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For: Cui Y, Xu HF, Liu MY, Xu YJ, He JC, Zhou Y, Cang SD. Mechanism of exosomal microRNA-224 in development of hepatocellular carcinoma and its diagnostic and prognostic value. World J Gastroenterol 2019; 25(15): 1890-1898 [PMID: 31057302 DOI: 10.3748/wjg.v25.i15.1890]
URL: https://www.wjgnet.com/1007-9327/full/v25/i15/1890.htm
Number Citing Articles
1
Yuan Li, Silei Sui, Ajay Goel. Extracellular vesicles associated microRNAs: Their biology and clinical significance as biomarkers in gastrointestinal cancers. Seminars in Cancer Biology 2024; 99 doi: 10.1016/j.semcancer.2024.02.001
2
Chengyu Mao, Dongjiu Li, En Zhou, Erhe Gao, Tiantian Zhang, Shufang Sun, Lin Gao, Yuqi Fan, Changqian Wang. Extracellular vesicles from anoxia preconditioned mesenchymal stem cells alleviate myocardial ischemia/reperfusion injury. Aging 2021; 13(4) doi: 10.18632/aging.202611
3
Dongjie Xu, Kaili Di, Boyue Fan, Jie Wu, Xinrui Gu, Yifan Sun, Adeel Khan, Peng Li, Zhiyang Li. MicroRNAs in extracellular vesicles: Sorting mechanisms, diagnostic value, isolation, and detection technology. Frontiers in Bioengineering and Biotechnology 2022; 10 doi: 10.3389/fbioe.2022.948959
4
. Advances in Clinical Chemistry 2021; 101 doi: 10.1016/bs.acc.2020.06.006
5
Gang Liu, Xiao-Ming Yin. The Role of Extracellular Vesicles in Liver Pathogenesis. The American Journal of Pathology 2022; 192(10) doi: 10.1016/j.ajpath.2022.06.007
6
Miaoguo Cai, Wei Shao, Huijun Yu, Ye Hong, Lili Shi. <p>Paeonol Inhibits Cell Proliferation, Migration and Invasion and Induces Apoptosis in Hepatocellular Carcinoma by Regulating miR-21-5p/KLF6 Axis</p>. Cancer Management and Research 2020;  doi: 10.2147/CMAR.S254485
7
Malgorzata Czystowska-Kuzmicz, Theresa L. Whiteside. The potential role of tumor-derived exosomes in diagnosis, prognosis, and response to therapy in cancer. Expert Opinion on Biological Therapy 2021; 21(2) doi: 10.1080/14712598.2020.1813276
8
Wenbin Ji, Qunfeng Wang, Jian Yang. LncRNA HOXD-AS1 promotes the metastasis of human hepatocellular carcinoma via modulating miR-326/SLC27A4. Cancer Cell International 2020; 20(1) doi: 10.1186/s12935-020-01217-8
9
Ana Špilak, Andreas Brachner, Ulrike Kegler, Winfried Neuhaus, Christa Noehammer. Implications and pitfalls for cancer diagnostics exploiting extracellular vesicles. Advanced Drug Delivery Reviews 2021; 175 doi: 10.1016/j.addr.2021.05.029
10
Qin Han, Mengchen Wang, Xi Dong, Fei Wei, Yun Luo, Xiaobo Sun. Non-coding RNAs in hepatocellular carcinoma: Insights into regulatory mechanisms, clinical significance, and therapeutic potential. Frontiers in Immunology 2022; 13 doi: 10.3389/fimmu.2022.985815
11
Shuyue Yang, Jiaxin Wang, Shidong Wang, Anni Zhou, Guiping Zhao, Peng Li. Roles of small extracellular vesicles in the development, diagnosis and possible treatment strategies for hepatocellular carcinoma (Review). International Journal of Oncology 2022; 61(2) doi: 10.3892/ijo.2022.5381
12
Sara Thietart, Pierre-Emmanuel Rautou. Extracellular vesicles as biomarkers in liver diseases: A clinician's point of view. Journal of Hepatology 2020; 73(6) doi: 10.1016/j.jhep.2020.07.014
13
Xiaona Lu, Yuyao Li, Yue Li, Xuemei Zhang, Jia Shi, Hai Feng, Yueqiu Gao, Zhuo Yu. Advances of multi-omics applications in hepatic precancerous lesions and hepatocellular carcinoma: The role of extracellular vesicles. Frontiers in Molecular Biosciences 2023; 10 doi: 10.3389/fmolb.2023.1114594
14
Minhua Wu, Xubin Deng, Yu Zhong, Li Hu, Xiujuan Zhang, Yanqin Liang, Xiaofang Li, Xiaoxia Ye. MafF Is Regulated via the circ-ITCH/miR-224-5p Axis and Acts as a Tumor Suppressor in Hepatocellular Carcinoma. Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics 2020; 28(3) doi: 10.3727/096504020X15796890809840
15
Asmit Das, Sidhanti Nyahatkar, Swarup Sonar, Ketki Kalele, Vetriselvan Subramaniyan. Unlocking the potential of exosomes: A new frontier in liver cancer liquid biopsy. The Journal of Liquid Biopsy 2024; 6 doi: 10.1016/j.jlb.2024.100166
16
Bandar Almutairy, Mohammad S. Alzahrani, Dania S. Waggas, Hashem O. Alsaab. Particular exosomal micro-RNAs and gastrointestinal (GI) cancer cells' roles: Current theories. Experimental Cell Research 2024; 442(2) doi: 10.1016/j.yexcr.2024.114278
17
Manica Negahdaripour, Hajar Owji, Sedigheh Eskandari, Mozhdeh Zamani, Bahareh Vakili, Navid Nezafat. Small extracellular vesicles (sEVs): discovery, functions, applications, detection methods and various engineered forms. Expert Opinion on Biological Therapy 2021; 21(3) doi: 10.1080/14712598.2021.1825677
18
Fenfen Guo, Hong Li, Jingjing Wang, Jiangfeng Wang, Jinling Zhang, Fanfang Kong, Zemin Zhang, Jinbao Zong. MicroRNAs in Hepatocellular Carcinoma: Insights into Regulatory Mechanisms, Clinical Significance, and Therapeutic Potential. Cancer Management and Research 2024;  doi: 10.2147/CMAR.S477698
19
Omar M.K. Ahmad, Elizabeth A. Rao, Tony Y. Hu. Cancer Theranostics, Second Edition. 2026;  doi: 10.1016/B978-0-443-22253-5.00022-4
20
Bahare Niknam, Kaveh Baghaei, Seyed Mahmoud Hashemi, Behzad Hatami, Mohammad Reza Zali, Davar Amani. Human Wharton’s jelly mesenchymal stem cells derived-exosomes enriched by miR-124 promote an anti-fibrotic response in an experimental model of liver fibrosis. International Immunopharmacology 2023; 119 doi: 10.1016/j.intimp.2023.110294
21
Devis Pascut, Muhammad Yogi Pratama, Niem V.T. Vo, Rina Masadah, Claudio Tiribelli. The Crosstalk between Tumor Cells and the Microenvironment in Hepatocellular Carcinoma: The Role of Exosomal microRNAs and Their Clinical Implications. Cancers 2020; 12(4) doi: 10.3390/cancers12040823
22
. Advances in Clinical Chemistry 2022; 110 doi: 10.1016/bs.acc.2022.06.004
23
Le Cheng, Limin Zhang, Xiaoxiao Wang, Yufei Wang, Jiahui Yu, Mengnan Li, Zhaowu Ma, Paul Chi-Lui Ho, Xiaoguang Chen, Lingzhi Wang, Gautam Sethi, Boon-Cher Goh. Extracellular vesicles in the HCC microenvironment: Implications for therapy and biomarkers. Pharmacological Research 2024; 209 doi: 10.1016/j.phrs.2024.107419
24
Lin Li, Lili Zhang, Katelynn C. Montgomery, Li Jiang, Christopher J. Lyon, Tony Y. Hu. Advanced technologies for molecular diagnosis of cancer: State of pre-clinical tumor-derived exosome liquid biopsies. Materials Today Bio 2023; 18 doi: 10.1016/j.mtbio.2022.100538
25
Qian Zhang, Hanlin Li, Yang Liu, Jian Li, Chunling Wu, Hua Tang. Exosomal Non-Coding RNAs: New Insights into the Biology of Hepatocellular Carcinoma. Current Oncology 2022; 29(8) doi: 10.3390/curroncol29080427
26
Ruikang Ming, Xuemeng Gao, Xiaoying Hu, Zhihan Yang, Chunzi Liang, Guo-Jun Zhang, Baoping Luo, Shi-Bo Cheng, Yu-Tao Li. Engineering Extracellular Vesicle Isolation and Sensing Technologies for Hepatocellular Carcinoma Diagnostics. ACS Sensors 2026; 11(9) doi: 10.1021/acssensors.6c01215
27
Lauren A. Newman, Kate Muller, Andrew Rowland. Circulating cell-specific extracellular vesicles as biomarkers for the diagnosis and monitoring of chronic liver diseases. Cellular and Molecular Life Sciences 2022; 79(5) doi: 10.1007/s00018-022-04256-8
28
Mohammed H. Abu-Alghayth, Adil Abalkhail, Ali Hazazi, Yara Alyahyawi, Osama Abdulaziz, Abdulaziz Alsharif, Somia A. Nassar, Bashir Ibrahim A. Omar, Sultan F. Alqahtani, Humood Al Shmrany, Farhan R. Khan. MicroRNAs and long non-coding RNAs In T-cell lymphoma: Mechanisms, pathway, therapeutic opportunities. Pathology - Research and Practice 2025; 266 doi: 10.1016/j.prp.2024.155769
29
Chen Wang, Jinwen Liu, Yongmin Yan, Youwen Tan, Liu Jinhui. Role of Exosomes in Chronic Liver Disease Development and Their Potential Clinical Applications. Journal of Immunology Research 2022; 2022 doi: 10.1155/2022/1695802
30
Sandeep Sisodiya, Vishakha Kasherwal, Asiya Khan, Bishnudeo Roy, Anjana Goel, Sandeep Kumar, Nazneen Arif, Pranay Tanwar, Showket Hussain. Liquid Biopsies: Emerging role and clinical applications in solid tumours. Translational Oncology 2023; 35 doi: 10.1016/j.tranon.2023.101716
31
Chen Li, Yu-Qing Ni, Hui Xu, Qun-Yan Xiang, Yan Zhao, Jun-Kun Zhan, Jie-Yu He, Shuang Li, You-Shuo Liu. Roles and mechanisms of exosomal non-coding RNAs in human health and diseases. Signal Transduction and Targeted Therapy 2021; 6(1) doi: 10.1038/s41392-021-00779-x
32
Zhen Fang, Yixuan Ding, Zhigang Xue, Peijuan Li, Jia Li, Fei Li. Roles of exosomes as drug delivery systems in cancer immunotherapy: a mini-review. Discover Oncology 2022; 13(1) doi: 10.1007/s12672-022-00539-5
33
Suvendra N. Bhattacharyya, Syamantak Ghosh, Sourav Hom Choudhury, Kamalika Mukherjee. Mechanisms of microRNA export in mammalian cells: From random release to selective secretion. Journal of Biological Chemistry 2026; 302(8) doi: 10.1016/j.jbc.2026.113299
34
Sophie Schlosser, Deniz Tümen, Barbara Volz, Katja Neumeyer, Niklas Egler, Claudia Kunst, Hauke Christian Tews, Stephan Schmid, Arne Kandulski, Martina Müller, Karsten Gülow. HCC biomarkers – state of the old and outlook to future promising biomarkers and their potential in everyday clinical practice. Frontiers in Oncology 2022; 12 doi: 10.3389/fonc.2022.1016952
35
Xiaomei Yi, Jie Chen, Defa Huang, Shuo Feng, Tong Yang, Zhengzhe Li, Xiaoxing Wang, Minghong Zhao, Jiyang Wu, Tianyu Zhong. Current perspectives on clinical use of exosomes as novel biomarkers for cancer diagnosis. Frontiers in Oncology 2022; 12 doi: 10.3389/fonc.2022.966981
36
Zhihua Zuo, Miyuan Yang, Xiushan Yin, Wei Tang, Lijun Du, Yongcan Guo. The role of exosomal microRNAs in detecting hepatocellular carcinoma: A systematic review and meta-analysis. Clinica Chimica Acta 2026; 591 doi: 10.1016/j.cca.2026.121143
37
Deniz Tümen, Philipp Heumann, Karsten Gülow, Cagla-Nur Demirci, Lidia-Sabina Cosma, Martina Müller, Arne Kandulski. Pathogenesis and Current Treatment Strategies of Hepatocellular Carcinoma. Biomedicines 2022; 10(12) doi: 10.3390/biomedicines10123202
38
Mahsa Ghasemian-Irani, Shabnam Babaei, Tohid Kazemi. Exosomes in hepatocellular carcinoma: involvement in reprogramming the tumor microenvironment for immune evasion, metastasis, angiogenesis, and drug resistance. Cell Cycle 2025; 24(21-24) doi: 10.1080/15384101.2025.2583289
39
Mudasir A. Kumar, Sadaf K. Baba, Hana Q. Sadida, Sara Al. Marzooqi, Jayakumar Jerobin, Faisal H. Altemani, Naseh Algehainy, Mohammad A. Alanazi, Abdul-Badi Abou-Samra, Rakesh Kumar, Ammira S. Al-Shabeeb Akil, Muzafar A. Macha, Rashid Mir, Ajaz A. Bhat. Extracellular vesicles as tools and targets in therapy for diseases. Signal Transduction and Targeted Therapy 2024; 9(1) doi: 10.1038/s41392-024-01735-1
40
Sana Khurshid Baba, Sadaf Khursheed Baba, Rashid Mir, Imadeldin Elfaki, Naseh Algehainy, Mohammad Fahad Ullah, Jameel Barnawi, Faisal H. Altemani, Mohammad Alanazi, Syed Khalid Mustafa, Tariq Masoodi, Ammira S. Alshabeeb Akil, Ajaz A. Bhat, Muzafar A. Macha. Long non-coding RNAs modulate tumor microenvironment to promote metastasis: novel avenue for therapeutic intervention. Frontiers in Cell and Developmental Biology 2023; 11 doi: 10.3389/fcell.2023.1164301
41
Serena Lucotti, Candia M Kenific, Haiying Zhang, David Lyden. Extracellular vesicles and particles impact the systemic landscape of cancer. The EMBO Journal 2022; 41(18) doi: 10.15252/embj.2021109288
42
Abdelrahman M. Attia, Mohammad Saeid Rezaee-Zavareh, Soo Young Hwang, Naomy Kim, Hasmik Adetyan, Tamar Yalda, Pin-Jung Chen, Ekaterina K. Koltsova, Ju Dong Yang. Novel Biomarkers for Early Detection of Hepatocellular Carcinoma. Diagnostics 2024; 14(20) doi: 10.3390/diagnostics14202278
43
Duo Zuo, Jiawei Xiao, Haohua An, Yongzi Chen, Jianhua Li, Xiaohui Yang, Xia Wang, Li Ren. Screening for Lipid-Metabolism-Related Genes and Identifying the Diagnostic Potential of ANGPTL6 for HBV-Related Early-Stage Hepatocellular Carcinoma. Biomolecules 2022; 12(11) doi: 10.3390/biom12111700
44
Yusra Zarlashat, Shahid Ullah Khan, Muneeb Ullah, Alia Ambreen, Muhammad Mujahid, Muhammad N. Ullah, Muhammad K. Iqbal, Muhammad Abid, Hifsa Khan, Hassan Mushtaq, Khalil ur Rehman, Dilfaraz Khan, Mostafa M. Gouda. MicroRNAs in hepatocellular carcinoma: Diagnostic, therapeutic, and prognostic insights: A comprehensive review. Genes & Diseases 2026;  doi: 10.1016/j.gendis.2026.102419
45
Dongdong Xue, Jingzhao Han, Yifan Liu, Hongfang Tuo, Yanhui Peng. Current perspectives on exosomes in the diagnosis and treatment of hepatocellular carcinoma (review). Cancer Biology & Therapy 2021; 22(4) doi: 10.1080/15384047.2021.1898728
46
47
Qing Fan, Yue Yu, Yueling Zhou, Sheng Zhang, Chunli Wu. An emerging role of radiation‑induced exosomes in hepatocellular carcinoma progression and radioresistance (Review). International Journal of Oncology 2022; 60(4) doi: 10.3892/ijo.2022.5336
48
Soudeh Ghafouri-Fard, Kasra Honarmand Tamizkar, Bashdar Mahmud Hussen, Mohammad Taheri. MicroRNA signature in liver cancer. Pathology - Research and Practice 2021; 219 doi: 10.1016/j.prp.2021.153369
49
Giuseppa Augello, Alessandra Cusimano, Melchiorre Cervello, Antonella Cusimano. Extracellular Vesicle-Related Non-Coding RNAs in Hepatocellular Carcinoma: An Overview. Cancers 2024; 16(7) doi: 10.3390/cancers16071415
50
Yi Lv, Xiujuan Sun. Role of miRNA in pathogenesis, diagnosis, and prognosis in hepatocellular carcinoma. Chemical Biology & Drug Design 2024; 103(1) doi: 10.1111/cbdd.14352
51
Sima Heidarzadeh-Asl, Fatah Kashanchi, Reza Jafari. The Immunomodulatory Roles of Extracellular Vesicles in the Pathogenesis of Virus-Related Cancers. Viral Immunology 2026; 39(2) doi: 10.1177/08828245251413728
52
Xiaochun Jin, Ying Zhang, Hui Wang, Youtao Zhang. Expression and Clinical Values of Serum miR-155 and miR-224 in Chinese Patients with HCV Infection. International Journal of General Medicine 2022;  doi: 10.2147/IJGM.S344345
53
Ming-Cheng Guan, Wei Ouyang, Ming-Da Wang, Lei Liang, Na Li, Ting-Ting Fu, Feng Shen, Wan-Yee Lau, Qiu-Ran Xu, Dong-Sheng Huang, Hong Zhu, Tian Yang. Biomarkers for hepatocellular carcinoma based on body fluids and feces. World Journal of Gastrointestinal Oncology 2021; 13(5): 351-365 doi: 10.4251/wjgo.v13.i5.351
54
Ezhilarasan Devaraj, Elumalai Perumal, Raghunandhakumar Subramaniyan, Najimi Mustapha. Liver fibrosis: Extracellular vesicles mediated intercellular communication in perisinusoidal space. Hepatology 2022; 76(1) doi: 10.1002/hep.32239
55
Chantell Payton, Lisa Y. Pang, Mark Gray, David J. Argyle. Exosomes Derived from Radioresistant Breast Cancer Cells Promote Therapeutic Resistance in Naïve Recipient Cells. Journal of Personalized Medicine 2021; 11(12) doi: 10.3390/jpm11121310
56
Khalid Otmani, Redouane Rouas, Philippe Lewalle. OncomiRs as noncoding RNAs having functions in cancer: Their role in immune suppression and clinical implications. Frontiers in Immunology 2022; 13 doi: 10.3389/fimmu.2022.913951
57
Radwa Ayman Salah, Shaimaa Shouman, Abd Elrahman Abouzid, Seif Ehab, Jihad El-Qassas, Alaa Mohamed, Nagwa El-Badri. Regenerative Medicine Applications in Chronic Diseases. Stem Cell Biology and Regenerative Medicine 2026; 80 doi: 10.1007/978-3-032-12705-1_11
58
Yi-Te Lee, Benjamin V. Tran, Jasmine J. Wang, Icy Y. Liang, Sungyong You, Yazhen Zhu, Vatche G. Agopian, Hsian-Rong Tseng, Ju Dong Yang. The Role of Extracellular Vesicles in Disease Progression and Detection of Hepatocellular Carcinoma. Cancers 2021; 13(12) doi: 10.3390/cancers13123076
59
Francisco A. Molina-Pelayo, David Zarate-Lopez, Rosendo García-Carrillo, César Rodríguez-Beas, Ramón Íñiguez-Palomares, José L. Rodríguez-Mejía, Adriana Soto-Guzmán, Gabriela Velasco-Loyden, Mónica Sierra-Martínez, Adolfo Virgen-Ortiz, Enrique Sánchez-Pastor, Nancy E. Magaña-Vergara, Rafael Baltiérrez-Hoyos, Javier Alamilla, Victoria Chagoya de Sánchez, Adán Dagnino-Acosta, Enrique Chávez, Luis Castro-Sánchez. miRNAs-Set of Plasmatic Extracellular Vesicles as Novel Biomarkers for Hepatocellular Carcinoma Diagnosis Across Tumor Stage and Etiologies. International Journal of Molecular Sciences 2025; 26(6) doi: 10.3390/ijms26062563
60
Rohit Ramesh Doke, Vrushali Bhalchim, Kuldeep Vinchurkar, Sudarshan Singh. Extracellular Vesicle-Based Biovectors for Diagnostic and Biomedical Applications. 2026;  doi: 10.1016/B978-0-443-36641-3.00019-X
61
Yi Gong, Xiaoyuan Wei, Wanwei Sun, Xin Ren, Jiao Chen, Jude Juventus Aweya, Hongyu Ma, Kok-Gan Chan, Yueling Zhang, Shengkang Li, Nuno Miguel Simões dos Santos. Exosomal miR-224 contributes to hemolymph microbiota homeostasis during bacterial infection in crustacean. PLOS Pathogens 2021; 17(8) doi: 10.1371/journal.ppat.1009837
62
Veronica Zelli, Chiara Compagnoni, Roberta Capelli, Alessandra Corrente, Mauro Di Vito Nolfi, Francesca Zazzeroni, Edoardo Alesse, Alessandra Tessitore. Role of exosomal microRNAs in cancer therapy and drug resistance mechanisms: focus on hepatocellular carcinoma. Frontiers in Oncology 2022; 12 doi: 10.3389/fonc.2022.940056
63
Jinbao Zhou, Hongshu Wang, Qiangling Sun, Xiaomin Liu, Zong Wu, Xianyi Wang, Wentao Fang, Zhongliang Ma. miR-224-5p-enriched exosomes promote tumorigenesis by directly targeting androgen receptor in non-small cell lung cancer. Molecular Therapy Nucleic Acids 2021; 23 doi: 10.1016/j.omtn.2021.01.028
64
Yudong Wu, Qian Li, Renshuai Zhang, Xiaoli Dai, Wujun Chen, Dongming Xing. Circulating microRNAs: Biomarkers of disease. Clinica Chimica Acta 2021; 516 doi: 10.1016/j.cca.2021.01.008
65
Zinnat Ara Moni, Zahid Hasan, Md. Shaheen Alam, Nitai Roy, Farhadul Islam. Diagnostic and Prognostic Significance of Exosomes and Their Components in Patients With Cancers. Cancer Medicine 2025; 14(1) doi: 10.1002/cam4.70569
66
Xiao-Cui Wei, Li-Juan Liu, Fan Zhu. Exosomes as potential diagnosis and treatment for liver cancer. World Journal of Gastrointestinal Oncology 2022; 14(1): 334-347 doi: 10.4251/wjgo.v14.i1.334
67
Khadijeh Mahboobnia, Dianne J. Beveridge, George C. Yeoh, Tasnuva D. Kabir, Peter J. Leedman. MicroRNAs in Hepatocellular Carcinoma Pathogenesis: Insights into Mechanisms and Therapeutic Opportunities. International Journal of Molecular Sciences 2024; 25(17) doi: 10.3390/ijms25179393
68
Lichao Yang, Chunmeng Wei, Yasi Li, Xiao He, Min He. Mir-224 Is An Early-Stage Biomarker of Hepatocellular Carcinoma with Mir-224 and Mir-125B As Prognostic Biomarkers. Biomarkers in Medicine 2020; 14(15) doi: 10.2217/bmm-2020-0099
69
Woo Ryung Kim, Eun Gyung Park, Yun Ju Lee, Woo Hyeon Bae, Du Hyeong Lee, Heui-Soo Kim. Integration of TE Induces Cancer Specific Alternative Splicing Events. International Journal of Molecular Sciences 2022; 23(18) doi: 10.3390/ijms231810918
70
Man Yao, Shufang Liang, Binbin Cheng. Role of exosomes in hepatocellular carcinoma and the regulation of traditional Chinese medicine. Frontiers in Pharmacology 2023; 14 doi: 10.3389/fphar.2023.1110922
71
Li Yu, Xiaonan Zeng, Xiao Hu, Qinglian Wen, Ping Chen. Advances and challenges in clinical applications of tumor cell-derived extracellular vesicles. Colloids and Surfaces B: Biointerfaces 2024; 234 doi: 10.1016/j.colsurfb.2023.113704
72
Eva Costanzi, Carolina Simioni, Gabriele Varano, Cinzia Brenna, Ilaria Conti, Luca Maria Neri. The Role of Extracellular Vesicles as Shuttles of RNA and Their Clinical Significance as Biomarkers in Hepatocellular Carcinoma. Genes 2021; 12(6) doi: 10.3390/genes12060902
73
Xiao-Na Liu, Dan-Ni Cui, Yu-Fang Li, Yun-He Liu, Gang Liu, Lei Liu. Multiple “Omics” data-based biomarker screening for hepatocellular carcinoma diagnosis. World Journal of Gastroenterology 2019; 25(29) doi: 10.3748/wjg.v25.i29.4199
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74
Mahda Delshad, Mohammad-Javad Sanaei, Mohammad Hossein Mohammadi, Amir Sadeghi, Davood Bashash. Exosomal Biomarkers: A Comprehensive Overview of Diagnostic and Prognostic Applications in Malignant and Non-Malignant Disorders. Biomolecules 2025; 15(4) doi: 10.3390/biom15040587
75
76
Wei Wang, Li-Ping Hao, Haizhu Song, Xiao-Yuan Chu, Rui Wang. The Potential Roles of Exosomal Non-Coding RNAs in Hepatocellular Carcinoma. Frontiers in Oncology 2022; 12 doi: 10.3389/fonc.2022.790916
77
Jacek Baj, Łukasz Bryliński, Filip Woliński, Michał Granat, Katarzyna Kostelecka, Piotr Duda, Jolanta Flieger, Grzegorz Teresiński, Grzegorz Buszewicz, Marzena Furtak-Niczyporuk, Piero Portincasa. Biomarkers and Genetic Markers of Hepatocellular Carcinoma and Cholangiocarcinoma—What Do We Already Know. Cancers 2022; 14(6) doi: 10.3390/cancers14061493
78
Elmira Gheytanchi, Fatemeh Tajik, Mahdieh Razmi, Sadegh Babashah, William Chi Shing Cho, Kiarash Tanha, Maryam Sahlolbei, Roya Ghods, Zahra Madjd. Circulating exosomal microRNAs as potential prognostic biomarkers in gastrointestinal cancers: a systematic review and meta-analysis. Cancer Cell International 2023; 23(1) doi: 10.1186/s12935-023-02851-8
79
Lanqian Su, Yuxin Yue, Yalan Yan, Jianming Sun, Lanxin Meng, Jiaan Lu, Lanyue Zhang, Jie Liu, Hao Chi, Sinian Liu, Zhongqiu Yang, Xiaowei Tang. Extracellular vesicles in hepatocellular carcinoma: unraveling immunological mechanisms for enhanced diagnosis and overcoming drug resistance. Frontiers in Immunology 2024; 15 doi: 10.3389/fimmu.2024.1485628
80
Raheleh Heydari, Meghdad Abdollahpour‐Alitappeh, Faezeh Shekari, Anna Meyfour. Emerging Role of Extracellular Vesicles in Biomarking the Gastrointestinal Diseases. Expert Review of Molecular Diagnostics 2021; 21(9) doi: 10.1080/14737159.2021.1954909
81
Carlos González-Blanco, Sarai Iglesias-Fortes, Ángela Cristina Lockwood, César Figaredo, Daniela Vitulli, Carlos Guillén. The Role of Extracellular Vesicles in Metabolic Diseases. Biomedicines 2024; 12(5) doi: 10.3390/biomedicines12050992
82
Ting Song, Li Li, Shaobo Wu, Yan Liu, Caiping Guo, Wen Wang, Lili Dai, Tong Zhang, Hao Wu, Bin Su. Peripheral Blood Genetic Biomarkers for the Early Diagnosis of Hepatocellular Carcinoma. Frontiers in Oncology 2021; 11 doi: 10.3389/fonc.2021.583714
83
Yangyang Zhou, Hezhen Liu, Hongxia Chen. Advancement in exosome isolation and label-free detection towards clinical diagnosis. TrAC Trends in Analytical Chemistry 2024; 179 doi: 10.1016/j.trac.2024.117874
84
Expert consensus on the role of hematological markers in the early clinical screening of hepatocellular carcinoma. Liver Research 2022; 6(2) doi: 10.1016/j.livres.2022.04.001
85
Atsunori Tsuchiya, Kazuki Natsui, Yui Ishii, Yohei Koseki, Nobutaka Takeda, Kei Tomiyoshi, Fusako Yamazaki, Yuki Yoshida, Shuji Terai. Small extracellular vesicles and liver diseases: From diagnosis to therapy. World Journal of Hepatology 2022; 14(7): 1307-1318 doi: 10.4254/wjh.v14.i7.1307
86
Suman Kumari, Christopher Lausted, Kelsey Scherler, Alphonsus H. C. Ng, Yue Lu, Inyoul Lee, Leroy Hood, Kai Wang. Approaches and Challenges in Characterizing the Molecular Content of Extracellular Vesicles for Biomarker Discovery. Biomolecules 2024; 14(12) doi: 10.3390/biom14121599
87
Xiao-Na Liu, Dan-Ni Cui, Yu-Fang Li, Yun-He Liu, Gang Liu, Lei Liu. Multiple “Omics” data-based biomarker screening for hepatocellular carcinoma diagnosis. World Journal of Gastroenterology 2019; 25(30): 4199-4212 doi: 10.3748/wjg.v25.i30.4199
88
Karmele Valencia, Luis M. Montuenga. Exosomes in Liquid Biopsy: The Nanometric World in the Pursuit of Precision Oncology. Cancers 2021; 13(9) doi: 10.3390/cancers13092147
89
Andrei Sorop, Diana Constantinescu, Florentina Cojocaru, Anca Dinischiotu, Dana Cucu, Simona Olimpia Dima. Exosomal microRNAs as Biomarkers and Therapeutic Targets for Hepatocellular Carcinoma. International Journal of Molecular Sciences 2021; 22(9) doi: 10.3390/ijms22094997
90
A-Reum Kim, Minseok Kang, Dong-Young Kim, Kidus Haile Yemaneberhan, Dongho Choi. Extracellular Vesicles in Liver Disease: Redefining Diagnostic and Therapeutic Strategies. International Journal of Stem Cells 2026; 19(1) doi: 10.15283/ijsc25052