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For: Jaganathan SK, Vellayappan MV, Narasimhan G, Supriyanto E, Octorina Dewi DE, Narayanan ALT, Balaji A, Subramanian AP, Yusof M. Chemopreventive effect of apple and berry fruits against colon cancer. World J Gastroenterol 2014; 20(45): 17029-17036 [PMID: 25493015 DOI: 10.3748/wjg.v20.i45.17029]
URL: https://www.wjgnet.com/1007-9327/full/v20/i45/17029.htm
Number Citing Articles
1
Pegah Rafiee, Nitin Shivappa, James R. Hébert, Saeede Jaafari Nasab, Alireza Bahrami, Azita Hekmatdoost, Bahram Rashidkhani, Amir Sadeghi, Mohammad Houshyari, Ehsan Hejazi. Dietary Inflammatory Index and Odds of Colorectal Cancer and Colorectal Adenomatous Polyps in a Case-Control Study from Iran. Nutrients 2019; 11(6) doi: 10.3390/nu11061213
2
Teng-Fei Yin, Min Wang, Ying Qing, Ying-Min Lin, Dong Wu. Research progress on chemopreventive effects of phytochemicals on colorectal cancer and their mechanisms. World Journal of Gastroenterology 2016; 22(31): 7058-7068 doi: 10.3748/wjg.v22.i31.7058
3
Mo Zhu, Ting Xu, Lindong Ji, Baofei Jiang, Kun Wu. MIR143HG promotes methylation of transcription factor HOXB7 promoter by recruiting methyltransferase DNMT1 to prevent the progression of colon cancer. The FASEB Journal 2024; 38(1) doi: 10.1096/fj.202301060RRR
4
Shalika Rana, Shiv Kumar, Ajay Rana, Yogendra Padwad, Shashi Bhushan. Biological activity of phenolics enriched extracts from industrial apple pomace. Industrial Crops and Products 2021; 160 doi: 10.1016/j.indcrop.2020.113158
5
Miljana Nenkov, Yunxia Ma, Nikolaus Gaßler, Yuan Chen. Metabolic Reprogramming of Colorectal Cancer Cells and the Microenvironment: Implication for Therapy. International Journal of Molecular Sciences 2021; 22(12) doi: 10.3390/ijms22126262
6
Bee Ling Tan, Mohd Esa Norhaizan. The Role of Antioxidants in Longevity and Age-Related Diseases. 2021;  doi: 10.1007/978-3-030-82859-2_7
7
Lin Han, Yamei Yan, Meiyang Fan, Shanfeng Gao, Lingyu Zhang, Xiaofan Xiong, Rufeng Li, Xuan Xiao, Xiaofei Wang, Lei Ni, Dongdong Tong, Chen Huang, Youlong Cao, Juan Yang. Pt3R5G inhibits colon cancer cell proliferation through inducing ferroptosis by down-regulating SLC7A11. Life Sciences 2022; 306 doi: 10.1016/j.lfs.2022.120859
8
Yue Zhang, Miao Zeng, Xiaolu Zhang, Qun Yu, Wenyun Zeng, Bin Yu, Jiali Gan, Shiwu Zhang, Xijuan Jiang. Does an apple a day keep away diseases? Evidence and mechanism of action. Food Science & Nutrition 2023; 11(9) doi: 10.1002/fsn3.3487
9
Giulia Baldelli, Mauro De Santi, Daniele Fraternale, Giorgio Brandi, Mirco Fanelli, Giuditta Fiorella Schiavano. Chemopreventive Potential of Apple Pulp Callus Against Colorectal Cancer Cell Proliferation and Tumorigenesis. Journal of Medicinal Food 2019; 22(6) doi: 10.1089/jmf.2018.0188
10
Wasundara Fernando, Rikki F. Clark, H. P. Vasantha Rupasinghe, David W. Hoskin, Melanie R. Power Coombs. Phloridzin Docosahexaenoate Inhibits Spheroid Formation by Breast Cancer Stem Cells and Exhibits Cytotoxic Effects against Paclitaxel-Resistant Triple Negative Breast Cancer Cells. International Journal of Molecular Sciences 2023; 24(19) doi: 10.3390/ijms241914577
11
Mohammad Jalili‐Nik, Arash Soltani, Soussan Moussavi, Majid Ghayour‐Mobarhan, Gordon A. Ferns, Seyed Mahdi Hassanian, Amir Avan. Current status and future prospective of Curcumin as a potential therapeutic agent in the treatment of colorectal cancer. Journal of Cellular Physiology 2018; 233(9) doi: 10.1002/jcp.26368
12
Ying Hu, Xiongjian Wu, Xiaobin Tan, Jingzhi Zhang. Hsa_circRNA_007630 knockdown delays colon cancer progression by modulation of ferroptosis via miR‐506‐3p/AURKA axis. Journal of Biochemical and Molecular Toxicology 2024; 38(8) doi: 10.1002/jbt.23771
13
Dan Zhang, Zhipeng Yu, Wenzhu Zhao, Jingbo Liu. Assessment of the anti-tumor activity of cyanidin-3-O-arabinoside from apple against APN, JAK, and EZH2 target proteins. Food Bioscience 2022; 48 doi: 10.1016/j.fbio.2022.101788
14
Małgorzata Majewska, Urszula Lewandowska. The chemopreventive and anticancer potential against colorectal cancer of polyphenol-rich fruit extracts. Food Reviews International 2018; 34(4) doi: 10.1080/87559129.2017.1307388
15
Aleksandra Kristo, Dorothy Klimis-Zacas, Angelos Sikalidis. Protective Role of Dietary Berries in Cancer. Antioxidants 2016; 5(4) doi: 10.3390/antiox5040037
16
Kuan-Hsun Wu, Chi-Tang Ho, Zhao-Feng Chen, Li-Ching Chen, Jacqueline Whang-Peng, Teng-Nan Lin, Yuan-Soon Ho. The apple polyphenol phloretin inhibits breast cancer cell migration and proliferation via inhibition of signals by type 2 glucose transporter. Journal of Food and Drug Analysis 2018; 26(1) doi: 10.1016/j.jfda.2017.03.009
17
Smita Kapoor, Yogendra S. Padwad. Phloretin induces G2/M arrest and apoptosis by suppressing the β-catenin signaling pathway in colorectal carcinoma cells. Apoptosis 2023; 28(5-6) doi: 10.1007/s10495-023-01826-4
18
Sandip Patra, Priyanka N. Makhal, Shubham Jaryal, Nilesh More, Venkata Rao Kaki. Anthocyanins: Plant-based flavonoid pigments with diverse biological activities. International Journal of Plant Based Pharmaceuticals 2022; 2(1) doi: 10.62313/ijpbp.2022.22
19
Nicola Busatto, Daiki Matsumoto, Alice Tadiello, Urska Vrhovsek, Fabrizio Costa, Ram Roshan Sharma. Multifaceted analyses disclose the role of fruit size and skin-russeting in the accumulation pattern of phenolic compounds in apple. PLOS ONE 2019; 14(7) doi: 10.1371/journal.pone.0219354
20
Saeede Jafari Nasab, Pegah Rafiee, Alireza Bahrami, Nasim Rezaeimanesh, Bahram Rashidkhani, Golbon Sohrab, Farah Naja, Ehsan Hejazi, Amir Sadeghi. Diet-dependent acid load and the risk of colorectal cancer and adenoma: a case–control study. Public Health Nutrition 2021; 24(14) doi: 10.1017/S1368980020003420
21
Manoj Kumar Sarangi, M. E. Bhanoji Rao, Versha Parcha. Smart polymers for colon targeted drug delivery systems: a review. International Journal of Polymeric Materials and Polymeric Biomaterials 2021; 70(16) doi: 10.1080/00914037.2020.1785455
22
Saeede Jafari Nasab, Alireza Bahrami, Pegah Rafiee, Azita Hekmatdoust, Matin Ghanavati, Bahram Rashidkhani, Amir Sadeghi, Hamid Asadzadeh Aghdaei, Farah Naja, Ehsan Hejazi. Healthy Eating Index-2010 and Mediterranean-Style Dietary Pattern Score and the risk of colorectal cancer and adenoma: a case–control study. Nutrition and Cancer 2020; 72(8) doi: 10.1080/01635581.2019.1683212
23
Monika Kalinowska, Ewelina Gołebiewska, Małgorzata Zawadzka, Renata Choińska, Kamila Koronkiewicz, Katarzyna Piasecka-Jóźwiak, Marzena Bujak. Sustainable extraction of bioactive compound from apple pomace through lactic acid bacteria (LAB) fermentation. Scientific Reports 2023; 13(1) doi: 10.1038/s41598-023-46584-0
24
Saikat Dewanjee, Pratik Chakraborty, Abhijit Dey, Hiranmoy Bhattacharya, Chiranjib Bhattacharyya, Rupa Sanyal, Manas Bhowmik. Plant Polysaccharides as Pharmaceutical Excipients. 2023;  doi: 10.1016/B978-0-323-90780-4.00012-7
25
Quinatzin Zafra-Rojas, Nelly Cruz-Cansino, Alma Delgadillo-Ramírez, Ernesto Alanís-García, Javier Añorve-Morga, Aurora Quintero-Lira, Araceli Castañeda-Ovando, Esther Ramírez-Moreno. Organic Acids, Antioxidants, and Dietary Fiber of Mexican Blackberry(Rubus fruticosus)Residues cv. Tupy. Journal of Food Quality 2018; 2018 doi: 10.1155/2018/5950761
26
Li-Yuan Bai, Chang-Fang Chiu, Po-Chen Chu, Wei-Yu Lin, Shih-Jiuan Chiu, Jing-Ru Weng. A triterpenoid from wild bitter gourd inhibits breast cancer cells. Scientific Reports 2016; 6(1) doi: 10.1038/srep22419
27
Haroon Iqbal, Farid Menaa, Naveed Ullah Khan, Anam Razzaq, Zaheer Ullah Khan, Kifayat Ullah, Robia Kamal, Muhammad Sohail, Gobika Thiripuranathar, Bushra Uzair, Nosheen Fatima Rana, Barkat Ali Khan, Bouzid Menaa. Two Promising Anti-Cancer Compounds, 2-Hydroxycinnaldehyde and 2- Benzoyloxycinnamaldehyde: Where do we stand?. Combinatorial Chemistry & High Throughput Screening 2022; 25(5) doi: 10.2174/1386207324666210216094428
28
Jun Tao, Ya Li, Sha Li, Hua-Bin Li. Plant foods for the prevention and management of colon cancer. Journal of Functional Foods 2018; 42 doi: 10.1016/j.jff.2017.12.064
29
Bernardina Scafuri, Anna Marabotti, Virginia Carbone, Paola Minasi, Serena Dotolo, Angelo Facchiano. A theoretical study on predicted protein targets of apple polyphenols and possible mechanisms of chemoprevention in colorectal cancer. Scientific Reports 2016; 6(1) doi: 10.1038/srep32516
30
Magdah A. Ganash. Anticancer potential of ascorbic acid and inorganic selenium on human breast cancer cell line MCF-7 and colon carcinoma HCT-116. Journal of Cancer Research and Therapeutics 2021; 17(1) doi: 10.4103/jcrt.JCRT_989_17
31
Megha Bansal, Neha Singh, Saurabh Pal, Indra Dev, Kausar Mahmood Ansari. . Advances in Molecular Toxicology 2018; 12 doi: 10.1016/B978-0-444-64199-1.00004-X
32
Izabela Koss-Mikołajczyk, Monika Baranowska, Vanja Todorovic, Adriana Albini, Clementina Sansone, Pierre Andreoletti, Mustapha Cherkaoui-Malki, Gérard Lizard, Douglas Noonan, Sladjana Sobajic, Agnieszka Bartoszek. Prophylaxis of Non-communicable Diseases: Why Fruits and Vegetables may be Better Chemopreventive Agents than Dietary Supplements Based on Isolated Phytochemicals?. Current Pharmaceutical Design 2019; 25(16) doi: 10.2174/1381612825666190702093301
33
Lin Han, Yamei Yan, Meiyang Fan, Shanfeng Gao, Lingyu Zhang, Xiaofan Xiong, Rufeng Li, Xuan Xiao, Xiaofei Wang, Lei Ni, Chen Huang, Youlong Cao, Juan Yang. . 2022;  doi: 10.2139/ssrn.4053321
34
Shivraj Hariram Nile, Arti Nile, Junqiu Liu, Doo Hwan Kim, Guoyin Kai. Exploitation of apple pomace towards extraction of triterpenic acids, antioxidant potential, cytotoxic effects, and inhibition of clinically important enzymes. Food and Chemical Toxicology 2019; 131 doi: 10.1016/j.fct.2019.110563
35
Karina Mierczak, Anna Garus-Pakowska. An Overview of Apple Varieties and the Importance of Apple Consumption in the Prevention of Non-Communicable Diseases—A Narrative Review. Nutrients 2024; 16(19) doi: 10.3390/nu16193307
36
Walaa E. Hammam, Amany M. Gad, Mary K. Gad, Farid N. Kirollos, Nemat A. Yassin, Mona Elmahdy El Tantawi, Seham Salah Eldin El Hawary. Pyrus communis L. (Pear) and Malus domestica Borkh. (apple) leaves lipoidal extracts as sources for beta-sitosterol rich formulae and their wound healing evaluation. Natural Product Research 2023; 37(15) doi: 10.1080/14786419.2022.2056181
37
Bhushan R. Rane, Rutuja R. Patil, Ashish S. Jain, Raj K. Keservani, Rajesh K. Kesharwani. Nutraceuticals and Functional Foods in Immunomodulators. 2022;  doi: 10.1007/978-981-19-2507-8_7
38
R. Sunitha, S. Madhavi Latha, M. Pavani, D. Durga Siva Prasad, Shaik Inthiyaz. Medicinal Herbs for Treating Colorectal Cancer – A Comprehensive Review. Research Journal of Pharmacognosy and Phytochemistry 2025;  doi: 10.52711/0975-4385.2025.00026
39
Sheng-Tsai Lin, Shih-Hsin Tu, Po-Sheng Yang, Sung-Po Hsu, Wei- Hwa Lee, Chi-Tang Ho, Chih-Hsiung Wu, Yu-Hsin Lai, Ming-Yao Chen, Li-Ching Chen. Apple Polyphenol Phloretin Inhibits Colorectal Cancer Cell Growth via Inhibition of the Type 2 Glucose Transporter and Activation of p53-Mediated Signaling. Journal of Agricultural and Food Chemistry 2016; 64(36) doi: 10.1021/acs.jafc.6b02861
40
Katarzyna Owczarek, Urszula Lewandowska. The Impact of Dietary Polyphenols on COX-2 Expression in Colorectal Cancer. Nutrition and Cancer 2017; 69(8) doi: 10.1080/01635581.2017.1367940
41
Tharani Devi Natarajan, Janci Rani Ramasamy, Kirthika Palanisamy. Nutraceutical potentials of synergic foods: a systematic review. Journal of Ethnic Foods 2019; 6(1) doi: 10.1186/s42779-019-0033-3
42
Pasquale Perrone, Chiara De Rosa, Stefania D’Angelo. Mediterranean Diet and Agri-Food By-Products: A Possible Sustainable Approach for Breast Cancer Treatment. Antioxidants 2025; 14(7) doi: 10.3390/antiox14070789
43
Dariusz Włodarek, Hubert Dobrowolski. Fantastic Foods and Where to Find Them—Advantages and Disadvantages of Nutri-Score in the Search for Healthier Food. Nutrients 2022; 14(22) doi: 10.3390/nu14224843
44
Kang LI, Dawei YUAN, Wei CHEN, Rulan MA, Yinsheng XIAN. (S)-(-)-N-[2-(3-Hydroxy-2-oxo-2,3-dihydro-1H-indol-3-yl)-ethyl]-acetamide inhibits colon cancer growth via the STAT1 pathway. Food Science and Technology 2022; 42 doi: 10.1590/fst.49121
45
Urszula Szymanowska, Monika Karaś, Anna Jakubczyk, Janusz Kocki, Rafał Szymanowski, Ireneusz Tomasz Kapusta. Raspberry Pomace as a Good Additive to Apple Freeze-Dried Fruit Bars: Biological Properties and Sensory Evaluation. Molecules 2024; 29(23) doi: 10.3390/molecules29235690
46
R. Sunitha, S. Madhavi Latha, M. Pavani, D. Durga Siva Prasad, Shaik Inthiyaz. Medicinal Herbs for Treating Colorectal Cancer – A Comprehensive Review. Asian Journal of Pharmaceutical Research 2025;  doi: 10.52711/2231-5691.2025.00032
47
Paula Rossini Augusti, Andréia Quatrin, Renius Mello, Vivian Caetano Bochi, Eliseu Rodrigues, Inês D. Prazeres, Ana Catarina Macedo, Sheila Cristina Oliveira-Alves, Tatiana Emanuelli, Maria Rosário Bronze, Ana Teresa Serra. Antiproliferative Effect of Colonic Fermented Phenolic Compounds from Jaboticaba (Myrciaria trunciflora) Fruit Peel in a 3D Cell Model of Colorectal Cancer. Molecules 2021; 26(15) doi: 10.3390/molecules26154469
48
Wafa S. Alansari, Areej A. Eskandrani. The Anticarcinogenic Effect of the Apple Polyphenol Phloretin in an Experimental Rat Model of Hepatocellular Carcinoma. Arabian Journal for Science and Engineering 2020; 45(6) doi: 10.1007/s13369-020-04478-7
49
Shih-Hsin Tu, Li-Ching Chen, Yuan-Soon Ho. An apple a day to prevent cancer formation: Reducing cancer risk with flavonoids. Journal of Food and Drug Analysis 2017; 25(1) doi: 10.1016/j.jfda.2016.10.016
50
Kumars Jovaini, Seyed Amir Mohammad Mortazavian Farsani, Seyed Hamid Aghaee-Bakhtiari, Sahar Baniyaghoob. Miracle drink supplemented with Lactobacillus bulgaricus loaded-chitosan/alginate nanoparticles as a medicinal food for control of MCF7 cancer cells. Electronic Journal of Biotechnology 2024; 70 doi: 10.1016/j.ejbt.2024.04.002
51
Cíntia Ferreira-Pêgo, Bojana B. Vidović, Nuno G. Oliveira, Ana S. Fernandes, João G. Costa. Cancer. 2021;  doi: 10.1016/B978-0-12-819547-5.00021-3
52
Mukesh Singh Sikarwar, Vaibhav Kumar Rathi. Traditional Resources and Tools for Modern Drug Discovery. Interdisciplinary Biotechnological Advances 2024;  doi: 10.1007/978-981-97-4600-2_12
53
54
Emanuela Pasculli, Marica Cariello, Maria Arconzo, Carla Gualtieri, Anca Macovei, Silvia Cultrera, Raffaella Maria Gadaleta, Elena Piccinin, Antonio Moschetta, Wenxing Li. Apple-derived miR-482a-3p decreases c-MYB expression and proliferation of human intestinal cell lines. PLOS One 2026; 21(4) doi: 10.1371/journal.pone.0347565
55
Fu-Sheng Gao, Yu-Tao Zhan, Xu-Dong Wang, Chuan Zhang. Enhancement of anti-tumor effect of plasmid DNA-carrying MUC1 by the adjuvanticity of FLT3L in mouse model. Immunopharmacology and Immunotoxicology 2018; 40(4) doi: 10.1080/08923973.2018.1498099
56
Cheryl Chung, Thananunt Rojanasasithara, William Mutilangi, David Julian McClements. Enhanced stability of anthocyanin-based color in model beverage systems through whey protein isolate complexation. Food Research International 2015; 76 doi: 10.1016/j.foodres.2015.07.003
57
Saeede Jafari Nasab, Matin Ghanavati, Pegah Rafiee, Alireza Bahrami, Nazanin Majidi, Cain C. T. Clark, Amir Sadeghi, Mohammad Houshyari, Ehsan Hejazi. A case-control study of Dietary Approaches to Stop Hypertension (DASH) diets, colorectal cancer and adenomas among Iranian population. BMC Cancer 2021; 21(1) doi: 10.1186/s12885-021-08786-5