| For: | Lin D, Wu J. Hypoxia inducible factor in hepatocellular carcinoma: A therapeutic target. World J Gastroenterol 2015; 21(42): 12171-12178 [PMID: 26576101 DOI: 10.3748/wjg.v21.i42.12171] |
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| URL: | https://www.wjgnet.com/1007-9327/full/v21/i42/12171.htm |
| Number | Citing Articles |
| 1 |
Stavros P. Papadakos, Ioanna E. Stergiou, Nikolina Gkolemi, Konstantinos Arvanitakis, Stamatios Theocharis. Unraveling the Significance of EPH/Ephrin Signaling in Liver Cancer: Insights into Tumor Progression and Therapeutic Implications. Cancers 2023; 15(13) doi: 10.3390/cancers15133434
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| 2 |
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| 3 |
Weiwei Hu, Shufang Zheng, Haixin Guo, Beiying Dai, Jiaping Ni, Yaohong Shi, Hanrui Bian, Lanxin Li, Yumeng Shen, Mo Wu, Zhoutong Tian, Guilai Liu, Md Amir Hossain, Hongbao Yang, Duowei Wang, Qin Zhang, Jun Yu, Lutz Birnbaumer, Jifeng Feng, Decai Yu, Yong Yang. PLAGL2‐EGFR‐HIF‐1/2α Signaling Loop Promotes HCC Progression and Erlotinib Insensitivity. Hepatology 2021; 73(2) doi: 10.1002/hep.31293
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| 4 |
Takayuki Shimizu, Taku Aoki, Shozo Mori, Yukihiro Iso, Masato Kato, Mitsuru Ishizuka, Keiichi Kubota. Tumor DNA-dependent protein kinase catalytic subunit expression is associated with hepatitis B surface antigen status and tumor progression in patients with hepatocellular carcinoma. Scientific Reports 2018; 8(1) doi: 10.1038/s41598-018-33427-6
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| 5 |
Carolina Méndez-Blanco, Flavia Fondevila, Andrés García-Palomo, Javier González-Gallego, José L. Mauriz. Sorafenib resistance in hepatocarcinoma: role of hypoxia-inducible factors. Experimental & Molecular Medicine 2018; 50(10) doi: 10.1038/s12276-018-0159-1
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| 6 |
Weiguo Hong, Yan Hu, Zhenping Fan, Rong Gao, Ruichuang Yang, Jingfeng Bi, Jun Hou. In silico identification of EP400 and TIA1 as critical transcription factors involved in human hepatocellular carcinoma relapse. Oncology Letters 2019; doi: 10.3892/ol.2019.11171
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| 7 |
Zhiqiang Chen, Xueliang Zuo, Yao Zhang, Guoyong Han, Long Zhang, Jindao Wu, Xuehao Wang. MiR-3662 suppresses hepatocellular carcinoma growth through inhibition of HIF-1α-mediated Warburg effect. Cell Death & Disease 2018; 9(5) doi: 10.1038/s41419-018-0616-8
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| 8 |
Hui-xing Zhang, You Kang, Ning Li, Hai-feng Wang, Yong-rui Bao, Yan-wu Li, Xue-zheng Li, Zhe Jiang, Gang Chen. Triterpenoids from Liquidambar Fructus induced cell apoptosis via a PI3K-AKT related signal pathway in SMMC7721 cancer cells. Phytochemistry 2020; 171 doi: 10.1016/j.phytochem.2019.112228
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| 9 |
. 2019; doi: 10.70675/13a32e69z1eb7z4416za3b9z5e1e77176186
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| 10 |
Liangfang Yao, Yang Xuan, Haiyang Zhang, Bo Yang, Xinglong Ma, Tianzhen Wang, Tianyuan Meng, Wenshe Sun, Haibin Wei, Xueqing Ma, Robb Moses, Jianru Xiao, Pei Zhang, Chao Ge, Jinjun Li, Lei Li, Xiaotao Li, Jinbao Li, Bianhong Zhang. Reciprocal REGγ-mTORC1 regulation promotes glycolytic metabolism in hepatocellular carcinoma. Oncogene 2021; 40(3) doi: 10.1038/s41388-020-01558-8
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| 11 |
Eloi R Verrier, Amélie Weiss, Charlotte Bach, Laura Heydmann, Vincent Turon-Lagot, Arnaud Kopp, Houssein El Saghire, Emilie Crouchet, Patrick Pessaux, Thomas Garcia, Patrick Pale, Mirjam B Zeisel, Camille Sureau, Catherine Schuster, Laurent Brino, Thomas F Baumert. Combined small molecule and loss-of-function screen uncovers estrogen receptor alpha and CAD as host factors for HDV infection and antiviral targets. Gut 2020; 69(1) doi: 10.1136/gutjnl-2018-317065
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| 12 |
Kurt Sartorius, Samuel O. Antwi, Anil Chuturgoon, Lewis R. Roberts, Anna Kramvis. RNA Therapeutic Options to Manage Aberrant Signaling Pathways in Hepatocellular Carcinoma: Dream or Reality?. Frontiers in Oncology 2022; 12 doi: 10.3389/fonc.2022.891812
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| 13 |
Bin Zhu, Shaoying Pan, Juanjuan Liu, Suli Wang, Ying Ni, Linlin Xiao, Quhao Wei, You Peng, Zhiyong Ding, Wenli Zhao. HIF‐1α forms regulatory loop with YAP to coordinate hypoxia‐induced adriamycin resistance in acute myeloid leukemia cells. Cell Biology International 2020; 44(2) doi: 10.1002/cbin.11246
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| 14 |
Zhan-Jun Ma, Xue-Xi Wang, Gang Su, Jing-Jing Yang, Ya-Juan Zhu, You-Wei Wu, Jing Li, Li Lu, Long Zeng, Hai-Xia Pei. Proteomic analysis of apoptosis induction by lariciresinol in human HepG2 cells. Chemico-Biological Interactions 2016; 256 doi: 10.1016/j.cbi.2016.07.011
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| 15 |
Xiaomeng Dai, Guoliang Pi, Sheng-li Yang, George G. Chen, Li-ping Liu, Han-Hua Dong. Association of PD-L1 and HIF-1α Coexpression with Poor Prognosis in Hepatocellular Carcinoma. Translational Oncology 2018; 11(2) doi: 10.1016/j.tranon.2018.02.014
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| 16 |
Hai Jin, Qian Liu, Jin Li, Siyu Zhao, Biguang Tuo. Multifaceted roles of lactate dehydrogenase in liver cancer (Review). International Journal of Oncology 2025; 66(6) doi: 10.3892/ijo.2025.5756
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| 17 |
Fei Jia, Baolin Wu, Ruifang Yan, Lei Li, Kaiyu Wang, Dongming Han. Prediction Model for Intermediate‐Stage Hepatocellular Carcinoma Response to Transarterial Chemoembolization. Journal of Magnetic Resonance Imaging 2020; 52(6) doi: 10.1002/jmri.27189
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| 18 |
Sha Fu, Rong-rong Zhou, Ning Li, Yan Huang, Xue-Gong Fan. Hepatitis B virus X protein in liver tumor microenvironment. Tumor Biology 2016; 37(12) doi: 10.1007/s13277-016-5406-2
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| 19 |
Yongdong Liu, Liling Sun, Xingwang Su, Sien Guo. Inhibition of eukaryotic initiation factor 4E phosphorylation by cercosporamide selectively suppresses angiogenesis, growth and survival of human hepatocellular carcinoma. Biomedicine & Pharmacotherapy 2016; 84 doi: 10.1016/j.biopha.2016.09.038
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| 20 |
Zahra Farzaneh, Massoud Vosough, Tarun Agarwal, Maryam Farzaneh. Critical signaling pathways governing hepatocellular carcinoma behavior; small molecule-based approaches. Cancer Cell International 2021; 21(1) doi: 10.1186/s12935-021-01924-w
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| 21 |
Shaohui He, Haifeng Wei, Yifei Ma, Jian Zhao, Wei Xu, Jianru Xiao. Outcomes of metastatic spinal cord compression secondary to primary hepatocellular carcinoma with multidisciplinary treatments. Oncotarget 2017; 8(26) doi: 10.18632/oncotarget.15708
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| 22 |
Sheng‑Li Yang, Cui Zeng, Xiefan Fang, Qian‑Jin He, Li‑Ping Liu, Shi‑Yun Bao, Xiaoli Pan, Zhi‑Fan Xiong. Hepatitis B virus upregulates GP73 expression by activating the HIF-2α signaling pathway. Oncology Letters 2018; doi: 10.3892/ol.2018.7955
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| 23 |
Shuaijun Ma, Yafan Chen, Penghe Quan, Jingliang Zhang, Shichao Han, Guohui Wang, Ruochen Qi, Xiaoyan Zhang, Fuli Wang, Jianlin Yuan, Xiaojian Yang, Weijing Jia, Weijun Qin. NPAS2 promotes aerobic glycolysis and tumor growth in prostate cancer through HIF-1A signaling. BMC Cancer 2023; 23(1) doi: 10.1186/s12885-023-10685-w
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| 24 |
Néstor Prieto-Domínguez, Carolina Méndez-Blanco, Sara Carbajo-Pescador, Flavia Fondevila, Andrés García-Palomo, Javier González-Gallego, José L. Mauriz. Melatonin enhances sorafenib actions in human hepatocarcinoma cells by inhibiting mTORC1/p70S6K/HIF-1α and hypoxia-mediated mitophagy. Oncotarget 2017; 8(53) doi: 10.18632/oncotarget.20592
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| 25 |
Aldona Kasprzak, Agnieszka Adamek. Role of Endoglin (CD105) in the Progression of Hepatocellular Carcinoma and Anti-Angiogenic Therapy. International Journal of Molecular Sciences 2018; 19(12) doi: 10.3390/ijms19123887
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| 26 |
Saimila Momin, Ganji Purnachandra Nagaraju. Novel therapeutic approaches for gastrointestinal malignancies. Diagnostics and Therapeutic Advances in GI Malignancies 2020; doi: 10.1007/978-981-15-5471-1_15
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| 27 |
Fan Pan, Xin-Rong Lin, Li-Ping Hao, Xiao-Yuan Chu, Hai-Jun Wan, Rui Wang. The Role of RNA Methyltransferase METTL3 in Hepatocellular Carcinoma: Results and Perspectives. Frontiers in Cell and Developmental Biology 2021; 9 doi: 10.3389/fcell.2021.674919
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| 28 |
Wenyue Gao, Jing Wang, Yuting Xu, Hongbo Yu, Sitong Yi, Changchuan Bai, Qingwei Cong, Ying Zhu. Research progress in the metabolic reprogramming of hepatocellular carcinoma (Review). Molecular Medicine Reports 2024; 30(1) doi: 10.3892/mmr.2024.13255
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| 29 |
Rona Harari-Steinfeld, Maytal Gefen, Alina Simerzin, Elina Zorde-Khvalevsky, Mila Rivkin, Ezra Ella, Tomer Friehmann, Mordechay Gerlic, Jessica Zucman-Rossi, Stefano Caruso, Mélissa Leveille, Jennifer L. Estall, Daniel S. Goldenberg, Hilla Giladi, Eithan Galun, Zohar Bromberg. The lncRNA H19-Derived MicroRNA-675 Promotes Liver Necroptosis by Targeting FADD. Cancers 2021; 13(3) doi: 10.3390/cancers13030411
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| 30 |
Simona Del Giudice, Valentina De Luca, Seyedehnegar Parizadeh, Domenico Russo, Alberto Luini, Rosaria Di Martino. Endogenous and Exogenous Regulatory Signaling in the Secretory Pathway: Role of Golgi Signaling Molecules in Cancer. Frontiers in Cell and Developmental Biology 2022; 10 doi: 10.3389/fcell.2022.833663
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| 31 |
Bao-Hua Li, Malgorzata A. Garstka, Zong-Fang Li. Chemokines and their receptors promoting the recruitment of myeloid-derived suppressor cells into the tumor. Molecular Immunology 2020; 117 doi: 10.1016/j.molimm.2019.11.014
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| 32 |
Pengkai Ma, Jianhua Chen, Haixian Qu, Ye Li, Xiaohui Li, Xuemei Tang, Zhigang Song, Hainan Xin, Jinbang Zhang, Jingxue Nai, Zhiping Li, Zhijun Wang. Hypoxic targeting and activating TH-302 loaded transcatheter arterial embolization microsphere. Drug Delivery 2020; 27(1) doi: 10.1080/10717544.2020.1831102
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| 33 |
Qiangnu Zhang, Qian Cheng, Mengting Xia, Xiaotao Huang, Xiaoyan He, Juan Liao. Hypoxia-Induced lncRNA-NEAT1 Sustains the Growth of Hepatocellular Carcinoma via Regulation of miR-199a-3p/UCK2. Frontiers in Oncology 2020; 10 doi: 10.3389/fonc.2020.00998
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| 34 |
Kunyuan Wang, Chenxi Duan, Xuejing Zou, Yang Song, Wenwen Li, Lushan Xiao, Jie Peng, Liheng Yao, Qian Long, Li Liu. Increased mediator complex subunit 15 expression is associated with poor prognosis in hepatocellular carcinoma. Oncology Letters 2018; doi: 10.3892/ol.2018.7820
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| 35 |
Qiangnu Zhang, Lijun Qiao, Quan Liu, Xiangpan Kong, Jun Hu, Weibin Hu, Zongze Wu, Mingyue Li, Liping Liu. Hypoxia associated multi-omics molecular landscape of tumor tissue in patients with hepatocellular carcinoma. Aging 2021; 13(5) doi: 10.18632/aging.202723
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| 36 |
Honglin Yan, Na He, Shuixiang He. HCG15 is a hypoxia-responsive lncRNA and facilitates hepatocellular carcinoma cell proliferation and invasion by enhancing ZNF641 transcription. Biochemical and Biophysical Research Communications 2022; 608 doi: 10.1016/j.bbrc.2022.03.143
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| 37 |
Min Li, Yujie Su, Fangrong Zhang, Kerong Chen, Xiangting Xu, Lin Xu, Jianping Zhou, Wei Wang. A dual-targeting reconstituted high density lipoprotein leveraging the synergy of sorafenib and antimiRNA21 for enhanced hepatocellular carcinoma therapy. Acta Biomaterialia 2018; 75 doi: 10.1016/j.actbio.2018.05.049
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| 38 |
Sheng-Li Yang, Quan-Guang Ren, Tao Zhang, Xiaoli Pan, Lu Wen, Jian-Li Hu, Chao Yu, Qian-Jin He. Hepatitis B virus X protein and hypoxia-inducible factor-1α stimulate Notch gene expression in liver cancer cells. Oncology Reports 2017; 37(1) doi: 10.3892/or.2016.5211
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| 39 |
Wen-Sheng Tzeng, Wei-Lin Teng, Pao-Hsien Huang, Tzu-Ching Lin, Feng-Lin Yen, Yow-Ling Shiue. Pterostilbene Nanoparticles Downregulate Hypoxia-Inducible Factors in Hepatoma Cells Under Hypoxic Conditions. International Journal of Nanomedicine 2021; doi: 10.2147/IJN.S282172
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| 40 |
Rajesh P. Shah, Paul F. Laeseke, Lewis K. Shin, Frederick T. Chin, Nishita Kothary, George M. Segall. Limitations of Fluorine 18 Fluoromisonidazole in Assessing Treatment-induced Tissue Hypoxia after Transcatheter Arterial Embolization of Hepatocellular Carcinoma: A Prospective Pilot Study. Radiology: Imaging Cancer 2022; 4(3) doi: 10.1148/rycan.210094
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| 41 |
Wafaa Abumustafa, Darko Castven, Fatemeh Saheb Sharif-Askari, Batoul Abi Zamer, Mawieh Hamad, Jens-Uwe Marquardt, Jibran Sualeh Muhammad. PRMT5 Mediated HIF1α Signaling and Ras-Related Nuclear Protein as Promising Biomarker in Hepatocellular Carcinoma. Biology 2024; 13(4) doi: 10.3390/biology13040216
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| 42 |
Xiu Lv, Jincheng Li, Chuhong Zhang, Tian Hu, Sai Li, Sha He, Hanxing Yan, Yixi Tan, Mingsheng Lei, Meiling Wen, Jianhong Zuo. The role of hypoxia-inducible factors in tumor angiogenesis and cell metabolism. Genes & Diseases 2017; 4(1) doi: 10.1016/j.gendis.2016.11.003
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| 43 |
Huirong Xu, Yeqiang Chen, Zhongchao Li, Hao Zhang, Jingzhou Liu, Jianjun Han. The hypoxia-inducible factor 1 inhibitor LW6 mediates the HIF-1α/PD-L1 axis and suppresses tumor growth of hepatocellular carcinoma in vitro and in vivo. European Journal of Pharmacology 2022; 930 doi: 10.1016/j.ejphar.2022.175154
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| 44 |
Hong Wu, Tao Wang, Yiqiang Liu, Xin Li, Senlin Xu, Changtao Wu, Hongbo Zou, Mianfu Cao, Guoxiang Jin, Jinyi Lang, Bin Wang, Baohua Liu, Xiaolin Luo, Chuan Xu. Mitophagy promotes sorafenib resistance through hypoxia-inducible ATAD3A dependent Axis. Journal of Experimental & Clinical Cancer Research 2020; 39(1) doi: 10.1186/s13046-020-01768-8
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| 45 |
Inga Hochnadel, Lisa Hoenicke, Nataliia Petriv, Huizhen Suo, Lothar Groebe, Chantal Olijnik, Nina Bondarenko, Juan C. Alfonso, Michael Jarek, Ruibing Shi, Andreas Jeron, Kai Timrott, Tatjana Hirsch, Nils Jedicke, Dunja Bruder, Frank Klawonn, Ralf Lichtinghagen, Robert Geffers, Henrike Lenzen, Michael P. Manns, Tetyana Yevsa. In vivo RNAi screen and validation reveals Ngp, Hba-a1, and S100a8 as novel inhibitory targets on T lymphocytes in liver cancer. Frontiers in Immunology 2025; 16 doi: 10.3389/fimmu.2025.1549229
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| 46 |
Jiawei Du, Yong Shao, Zhiwei Zhang, Xiaozheng Wei, Shiyi Pan, Ying Hu, Meng yan Zhai, Qian Dai, Wei Cao, Jiong Gu. Biomimetic cell membrane-fused liposomes for co-delivery of sorafenib and oxygen potentiate therapy against hypoxic hepatocellular carcinoma. Journal of Drug Delivery Science and Technology 2026; 116 doi: 10.1016/j.jddst.2025.107855
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| 47 |
Yijun Mei, Lu Tang, Qiaqia Xiao, Ziqi Zhang, Ziyao Zhang, Jing Zang, Jianping Zhou, Ying Wang, Wei Wang, Min Ren. Reconstituted high density lipoprotein (rHDL), a versatile drug delivery nanoplatform for tumor targeted therapy. Journal of Materials Chemistry B 2021; 9(3) doi: 10.1039/D0TB02139C
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| 48 |
Jelena Djokic Kovac, Tamara Milovanovic, Vladimir Dugalic, Igor Dumic. Pearls and pitfalls in magnetic resonance imaging of hepatocellular carcinoma. World Journal of Gastroenterology 2020; 26(17): 2012-2029 doi: 10.3748/wjg.v26.i17.2012
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| 49 |
Lijun Qiao, Weibin Hu, Linzhi Li, Xin Chen, Liping Liu, Jingbo Wang. USP11 promotes glycolysis by regulating HIF‐1α stability in hepatocellular carcinoma. Journal of Cellular and Molecular Medicine 2024; 28(2) doi: 10.1111/jcmm.18017
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| 50 |
Zhe Li, Jinshuai Lan, Ya Wu, Lixia Chen, Donghao Gu, Liyan Sun, Siqi Yang, Yi Shen, Tong Zhang, Yue Ding. Sensitizing sorafenib to hepatocellular carcinoma with dual-targeted and pH-responsive nanodrugs via overcoming the hypoxia tumor microenvironment. Chemical Engineering Journal 2024; 500 doi: 10.1016/j.cej.2024.157231
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| 51 |
Yihui Ma, Wenwen Sun, Qiangnu Zhang, Bingfang Gao, Wen Cai, QinLiang Liu, Juan Liao, Xinli Wang. lncRNA BSG-AS1 is hypoxia-responsive and promotes hepatocellular carcinoma by enhancing BSG mRNA stability. Biochemical and Biophysical Research Communications 2021; 566 doi: 10.1016/j.bbrc.2021.06.002
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| 52 |
Frank Jühling, Antonio Saviano, Clara Ponsolles, Laura Heydmann, Emilie Crouchet, Sarah C Durand, Houssein El Saghire, Emanuele Felli, Véronique Lindner, Patrick Pessaux, Nathalie Pochet, Catherine Schuster, Eloi R Verrier, Thomas F Baumert. Hepatitis B virus compartmentalization and single-cell differentiation in hepatocellular carcinoma. Life Science Alliance 2021; 4(9) doi: 10.26508/lsa.202101036
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| 53 |
Fei Huang, Junying Chen, Ruilong Lan, Zeng Wang, Ruiqing Chen, Jingan Lin, Lengxi Fu. Hypoxia induced δ-Catenin to enhance mice hepatocellular carcinoma progression via Wnt signaling. Experimental Cell Research 2019; 374(1) doi: 10.1016/j.yexcr.2018.11.011
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| 54 |
Takashi Himoto, Tsutomu Masaki. Current Trends on the Involvement of Zinc, Copper, and Selenium in the Process of Hepatocarcinogenesis. Nutrients 2024; 16(4) doi: 10.3390/nu16040472
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| 55 |
Sandeep Arora, Roberta Catania, Amir Borhani, Natally Horvat, Kathryn Fowler, Carla Harmath. HCC: role of pre- and post-treatment tumor biology in driving adverse outcomes and rare responses to therapy. Abdominal Radiology 2021; 46(8) doi: 10.1007/s00261-021-03192-8
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| 56 |
Xiaomeng Dai, Jian Ruan, Yixuan Guo, Zhu Sun, Junqing Liu, Xuanwen Bao, Hangyu Zhang, Qiong Li, Chanqi Ye, Xun Wang, Chun-Xia Zhao, Feng Zhou, Jianpeng Sheng, Dong Chen, Peng Zhao. Enhanced radiotherapy efficacy and induced anti-tumor immunity in HCC by improving hypoxia microenvironment using oxygen microcapsules. Chemical Engineering Journal 2021; 422 doi: 10.1016/j.cej.2021.130109
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| 57 |
Cynthia Ju, Sean P. Colgan, Holger K. Eltzschig. Hypoxia-inducible factors as molecular targets for liver diseases. Journal of Molecular Medicine 2016; 94(6) doi: 10.1007/s00109-016-1408-1
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| 58 |
Zeli Tang, Caibiao Wei, Xueling Deng, Qiumei Lin, Qiping Hu, Shitao Li, Jilong Wang, Yuhong Wu, Dengyu Liu, Min Fang, Tingzheng Zhan. Serum proteomic and metabolomic profiling of hepatocellular carcinoma patients co-infected with Clonorchis sinensis. Frontiers in Immunology 2025; 15 doi: 10.3389/fimmu.2024.1489077
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| 59 |
Tian-yi Zhou, Lin-han Zhuang, Yan Hu, Yu-lu Zhou, Wen-kai Lin, Dan-dan Wang, Zi-qian Wan, Lin-lin Chang, Ying Chen, Mei-dan Ying, Zi-bo Chen, Song Ye, Jian-shu Lou, Qiao-jun He, Hong Zhu, Bo Yang. Inactivation of hypoxia-induced YAP by statins overcomes hypoxic resistance tosorafenib in hepatocellular carcinoma cells. Scientific Reports 2016; 6(1) doi: 10.1038/srep30483
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| 60 |
Fei Huang, Junying Chen, Ruilong Lan, Zeng Wang, Ruiqing Chen, Jingan Lin, Lurong Zhang, Lengxi Fu. δ-Catenin peptide vaccines repress hepatocellular carcinoma growth via CD8+ T cell activation. OncoImmunology 2018; doi: 10.1080/2162402X.2018.1450713
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| 61 |
Mi Kyoung Song, Gi Beom Kim, Eun Jung Bae, Young Ah Lee, Hyun-Young Kim, Seung-Kee Min, Jung Hee Kim, Jae-Kyung Won. Pheochromocytoma and paraganglioma in Fontan patients: Common more than expected. Congenital Heart Disease 2018; 13(4) doi: 10.1111/chd.12625
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| 62 |
Mirella Pastore, Giulia Lori, Alessandra Gentilini, Maria Letizia Taddei, Giovanni Di Maira, Claudia Campani, Stefania Recalcati, Pietro Invernizzi, Fabio Marra, Chiara Raggi. Multifaceted Aspects of Metabolic Plasticity in Human Cholangiocarcinoma: An Overview of Current Perspectives. Cells 2020; 9(3) doi: 10.3390/cells9030596
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| 63 |
Huamei Wei, Zuoming Xu, Liucui Chen, Qing Wei, Zihua Huang, Guoman Liu, Wenchuan Li, Jianchu Wang, Qianli Tang, Jian Pu. Long non-coding RNA PAARH promotes hepatocellular carcinoma progression and angiogenesis via upregulating HOTTIP and activating HIF-1α/VEGF signaling. Cell Death & Disease 2022; 13(2) doi: 10.1038/s41419-022-04505-5
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| 64 |
Jian Yan, Yi‐Xuan Deng, Yu‐Lian Cai, Wen‐Dong Cong. LncRNA MIR17HG promotes the proliferation, migration, and invasion of retinoblastoma cells by up‐regulating HIF‐1α expression via sponging miR‐155‐5p. The Kaohsiung Journal of Medical Sciences 2022; 38(6) doi: 10.1002/kjm2.12523
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| 65 |
Han Chen, Jiayi Wan, Siwen Lv, Chuanxiang Yao, Ye Tong, Xiutian Peng, Huiwen Wang, Siyuan Hou, Biqing Wu, Yinping Jin, Jiazhe Song, Kai Xue. Ginsenoside Rg2 inhibits the cell viability of cisplatin-resistant epithelial ovarian cancer by suppressing CACNA1G-mediated calcium signaling. Toxicology and Applied Pharmacology 2026; 516 doi: 10.1016/j.taap.2026.118031
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| 66 |
Wanyuan Ruan, Yushi Yang, Qionghua Yu, Tiejun Huang, Yaofen Wang, Li Hua, Zhirui Zeng, Runsang Pan. FUT11 is a target gene of HIF1α that promotes the progression of hepatocellular carcinoma. Cell Biology International 2021; 45(11) doi: 10.1002/cbin.11675
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| 67 |
Hui‐Hui Zhang, Ying Zhang, Yan‐Na Cheng, Fu‐Lian Gong, Zhan‐Qi Cao, Lu‐Gang Yu, Xiu‐Li Guo. Metformin incombination with curcumin inhibits the growth, metastasis, and angiogenesis of hepatocellular carcinoma in vitro and in vivo. Molecular Carcinogenesis 2018; 57(1) doi: 10.1002/mc.22718
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| 68 |
Imanol Zubiete-Franco, Juan L. García-Rodríguez, Fernando Lopitz-Otsoa, Marina Serrano-Macia, Jorge Simon, Pablo Fernández-Tussy, Lucía Barbier-Torres, David Fernández-Ramos, Virginia Gutiérrez-de-Juan, Sergio López de Davalillo, Onintza Carlevaris, Adolfo Beguiristain Gómez, Erica Villa, Diego Calvisi, César Martín, Edurne Berra, Patricia Aspichueta, Naiara Beraza, Marta Varela-Rey, Matias Ávila, Manuel S. Rodríguez, José M. Mato, Irene Díaz-Moreno, Antonio Díaz-Quintana, Teresa C. Delgado, María L. Martínez-Chantar. SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer. EBioMedicine 2019; 40 doi: 10.1016/j.ebiom.2018.12.031
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| 69 |
Dashuai Yang, Fangrui Zhao, Yu Zhou, Yanbing Zhang, Jie Shen, Bin Yu, Kailiang Zhao, Youming Ding. S100A16 is a potential target for reshaping the tumor microenvironment in the hypoxic context of liver cancer. International Immunopharmacology 2024; 134 doi: 10.1016/j.intimp.2024.112076
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| 70 |
Xuejing Wang, Ling Yin, Mengyin Chai, Buxin Kou, Xiaoni Liu, Xiaojun Wang. Hu-Qi-Zheng-Xiao Decoction Inhibits the Metastasis of Hepatocellular Carcinoma Cells by Suppressing the HIF-1α Signaling Pathway to Inhibit EMT, LCSC, and Angiogenic Process. Integrative Cancer Therapies 2024; 23 doi: 10.1177/15347354231226126
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| 71 |
Early Recurrence of HCC Is Driven by Inflammation-Related HIF-1α Independent Angiogenesis Rather than Hypoxia-Induced Immune Escape. Biomolecules 2026; 16(5) doi: 10.3390/biom16050723
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| 72 |
Rui Huang, Lijun Zhang, Jinmei Jin, Yudong Zhou, Hongwei Zhang, Chao Lv, Dong Lu, Ye Wu, Hong Zhang, Sanhong Liu, Hongzhuan Chen, Xin Luan, Weidong Zhang. Bruceine D inhibits HIF-1α-mediated glucose metabolism in hepatocellular carcinoma by blocking ICAT/β-catenin interaction. Acta Pharmaceutica Sinica B 2021; 11(11) doi: 10.1016/j.apsb.2021.05.009
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| 73 |
Khaled Mahmoud, Mahmoud Teaima, Yasmeen Attia, Jingjing Sun, Mohamed El-Nabarawi, Shady Swidan. Reprogramming hepatocellular carcinoma: Nanomedicine at the crossroads of molecular targets and smart delivery. Colloids and Surfaces B: Biointerfaces 2026; 268 doi: 10.1016/j.colsurfb.2026.115981
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| 74 |
Hae Seong Song, Young Ho Song, Nem Singh, Hyunuk Kim, Hyelin Jeon, Inhye Kim, Se Chan Kang, Ki-Whan Chi. New Self-assembled Supramolecular Bowls as Potent Anticancer Agents for Human Hepatocellular Carcinoma. Scientific Reports 2019; 9(1) doi: 10.1038/s41598-018-36755-9
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| 75 |
Siti A Sulaiman, Nadiah Abu, Nurul-Syakima Ab-Mutalib, Teck Yew Low, Rahman Jamal. Signatures of Gene Expression, DNA Methylation and microRNAs of Hepatocellular Carcinoma with Vascular Invasion. Future Oncology 2019; 15(22) doi: 10.2217/fon-2018-0909
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| 76 |
Xuhua Duan, Wenze Xu, Hao Li, Manzhou Wang, Wenhui Wang, Huibin Lu, Yancang Zhang, Xinwei Han. Nrf2-siRNA Enhanced the Anti-Tumor Effects of As2O3 in 5-Fluorouracil-Resistant Hepatocellular Carcinoma by Inhibiting HIF-1α/HSP70 Signaling. Journal of Hepatocellular Carcinoma 2022; doi: 10.2147/JHC.S388077
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| 77 |
Haohao Lu, Bin Liang, Chuansheng Zheng, Yanyan Cao, Xiangwen Xia. Efficacy and safety analysis of TACE combined with lenvatinib and icaritin in unresectable hepatocellular carcinoma with poor performance status. BMC Cancer 2026; 26(1) doi: 10.1186/s12885-026-16322-6
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| 78 |
Chunyu Zhao, Shanshuo Liu, Feng Gao, Yawen Zou, Zhigang Ren, Zujiang Yu. The role of tumor microenvironment reprogramming in primary liver cancer chemotherapy resistance. Frontiers in Oncology 2022; 12 doi: 10.3389/fonc.2022.1008902
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| 79 |
Suryaa Manoharan, Viswaganesh Venkatesan, Ekambaram Perumal. An integrative genomic analysis of angiogenesis in hepatocellular carcinoma: from canonical drivers to emerging biomarkers. Naunyn-Schmiedeberg's Archives of Pharmacology 2026; 399(7) doi: 10.1007/s00210-026-05052-y
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