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For: Lee CS, Ryan EJ, Doherty GA. Gastro-intestinal toxicity of chemotherapeutics in colorectal cancer: The role of inflammation. World J Gastroenterol 2014; 20(14): 3751-3761 [PMID: 24744571 DOI: 10.3748/wjg.v20.i14.3751]
URL: https://www.wjgnet.com/1007-9327/full/v20/i14/3751.htm
Number Citing Articles
1
Kaïs Rtibi, Slimen Selmi, Dhekra Grami, Hichem Sebai, Mohamed Amri, Lamjed Marzouki. Irinotecan chemotherapy-induced intestinal oxidative stress: Underlying causes of disturbed mucosal water and electrolyte transport. Pathophysiology 2017; 24(4) doi: 10.1016/j.pathophys.2017.07.002
2
Erika Cecchin, Elena De Mattia, Eva Dreussi, Marcella Montico, Elisa Palazzari, Federico Navarria, Francesca Bergamo, Claudio Belluco, Luca Quartuccio, Salvatore De Vita, Vincenzo Canzonieri, Sara Gagno, Chiara Zanusso, Angela Buonadonna, Salvatore Pucciarelli, Antonino De Paoli, Giuseppe Toffoli. Immunogenetic markers in IL17F predict the risk of metastases spread and overall survival in rectal cancer patients treated with neoadjuvant chemoradiotherapy. Radiotherapy and Oncology 2020; 149 doi: 10.1016/j.radonc.2020.04.055
3
Ritu Raina, Ravinder Bhatt, Arif Hussain. Chrysin targets aberrant molecular signatures and pathways in carcinogenesis (Review). World Academy of Sciences Journal 2024; 6(5) doi: 10.3892/wasj.2024.260
4
Stefanie Hoffmann, Philip Hewitt, Isabel Koscielski, Dorota Kurek, Wouter Strijker, Kinga Kosim. Validation of an MPS-based intestinal cell culture model for the evaluation of drug-induced toxicity. Frontiers in Drug Discovery 2025; 4 doi: 10.3389/fddsv.2024.1459424
5
K. Beukers, M.T.A. Strous, F.J. Vogelaar, A.J. van de Wouw, R.C. Havermans, M.L.G. Janssen-Heijnen. The modified Glasgow prognostic score as inflammation-based nutritional assessment for systemic treatment tolerance in patients with colorectal cancer. Clinical Nutrition Open Science 2026; 67 doi: 10.1016/j.nutos.2026.100670
6
Camila Fernandes, Carlos Wagner Souza Wanderley, Camila Meireles Souza Silva, Heitor Amorim Muniz, Maraiza Alves Teixeira, Nathália Ribeiro Pinho Souza, André George Ferreira Cândido, Renata Brito Falcão, Marcellus Henrique Loiola Ponte Souza, Paulo Roberto Carvalho Almeida, Lilia Maria Carneiro Câmara, Roberto César Pereira Lima-Júnior. Role of regulatory T cells in irinotecan-induced intestinal mucositis. European Journal of Pharmaceutical Sciences 2018; 115 doi: 10.1016/j.ejps.2018.01.006
7
Adebisi Adeleke, Amusa S. Adebayo, Kafilat Agbaje, Oluwabukunmi Olajubutu, Simeon K. Adesina. Colorectal Cancer: Therapeutic Approaches and Their Complications. Biomedicines 2025; 13(7) doi: 10.3390/biomedicines13071646
8
Giuseppe L. Banna, Francesco Torino, Francesco Marletta, Maria Santagati, Rossella Salemi, Elisa Cannarozzo, Luca Falzone, Francesco Ferraù, Massimo Libra. Lactobacillus rhamnosus GG: An Overview to Explore the Rationale of Its Use in Cancer. Frontiers in Pharmacology 2017; 8 doi: 10.3389/fphar.2017.00603
9
Yin Yixia, Jirapas Sripetchwandee, Nipon Chattipakorn, Siriporn C. Chattipakorn. The alterations of microbiota and pathological conditions in the gut of patients with colorectal cancer undergoing chemotherapy. Anaerobe 2021; 68 doi: 10.1016/j.anaerobe.2021.102361
10
Ebrahim Rahmani Moghadam, Hui Li Ang, Sholeh Etehad Asnaf, Amirhossein Zabolian, Hossein Saleki, Mohammad Yavari, Hossein Esmaeili, Ali Zarrabi, Milad Ashrafizadeh, Alan Prem Kumar. Broad-Spectrum Preclinical Antitumor Activity of Chrysin: Current Trends and Future Perspectives. Biomolecules 2020; 10(10) doi: 10.3390/biom10101374
11
Silvia H. S. P. Pedroso, Angélica T. Vieira, Rafael W. Bastos, Jamil S. Oliveira, Christiane T. Cartelle, Rosa M. E. Arantes, Pedro M. G. Soares, Simone V. Generoso, Valbert N. Cardoso, Mauro M. Teixeira, Jacques R. Nicoli, Flaviano S. Martins. Evaluation of mucositis induced by irinotecan after microbial colonization in germ-free mice.  Microbiology 2015; 161(10) doi: 10.1099/mic.0.000149
12
Daiva Dabkeviciene, Violeta Jonusiene, Vilmante Zitkute, Egle Zalyte, Pranas Grigaitis, Vida Kirveliene, Ausra Sasnauskiene. The role of interleukin-8 (CXCL8) and CXCR2 in acquired chemoresistance of human colorectal carcinoma cells HCT116. Medical Oncology 2015; 32(12) doi: 10.1007/s12032-015-0703-y
13
Jun‐nan Hu, Yi‐ming Wang, Hao Zhang, Hui‐ping Li, Zi Wang, Mei Han, Shen Ren, Shan Tang, Shuang Jiang, Wei Li. Schisandra B, a representative lignan from Schisandra chinensis, improves cisplatin‐induced toxicity: An in vitro study. Phytotherapy Research 2023; 37(2) doi: 10.1002/ptr.7644
14
Martina Rebersek, Tanja Mesti, Marko Boc, Janja Ocvirk. Molecular biomarkers and histological parameters impact on survival and response to first- line systemic therapy of metastatic colorectal cancer patients. Radiology and Oncology 2019; 53(1) doi: 10.2478/raon-2019-0013
15
Sang‑Mi Woo, Kang Lee, Gyu Lee, Ji Park, Hee Lee, Hyo‑Jung Bahn, Hyun Yoon, Jem Kim, Young Shin, Sung‑Gook Cho, Seong‑Gyu Ko. Novel herbal medicine LA16001 ameliorates cisplatin-induced anorexia. Molecular Medicine Reports 2017;  doi: 10.3892/mmr.2017.8176
16
John Shumar, Zachary Junga, Jeptha T Johnson, Lawrence Goldkind. Treatment-resistant severe capecitabine-induced diarrhoea resolved with oral budesonide. BMJ Case Reports 2019; 12(11) doi: 10.1136/bcr-2019-231544
17
Claire J. Han, Xia Ning, Christin E. Burd, Daniel J. Spakowicz, Fode Tounkara, Matthew F. Kalady, Anne M. Noonan, Susan McCabe, Diane Von Ah. Chemotoxicity and Associated Risk Factors in Colorectal Cancer: A Systematic Review and Meta-Analysis. Cancers 2024; 16(14) doi: 10.3390/cancers16142597
18
Luyao Tian, Xia Li, Haixia Ji, Qing Yu, Mingjuan Yang, Lanping Guo, Luqi Huang, Wenyuan Gao. Melanin-like nanoparticles: advances in surface modification and tumour photothermal therapy. Journal of Nanobiotechnology 2022; 20(1) doi: 10.1186/s12951-022-01698-x
19
Dongze Qin, Wenhui Fu, Yi Sun, Lingda Zhao, Haiwei Liu, Dancai Fan, Dongfei Tan, Xuemeng Ji, Shuo Wang. Protective Effects of Cereal-Based Fermented Beverages Against 5-Fluorouracil-Induced Intestinal Damage in Mice. Nutrients 2024; 16(24) doi: 10.3390/nu16244332
20
Ran Zhang, Xue-Qing Song, Rui-Ping Liu, Zhong-Ying Ma, Jing-Yuan Xu. Fuplatin: An Efficient and Low-Toxic Dual-Prodrug. Journal of Medicinal Chemistry 2019; 62(9) doi: 10.1021/acs.jmedchem.9b00128
21
Halyna M. Kuznietsova, Valentyna K. Luzhenetska, Iryna P. Kotlyar, Volodymyr K. Rybalchenko, Péter Krajcsi. Effects of 5‐Amyno‐4‐(1,3‐benzothyazol‐2‐yn)‐1‐(3‐methoxyphenyl)‐1,2‐dihydro‐3H‐pyrrol‐3‐one Intake on Digestive System in a Rat Model of Colon Cancer. The Scientific World Journal 2015; 2015(1) doi: 10.1155/2015/376576
22
Richard A. Forsgård, Vannina G. Marrachelli, Katri Korpela, Rafael Frias, Maria Carmen Collado, Riitta Korpela, Daniel Monleon, Thomas Spillmann, Pia Österlund. Chemotherapy-induced gastrointestinal toxicity is associated with changes in serum and urine metabolome and fecal microbiota in male Sprague–Dawley rats. Cancer Chemotherapy and Pharmacology 2017; 80(2) doi: 10.1007/s00280-017-3364-z
23
Shoma Mikawa, Makoto Kondo, Noriyuki Kaji, Taiki Mihara, Ryohei Yoshitake, Takayuki Nakagawa, Masaya Takamoto, Ryohei Nishimura, Shoichi Shimada, Hiroshi Ozaki, Masatoshi Hori. Serotonin 3 receptor signaling regulates 5‐fluorouracil‐mediated apoptosis indirectly via TNF‐α production by enhancing serotonin release from enterochromaffin cells. The FASEB Journal 2019; 33(2) doi: 10.1096/fj.201701200RR
24
Anna Maria Mileo, Paola Nisticò, Stefania Miccadei. Polyphenols: Immunomodulatory and Therapeutic Implication in Colorectal Cancer. Frontiers in Immunology 2019; 10 doi: 10.3389/fimmu.2019.00729
25
Silvia Vivarelli, Luca Falzone, Maria Basile, Daria Nicolosi, Carlo Genovese, Massimo Libra, Mario Salmeri. Benefits of using probiotics as adjuvants in anticancer therapy (Review). World Academy of Sciences Journal 2019;  doi: 10.3892/wasj.2019.13
26
Omar Bougandoura, Yahia Achour, Abdelhalim Zaoui. Electroporation in Cancer Therapy: A Simplified Model Derived from the Hodgkin–Huxley Model. Bioelectricity 2024; 6(3) doi: 10.1089/bioe.2023.0045
27
Harbinder Singh, Nihar Kinarivala, Sahil Sharma. Multi-Targeting Anticancer Agents: Rational Approaches, Synthetic Routes and Structure Activity Relationship. Anti-Cancer Agents in Medicinal Chemistry 2019; 19(7) doi: 10.2174/1871520619666190118120708
28
Camila Fernandes, Mahara Coelho Crisostomo Miranda, Cássia Rodrigues Roque, Ana Lizeth Padilla Paguada, Carlos Adrian Rodrigues Mota, Katharine Gurgel Dias Florêncio, Anamaria Falcão Pereira, Deysi Viviana Tenazoa Wong, Reinaldo Barreto Oriá, Roberto César Pereira Lima-Júnior. Is There an Interplay between Environmental Factors, Microbiota Imbalance, and Cancer Chemotherapy-Associated Intestinal Mucositis?. Pharmaceuticals 2024; 17(8) doi: 10.3390/ph17081020
29
Audra L. Andrew, Daren C. Card, Robert P. Ruggiero, Drew R. Schield, Richard H. Adams, David D. Pollock, Stephen M. Secor, Todd A. Castoe. Rapid changes in gene expression direct rapid shifts in intestinal form and function in the Burmese python after feeding. Physiological Genomics 2015; 47(5) doi: 10.1152/physiolgenomics.00131.2014
30
Binbin Ye, Ruifang Zhang, Yihong Xian, Xiuxiu Liao, Weijian Chen, Ke Nie. Forsythiae Fructus attenuates cisplatin-induced cytotoxicity in IEC-6 ​cells and J774A.1 macrophages by inhibiting NLRP3/caspase-1/GSDMD mediated pyroptosis. Journal of Holistic Integrative Pharmacy 2023; 4(2) doi: 10.1016/j.jhip.2023.09.001
31
Winnie M. C. van den Boogaard, Daphne S. J. Komninos, Wilbert P. Vermeij. Chemotherapy Side-Effects: Not All DNA Damage Is Equal. Cancers 2022; 14(3) doi: 10.3390/cancers14030627
32
Huiyun Shi, Ying Chen, Qianqian Guo, Ling Tao, Xingjie Wu, Xiangchun Shen, Wen Liu. Dual-drug loaded hybrid nanoparticle for combined tumor cocktail chemo-photothermal therapy and anti-inflammation. Journal of Drug Delivery Science and Technology 2023; 82 doi: 10.1016/j.jddst.2023.104312
33
Reza Norouzirad, Khashayar Zahedi, Mohammad Mehdi Behvandi, Abbas Moridnia, Susan Sabbagh, Phuping Sucharitakul. Mitigation of Methotrexate‐Induced Intestinal Mucositis in Male Wistar Rats by Gallic Acid: The Role of HGF and C‐Met Genes. Journal of Toxicology 2025; 2025(1) doi: 10.1155/jt/9990692
34
Wei Peng, Xinxin Fan, Hongrui Shi, Yixuan Jiang, Liang Fan, Yan Xing, Yuzan Peng, Yuling He, Wei Zou, Mei Jiang. Gut Microbiota and Chemotherapy-Induced Gastrointestinal Toxicity: Mechanisms and Intervention Strategies. Digestive Diseases 2025; 44(1) doi: 10.1159/000548922
35
Arkadiusz Czerwonka, Marta K. Lemieszek, Monika Karpińska, Joanna Matysiak, Andrzej Niewiadomy, Wojciech Rzeski. Evaluation of the effect of 2-(2,4-dihydroxyphenyl)-4H-benzofuro[3,2-d][1,3]thiazin-4-one on colon cells and its anticancer potential. Medicinal Chemistry Research 2018; 27(9) doi: 10.1007/s00044-018-2223-8
36
Takanori Yamaguchi, Arong Gaowa, Eun Jeong Park, Isao Tawara, Motomu Shimaoka. Recombinant soluble thrombomodulin attenuates cisplatin-induced intestinal injury by inhibiting intestinal epithelial cell-derived cytokine secretion. Molecular Biology Reports 2023; 50(10) doi: 10.1007/s11033-023-08762-1
37
Zhou Chen, Xiaoshuang Xu, Lianhua Piao, Shan Chang, Jiyong Liu, Ren Kong. Identify old drugs as selective bacterial β‐GUS inhibitors by structural‐based virtual screening and bio‐evaluations. Chemical Biology & Drug Design 2020; 95(3) doi: 10.1111/cbdd.13655
38
Quynh Nhu Nguyen-Trinh, Kim Xuyen Thi Trinh, Nhu-Thuy Trinh, Van Toi Vo, Nan Li, Yukio Nagasaki, Long Binh Vong. A silica-based antioxidant nanoparticle for oral delivery of Camptothecin which reduces intestinal side effects while improving drug efficacy for colon cancer treatment. Acta Biomaterialia 2022; 143 doi: 10.1016/j.actbio.2022.02.036
39
40
Jonathan Escalante, Rachel M. McQuade, Vanesa Stojanovska, Kulmira Nurgali. Impact of chemotherapy on gastrointestinal functions and the enteric nervous system. Maturitas 2017; 105 doi: 10.1016/j.maturitas.2017.04.021
41
Jing Li, Qianqian Yu, Shengling Fu, Min Xu, Tao Zhang, Conghua Xie, Jueping Feng, Jigui Chen, Aihua Zang, Yixin Cai, Qiang Fu, Shan Liu, Mingsheng Zhang, Qiu Hong, Liu Huang, Xianglin Yuan. A novel genetic score model of UGT1A1 and TGFB pathway as predictor of severe irinotecan-related diarrhea in metastatic colorectal cancer patients. Journal of Cancer Research and Clinical Oncology 2016; 142(7) doi: 10.1007/s00432-016-2176-6
42
Ahmed Abdel Moneim, Ana Guerra-Librero, Javier Florido, Ying-Qiang Shen, Beatriz Fernández-Gil, Darío Acuña-Castroviejo, Germaine Escames. Oral Mucositis: Melatonin Gel an Effective New Treatment. International Journal of Molecular Sciences 2017; 18(5) doi: 10.3390/ijms18051003
43
Po-Lin Liao, Shih-Hsuan Huang, Chien-Hung Hung, Wei-Kuang Huang, Chi-Hao Tsai, Jaw-Jou Kang, Hui-Po Wang, Yu-Wen Cheng. Efficacy of Azatyrosine-Phenylbutyric Hydroxamides, a Histone Deacetylase Inhibitor, on Chemotherapy-Induced Gastrointestinal Mucositis. International Journal of Molecular Sciences 2019; 20(2) doi: 10.3390/ijms20020249
44
Kaïs Rtibi, Lamjed Marzouki, Hichem Sebai. Toxicology. 2021;  doi: 10.1016/B978-0-12-819092-0.00028-5
45
Jui-Ling Wang, Yu-Siang Chen, Kuo-Chin Huang, Chin-Hsing Yeh, Miles Chih-Ming Chen, Lawrence Shih-Hsin Wu, Yi-Han Chiu. Resistant Starch-Encapsulated Probiotics Attenuate Colorectal Cancer Cachexia and 5-Fluorouracil-Induced Microbial Dysbiosis. Biomedicines 2024; 12(7) doi: 10.3390/biomedicines12071450
46
Doaa Ibrahim, Safaa I. Khater, Ahmed Abdelfattah-Hassan, Leena S. Alqahtani, Aya Sh. Metwally, Shefaa M. Bazeed, Aya Elgamal, Nagwa I. Sheraiba, Elham M. Hussein, Fatmah Ali Alasmary, Gamal A. Salem, Mohamed Ali, Hala Mahfouz. Prospects of new targeted nanotherapy combining liponiosomes with berberine to combat colorectal cancer development: An in vivo experimental model. International Journal of Pharmaceutics 2023; 647 doi: 10.1016/j.ijpharm.2023.123511
47
Zicong Zheng, Songpol Srinual, Jie Chen, Li Li, Ting Du, Ming Hu, Rongjin Sun, Song Gao. Herbal Medicines as Adjuvants for the Treatment of Chemotherapy-Induced Diarrhea. Current Drug Metabolism 2023; 24(6) doi: 10.2174/1389200224666230817102224
48
Brandon N. VanderVeen, Alexander T. Sougiannis, Kandy T. Velazquez, James A. Carson, Daping Fan, E. Angela Murphy. The Acute Effects of 5 Fluorouracil on Skeletal Muscle Resident and Infiltrating Immune Cells in Mice. Frontiers in Physiology 2020; 11 doi: 10.3389/fphys.2020.593468
49
Joleen M. Hubbard, Axel Grothey. Napabucasin: An Update on the First-in-Class Cancer Stemness Inhibitor. Drugs 2017; 77(10) doi: 10.1007/s40265-017-0759-4
50
Nitya Devisetti, Pushti Shah, Farrah C. Liu. From Mechanisms to Treatment: A Comprehensive View of Lymphatic Metastasis in Cancer. Lymphatics 2025; 3(2) doi: 10.3390/lymphatics3020012
51
Cristina Trejo-Solís, Irma Susana Rojas-Tomé, Helgi Jung-Cook, Francisca Palomares-Alonso. Melatonin combined with antineoplastic drugs or natural products for cancer treatment: An update. Current Research in Pharmacology and Drug Discovery 2025; 9 doi: 10.1016/j.crphar.2025.100239
52
Luyu Qi, Qun Luo, Yanyan Zhang, Feifei Jia, Yao Zhao, Fuyi Wang. Advances in Toxicological Research of the Anticancer Drug Cisplatin. Chemical Research in Toxicology 2019; 32(8) doi: 10.1021/acs.chemrestox.9b00204
53
Miaomiao Hu, Xiaoli Wu, Meng Luo, Hua Wei, Di Xu, Feng Xu. Lactobacillus rhamnosus FLRH93 protects against intestinal damage in mice induced by 5-fluorouracil. Journal of Dairy Science 2020; 103(6) doi: 10.3168/jds.2019-17836
54
Ching-Wei Chang, Chia-Yuan Liu, Hung-Chang Lee, Yen-Hua Huang, Li-Hui Li, Jen-Shiu Chiang Chiau, Tsang-En Wang, Cheng-Hsin Chu, Shou-Chuan Shih, Tung-Hu Tsai, Yu-Jen Chen. Lactobacillus casei Variety rhamnosus Probiotic Preventively Attenuates 5-Fluorouracil/Oxaliplatin-Induced Intestinal Injury in a Syngeneic Colorectal Cancer Model. Frontiers in Microbiology 2018; 9 doi: 10.3389/fmicb.2018.00983
55
Faaiza Shahid, Zeba Farooqui, Farah Khan. Cisplatin-induced gastrointestinal toxicity: An update on possible mechanisms and on available gastroprotective strategies. European Journal of Pharmacology 2018; 827 doi: 10.1016/j.ejphar.2018.03.009
56
Zi-Wen Chen, Tao Xu, Zi-Han Yin, Qi-fu Li, Yun-Jie Shu, Xue-Li Zhou, Ling Zhao, Ming-Sheng Sun, Fan-Rong Liang. Electroacupuncture for chemotherapy-induced gastrointestinal symptoms in colorectal cancer: protocol for a multicenter, three-arm, randomized controlled trial. International Journal of Colorectal Disease 2025; 40(1) doi: 10.1007/s00384-025-05008-3
57
Thiago Vinicius Ávila, Zélia Menezes-Garcia, Raquel Duque do Nascimento Arifa, Frederico Marianetti Soriani, Alexandre de Magalhães Vieira Machado, Mauro Martins Teixeira, Caio Tavares Fagundes, Daniele G. Souza. Mitochondrial DNA as a Possible Ligand for TLR9 in Irinotecan-induced Small Intestinal Mucositis. Immunological Investigations 2022; 51(6) doi: 10.1080/08820139.2022.2026379
58
Zahra Amirkhanzadeh Barandouzi, Claire Rowcliffe, Julia Schrogin, Rebecca Meador, Deborah Watkins Bruner. Exploring the links among inflammation and gut microbiome with psychoneurological symptoms and gastrointestinal toxicities in gynecologic cancers: a systematic review. Supportive Care in Cancer 2022; 30(8) doi: 10.1007/s00520-022-07027-0
59
Nouman Ali, Roman Akbar, Amna Saleem, Adeeba Ali, Aamir Ali. AI based natural inhibitor targeting RPS20 for colorectal cancer treatment using integrated computational approaches. Scientific Reports 2025; 15(1) doi: 10.1038/s41598-025-07574-6
60
Rachel M. McQuade, Maryam Al Thaalibi, Kulmira Nurgali. Impact of chemotherapy-induced enteric nervous system toxicity on gastrointestinal mucositis. Current Opinion in Supportive & Palliative Care 2020; 14(3) doi: 10.1097/SPC.0000000000000515
61
Yueh-Ming Lin, Chih-I Chen, Yi-Ping Hsiang, Yung-Chia Hsu, Kung-Chuan Cheng, Pei-Hsuan Chien, Hsiao-Lin Pan, Chien-Chang Lu, Yun-Ju Chen. Chrysin Attenuates Cell Viability of Human Colorectal Cancer Cells through Autophagy Induction Unlike 5-Fluorouracil/Oxaliplatin. International Journal of Molecular Sciences 2018; 19(6) doi: 10.3390/ijms19061763
62
Vlasta Demeckova, Dagmar Mudronova, Sona Gancarcikova, Peter Kubatka, Karol Kajo, Monika Kassayova, Bianka Bojkova, Marian Adamkov, Peter Solár. 5-Fluorouracil Treatment of CT26 Colon Cancer Is Compromised by Combined Therapy with IMMODIN. International Journal of Molecular Sciences 2022; 23(12) doi: 10.3390/ijms23126374
63
Daniel F. Carr, Seyoum Ayehunie, Andrea Davies, Carrie A. Duckworth, Stephanie French, Neil Hall, Syed Hussain, Howard R. Mellor, Alan Norris, B. Kevin Park, Alexander Penrose, D. Mark Pritchard, Chris S. Probert, Shashi Ramaiah, Claire Sadler, Michael Schmitt, Alison Shaw, James E. Sidaway, Robert G. Vries, Matthew Wagoner, Munir Pirmohamed. Towards better models and mechanistic biomarkers for drug-induced gastrointestinal injury. Pharmacology & Therapeutics 2017; 172 doi: 10.1016/j.pharmthera.2017.01.002
64
Sandra Kalthoff, Stefan Paulusch, Alexander Rupp, Stefan Holdenrieder, Gunther Hartmann, Christian P. Strassburg. The coffee ingredients caffeic acid and caffeic acid phenylethyl ester protect against irinotecan‐induced leukopenia and oxidative stress response. British Journal of Pharmacology 2020; 177(18) doi: 10.1111/bph.15162
65
H Gou, LY Gu, BZ Shang, Y Xiong, C Wang. Protective effect of Bu-Zhong-Yi-Qi decoction, the water extract of Chinese traditional herbal medicine, on 5-fluorouracil-induced intestinal mucositis in mice. Human & Experimental Toxicology 2016; 35(12) doi: 10.1177/0960327115627686
66
Yanzhao Ji, Weidong Zhou, Wei Tan, Zewei Chen, Hanqi Lu, Yanting You, Chunyang Tian, Xinghong Zhou, Lin Zhou, Ren Luo, Xiaoshan Zhao. Protective effect of polysaccharides isolated from the seeds of Cuscuta chinensis Lam. on 5-fluorouracil-induced intestinal mucositis in mice. Acta Cirúrgica Brasileira 2022; 37(2) doi: 10.1590/acb370204
67
Dickson Pius Wande, Yue Qiu, Shijie Chen, Lan Yao, Yanghui Xu, Jing Yao, Hui Xiong. Modified chitosan nanogel-polymersomes for oral co-delivery of oxaliplatin and rapamycin for synergistic chemotherapy. Journal of Drug Delivery Science and Technology 2022; 77 doi: 10.1016/j.jddst.2022.103852
68
Niels Klaassen-Dekker, Ben J. M. Witteman, N. Tjarda van Heek, Flip M. Kruyt, Eva Valgaeren, Elske C. Gootjes, Heidi Rütten, Pieter van ‘t Veer, Renate M. Winkels, Fränzel J. B. van Duijnhoven, Johannes H. W. de Wilt, Ellen Kampman, Dieuwertje E. Kok. Bowel-Related Symptoms and Dietary Fiber Intake in Colorectal Cancer Survivors. JAMA Network Open 2025; 8(11) doi: 10.1001/jamanetworkopen.2025.42147
69
Viviane Lima Batista, Tales Fernando da Silva, Luís Cláudio Lima de Jesus, Nina Dias Coelho-Rocha, Fernanda Alvarenga Lima Barroso, Laisa Macedo Tavares, Vasco Azevedo, Pamela Mancha-Agresti, Mariana Martins Drumond. Probiotics, Prebiotics, Synbiotics, and Paraprobiotics as a Therapeutic Alternative for Intestinal Mucositis. Frontiers in Microbiology 2020; 11 doi: 10.3389/fmicb.2020.544490
70
Daniela Arcos, Ding Quan Ng, Yu Ke, Yi Long Toh, Alexandre Chan. Prediction of gastrointestinal symptoms trajectories using omega-3 and inflammatory biomarkers in early-stage breast cancer patients receiving chemotherapy. Supportive Care in Cancer 2024; 32(1) doi: 10.1007/s00520-023-08274-5
71
Monireh Ganjali, Mansoureh Ganjali, Mohammad Mahdi Adib Sereshki, Navid Ahmadinasab, Arash Ghalandarzadeh, Alaa A.A. Aljabali, Ahmed Barhoum. Bionanotechnology : Emerging Applications of Bionanomaterials. 2022;  doi: 10.1016/B978-0-12-823915-5.00015-0
72
Vanesa Stojanovska, Rachel M. McQuade, Sarah Fraser, Monica Prakash, Shakuntla Gondalia, Rhian Stavely, Enzo Palombo, Vasso Apostolopoulos, Samy Sakkal, Kulmira Nurgali, Mathias Chamaillard. Oxaliplatin-induced changes in microbiota, TLR4+ cells and enhanced HMGB1 expression in the murine colon. PLOS ONE 2018; 13(6) doi: 10.1371/journal.pone.0198359
73
Ogochukwu Izuegbuna. Combating Malnutrition through Sustainable Approaches. 2023;  doi: 10.5772/intechopen.104428
74
Anouk E.C. Bruijnzeels, Floortje Mols, Katrijn Van Deun, Dounya Schoormans. Effects of Cancer Treatment on Inflammation in Colorectal Cancer Patients: A Longitudinal Study. Clinical Colorectal Cancer 2026; 25(1) doi: 10.1016/j.clcc.2025.12.001
75
Siyue He, Zhiwei Wang, Jing Xia, Huijie Jia, Qianlong Dai, Cui Chen, Fei He, Xiaobo Wang, Min Zhou. Dasabuvir alleviates 5-fluorouracil-induced intestinal injury through anti-senescence and anti-inflammatory. Scientific Reports 2024; 14(1) doi: 10.1038/s41598-024-66771-x
76
Martina Gambron, Elena Peruzzi, Samantha Perfler, Marcella Montico, Riccardo Cecchin, Elena De Mattia, Michele Spina, Camilla Lisanti, Serena Corsetti, Luisa Foltran, Fabio Puglisi, Rossana Roncato, Erika Cecchin. DPYD and UGT1A1 Genotype‐Based Dosing for Fluoropyrimidines and Irinotecan Chemotherapy: Variant‐Specific Impact on Treatment Intensity and Toxicity. International Journal of Cancer 2026; 159(10) doi: 10.1002/ijc.70580
77
Chengcheng Guan, Xintong Zhou, Huayao Li, Xiaoran Ma, Jing Zhuang. NF-κB inhibitors gifted by nature: The anticancer promise of polyphenol compounds. Biomedicine & Pharmacotherapy 2022; 156 doi: 10.1016/j.biopha.2022.113951
78
Marwa Awad Abdel Hamid Ibrahim, Walaa M. Elwan. Effect of irinotecan on the tongue mucosa of juvenile male albino rat at adulthood. International Journal of Experimental Pathology 2019; 100(4) doi: 10.1111/iep.12333
79
Shaukat Ali, Mahnoor Arshad, Muhammad Summer, Maryam Zulfiqar, Shehzeen Noor, Laiba Nazakat, Muhammad Abdullah Javed. Recent developments on checkpoint inhibitors, CAR T cells, and beyond for T cell-based immunotherapeutic strategies against cancer. Journal of Oncology Pharmacy Practice 2025; 31(7) doi: 10.1177/10781552251324896
80
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