN, Chen W, Liu X, Chang XR, Zhang GS, Yuan ZY. Effect of Tongxie Yaofang on gastrointestinal motility, ultrastructure of interstitial cells of cajal and connexin 43 expression in rats with functional dyspepsia. Shijie Huaren Xiaohua Zazhi 2017;25:974-982. [DOI: 10.11569/wcjd.v25.i11.974] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.1] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 02/06/2023]  Open
9
Lee SP, Lee OY, Lee KN, Lee HL, Choi HS, Yoon BC, Jun DW. Effect of DA-9701, a Novel Prokinetic Agent, on Post-operative Ileus in Rats. J Neurogastroenterol Motil 2017;23:109-116. [PMID: 27832682 PMCID: PMC5216641 DOI: 10.5056/jnm16003] [Citation(s) in RCA: 6] [Impact Index Per Article: 0.8] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 01/08/2016] [Revised: 05/23/2016] [Accepted: 10/11/2016] [Indexed: 12/13/2022]  Open
10
Choi MG, Rhee PL, Park H, Lee OY, Lee KJ, Choi SC, Seol SY, Chun HJ, Rew JS, Lee DH, Song GA, Jung HY, Jeong HY, Sung IK, Lee JS, Lee ST, Kim SK, Shin YW. Randomized, Controlled, Multi-center Trial: Comparing the Safety and Efficacy of DA-9701 and Itopride Hydrochloride in Patients With Functional Dyspepsia. J Neurogastroenterol Motil 2015;21:414-22. [PMID: 26130637 PMCID: PMC4496904 DOI: 10.5056/jnm14117] [Citation(s) in RCA: 25] [Impact Index Per Article: 2.5] [Reference Citation Analysis] [Abstract] [Key Words] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 10/08/2014] [Revised: 12/29/2014] [Accepted: 01/07/2015] [Indexed: 01/19/2023]  Open
11
Ahn TS, Kim DG, Hong NR, Park HS, Kim H, Ha KT, Jeon JH, So I, Kim BJ. Effects of Schisandra chinensis extract on gastrointestinal motility in mice. JOURNAL OF ETHNOPHARMACOLOGY 2015;169:163-169. [PMID: 25862968 DOI: 10.1016/j.jep.2015.03.071] [Citation(s) in RCA: 11] [Impact Index Per Article: 1.1] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Subscribe] [Scholar Register] [Received: 08/21/2014] [Revised: 03/02/2015] [Accepted: 03/13/2015] [Indexed: 06/04/2023]
12
Jung JW, Kwon YS, Jeong JS, Son M, Kang HE. Pharmacokinetics and Brain Distribution of Tetrahydropalmatine and Tetrahydroberberine after Oral Administration of DA-9701, a New Botanical Gastroprokinetic Agent, in Rats. Biol Pharm Bull 2015;38:285-91. [DOI: 10.1248/bpb.b14-00678] [Citation(s) in RCA: 4] [Impact Index Per Article: 0.4] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/22/2022]
13
Jung JW, Choi MR, Kwon YS, Jeong JS, Son M, Kang HE. Gender differences in corydaline pharmacokinetics in rats. Xenobiotica 2014;45:456-63. [DOI: 10.3109/00498254.2014.988772] [Citation(s) in RCA: 6] [Impact Index Per Article: 0.5] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 12/19/2022]
14
Hwang MW, Lee JH, Kim BJ. Carthami Flos Depolarizes the Interstitial Cells of Cajal and Increases the Motility in Gastrointestinal Tract. INT J PHARMACOL 2014;10:248-257. [DOI: 10.3923/ijp.2014.248.257] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/15/2022]
15
Kim ER, Min BH, Lee TH, Son M, Rhee PL. Effect of DA-9701 on colorectal distension-induced visceral hypersensitivity in a rat model. Gut Liver 2014;8:388-93. [PMID: 25071903 PMCID: PMC4113047 DOI: 10.5009/gnl.2014.8.4.388] [Citation(s) in RCA: 7] [Impact Index Per Article: 0.6] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 01/12/2013] [Revised: 05/22/2013] [Accepted: 07/07/2013] [Indexed: 12/13/2022]  Open
16
Jung JW, Kim JM, Jeong JS, Son M, Lee HS, Lee MG, Kang HE. Pharmacokinetics of chlorogenic acid and corydaline in DA-9701, a new botanical gastroprokinetic agent, in rats. Xenobiotica 2014;44:635-43. [PMID: 24417753 DOI: 10.3109/00498254.2013.874610] [Citation(s) in RCA: 14] [Impact Index Per Article: 1.3] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 12/20/2022]
17
Kim BJ. Shengmaisan regulates pacemaker potentials in interstitial cells of cajal in mice. J Pharmacopuncture 2013;16:36-42. [PMID: 25780681 PMCID: PMC4331980 DOI: 10.3831/kpi.2013.16.025] [Citation(s) in RCA: 13] [Impact Index Per Article: 1.1] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/10/2013] [Accepted: 11/03/2013] [Indexed: 12/17/2022]  Open
18
Kwon YS, Son M. DA-9701: A New Multi-Acting Drug for the Treatment of Functional Dyspepsia. Biomol Ther (Seoul) 2013;21:181-9. [PMID: 24265862 PMCID: PMC3830115 DOI: 10.4062/biomolther.2012.096] [Citation(s) in RCA: 23] [Impact Index Per Article: 1.9] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/07/2012] [Revised: 03/12/2013] [Accepted: 03/14/2013] [Indexed: 12/17/2022]  Open
19
Lee SP, Lee KN, Lee OY, Lee HL, Jun DW, Yoon BC, Choi HS, Hwang SJ, Lee SE. Effects of DA-9701, a novel prokinetic agent, on phosphorylated extracellular signal-regulated kinase expression in the dorsal root ganglion and spinal cord induced by colorectal distension in rats. Gut Liver 2013;8:140-7. [PMID: 24672654 PMCID: PMC3964263 DOI: 10.5009/gnl.2014.8.2.140] [Citation(s) in RCA: 6] [Impact Index Per Article: 0.5] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 03/16/2013] [Revised: 04/11/2013] [Accepted: 04/15/2013] [Indexed: 12/13/2022]  Open
20
Kim BJ, Kim HW, Lee GS, Choi S, Jun JY, So I, Kim SJ. Poncirus trifoliate fruit modulates pacemaker activity in interstitial cells of Cajal from the murine small intestine. JOURNAL OF ETHNOPHARMACOLOGY 2013;149:668-675. [PMID: 23911946 DOI: 10.1016/j.jep.2013.07.017] [Citation(s) in RCA: 17] [Impact Index Per Article: 1.4] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Subscribe] [Scholar Register] [Received: 02/27/2013] [Revised: 07/02/2013] [Accepted: 07/11/2013] [Indexed: 06/02/2023]
21
Kim JN, Song HJ, Lim B, Kwon YK, Kim BJ. Modulation of pacemaker potentials by pyungwi-san in interstitial cells of cajal from murine small intestine: pyungwi-san and interstitial cells of cajal. J Pharmacopuncture 2013;16:43-49. [PMID: 25780661 PMCID: PMC4331954 DOI: 10.3831/kpi.2013.16.003] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.1] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/06/2012] [Accepted: 11/28/2012] [Indexed: 11/09/2022]  Open
22
Hwang MW, Kim JN, Song HJ, Lim B, Kwon YK, Kim BJ. Effects of Lizhong Tang on cultured mouse small intestine interstitial cells of Cajal. World J Gastroenterol 2013;19:2249-2255. [PMID: 23599652 PMCID: PMC3627890 DOI: 10.3748/wjg.v19.i14.2249] [Citation(s) in RCA: 7] [Impact Index Per Article: 0.6] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 11/12/2012] [Revised: 02/06/2013] [Accepted: 02/08/2013] [Indexed: 02/06/2023]  Open
23
Effect of a New Prokinetic Agent DA-9701 Formulated with Corydalis Tuber and Pharbitidis Semen on Cytochrome P450 and UDP-Glucuronosyltransferase Enzyme Activities in Human Liver Microsomes. EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE 2012;2012:650718. [PMID: 22548118 PMCID: PMC3323859 DOI: 10.1155/2012/650718] [Citation(s) in RCA: 7] [Impact Index Per Article: 0.5] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 11/17/2011] [Accepted: 01/02/2012] [Indexed: 12/13/2022]
24
Lee TH, Son M, Kim SY. Effects of corydaline from Corydalis tuber on gastric motor function in an animal model. Biol Pharm Bull 2011;33:958-62. [PMID: 20522959 DOI: 10.1248/bpb.33.958] [Citation(s) in RCA: 37] [Impact Index Per Article: 2.6] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/22/2022]
25
Wang ZY, Xu WX. Advances in research on pacemaking function of gastrointestinal smooth muscle cells. Shijie Huaren Xiaohua Zazhi 2010;18:319-323. [DOI: 10.11569/wcjd.v18.i4.319] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.1] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 02/06/2023]  Open
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