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For: Liu C, Xiao GQ, Yan LN, Li B, Jiang L, Wen TF, Wang WT, Xu MQ, Yang JY. Value of α-fetoprotein in association with clinicopathological features of hepatocellular carcinoma. World J Gastroenterol 2013; 19(11): 1811-1819 [PMID: 23555170 DOI: 10.3748/wjg.v19.i11.1811]
URL: https://www.wjgnet.com/1007-9327/full/v19/i11/1811.htm
Number Citing Articles
1
Bo Hu, Xin-Ting Sang, Xiao-Bo Yang. Paraneoplastic leukemoid reaction in a patient with sarcomatoid hepatocellular carcinoma: A case report. World Journal of Clinical Cases 2019; 7(11): 1330-1336 doi: 10.12998/wjcc.v7.i11.1330
2
Lihong Shen, Lijia Shao, Shengchun Feng. Preoperative serum glutathione reductase activity and alpha-fetoprotein level are associated with early postoperative recurrence of hepatocellular carcinoma. Journal of Laboratory Medicine 2025; 49(1) doi: 10.1515/labmed-2024-0035
3
Chia-Jui Yen, Masatoshi Kudo, Ho-Yeong Lim, Chih-Hung Hsu, Arndt Vogel, Giovanni Brandi, Rebecca Cheng, Ioana Simona Nitu, Paolo Abada, Yanzhi Hsu, Andrew X. Zhu, Yoon-Koo Kang. Efficacy and Safety of Ramucirumab in Asian and Non-Asian Patients with Advanced Hepatocellular Carcinoma and Elevated Alpha-Fetoprotein: Pooled Individual Data Analysis of Two Randomized Studies. Liver Cancer 2020; 9(4) doi: 10.1159/000506946
4
Ziwei Guo, Jun Liang. Lipid-Based Factors: A Promising New Biomarker for Predicting Prognosis and Conditional Survival Probability in Hepatocellular Carcinoma. Journal of Hepatocellular Carcinoma 2022;  doi: 10.2147/JHC.S360871
5
Honglei Feng, Jiawei Xiao, Ze Li, Qian Wei, Bole Li, Li Ren. The prognostic value of protein induced by vitamin K absence or antagonist-II in hepatocellular carcinoma patients undergoing surgical resection. European Journal of Gastroenterology & Hepatology 2026; 38(4) doi: 10.1097/MEG.0000000000003130
6
Ines Dhifallah, Marwa Khedhiri, Anissa Chouikha, Ghassen Kharroubi, Walid Hammami, Amel Sadraoui, Mohamed Msaddek Azzouz, Nadia Maamouri, Tahar Khalfallah, Henda Triki, Pascal Pineau, Olfa Bahri. Hepatitis viruses take advantage of traditional practices to increase the burden of hepatocellular carcinoma in Tunisia. Archives of Virology 2020; 165(1) doi: 10.1007/s00705-019-04440-5
7
Hongbin Zhang, Siyuan Chai, Lintao Chen, Yubizhuo Wang, Yongna Cheng, Quan Fang, Guosen Wu, Xiangming Wang, Wenjie Liang, Wenbo Xiao. MRI Features of Hepatic Sarcomatoid Carcinoma Different From Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma. Frontiers in Oncology 2021; 11 doi: 10.3389/fonc.2021.611738
8
Lingzhan Meng, Hu Li, Yingjie Ji, Peng Yu, Zizheng Wang, Li Cao, Bin Shi, Yanling Shao, Jin Yan, Yinjie Gao, Zhenyu Zhu. Efficacy, safety, and biomarker analysis of TACE combined with lenvatinib plus sintilimab in unresectable hepatocellular carcinoma: a real-world study. Cancer Immunology, Immunotherapy 2024; 74(1) doi: 10.1007/s00262-024-03857-5
9
Rehan Ali, Yihe Yang, Mark Antkowiak, Ahmed Gabr, Ronald Mora, Nadine Abouchaleh, Ali Al Asadi, Laura Kulik, Daniel Ganger, Michael Abecassis, Nitin Kataraya, Mary Mulcahy, Al Benson, Devalingam Mahalingam, Bartley Thornburg, Samdeep Mouli, Robert J. Lewandowski, Riad Salem, Ahsun Riaz. Prognosticating Survival in Hepatocellular Carcinoma with Elevated Baseline Alpha-fetoprotein Treated with Radioembolization Using a Novel Laboratory Scoring System: Initial Development and Validation. CardioVascular and Interventional Radiology 2019; 42(5) doi: 10.1007/s00270-019-02191-z
10
V. B. Weeda, D. C. Aronson, J. Verheij, W. H. Lamers. Is hepatocellular carcinoma the same disease in children and adults? Comparison of histology, molecular background, and treatment in pediatric and adult patients. Pediatric Blood & Cancer 2019; 66(2) doi: 10.1002/pbc.27475
11
Yukai He, Yuan Hong, Gerald J Mizejewski. Engineering α-fetoprotein-based Gene Vaccines to Prevent and Treat Hepatocellular Carcinoma: Review and Future Prospects. Immunotherapy 2014; 6(6) doi: 10.2217/imt.14.46
12
ZiHao Ni, BoLin Wu, Zhao Liu, QiuCheng Wang, Xue Han, Wen Cheng, CunLi Guo. Clinical value of combined preoperative–postoperative neutrophil-to-lymphocyte ratio in predicting hepatocellular carcinoma prognosis after radiofrequency ablation. The British Journal of Radiology 2023; 96(1145) doi: 10.1259/bjr.20220887
13
Di Zhang, Qi Wei, Ge-Ge Wu, Xian-Ya Zhang, Wen-Wu Lu, Wen-Zhi Lv, Jin-Tang Liao, Xin-Wu Cui, Xue-Jun Ni, Christoph F. Dietrich. Preoperative Prediction of Microvascular Invasion in Patients With Hepatocellular Carcinoma Based on Radiomics Nomogram Using Contrast-Enhanced Ultrasound. Frontiers in Oncology 2021; 11 doi: 10.3389/fonc.2021.709339
14
Hiroji Shinkawa, Shogo Tanaka, Shigekazu Takemura, Ryosuke Amano, Kenjiro Kimura, Masahiko Kinoshita, Kanae Takahashi, Shuichiro Matsuzaki, Shoji Kubo. Nomograms predicting extra- and early intrahepatic recurrence after hepatic resection of hepatocellular carcinoma. Surgery 2021; 169(4) doi: 10.1016/j.surg.2020.10.012
15
Ashokachakkaravarthy Kandasamy, Biju Pottakkat. Alpha-fetoprotein: A molecular bootstrap for hepatocellular carcinoma. International Journal of Molecular and Immuno Oncology 2020; 5 doi: 10.25259/IJMIO_5_2020
16
HUAN-YU WANG, LIANG ZHANG, JIAN WU, ZI-JIAN ZHANG, BAO-GANG PENG, LI-JIAN LIANG, QI ZHOU. Adult hepatic cavernous hemangioma with highly elevated α-fetoprotein: A case report and review of the literature. Oncology Letters 2015; 9(2) doi: 10.3892/ol.2014.2769
17
Natalia Salinas Parra, Heather M. Ross, Adnan Khan, Marisa Wu, Risa Goldberg, Lokesh Shah, Sarah Mukhtar, Jacob Beiriger, Alexis Gerber, Dina Halegoua-DeMarzio. Advancements in the Diagnosis of Hepatocellular Carcinoma. International Journal of Translational Medicine 2023; 3(1) doi: 10.3390/ijtm3010005
18
Yuan Hong, Yibing Peng, Sheng Z. Guo, Jose Guevara-Patino, Junfeng Pang, Lisa H. Butterfield, Nahid F. Mivechi, David H. Munn, David L. Bartlett, Yukai He. Epitope-optimized alpha-fetoprotein genetic vaccines prevent carcinogen-induced murine autochthonous hepatocellular carcinoma. Hepatology 2014; 59(4) doi: 10.1002/hep.26893
19
Carla S. Coffin, Scott K. Fung, Fernando Alvarez, Curtis L. Cooper, Karen E. Doucette, Claire Fournier, Erin Kelly, Hin Hin Ko, Mang M Ma, Steven R Martin, Carla Osiowy, Alnoor Ramji, Edward Tam, Jean Pierre Villeneuve. Management of Hepatitis B Virus Infection: 2018 Guidelines from the Canadian Association for the Study of Liver Disease and Association of Medical Microbiology and Infectious Disease Canada. Canadian Liver Journal 2018; 1(4) doi: 10.3138/canlivj.2018-0008
20
Rui Gao, Chunli Cai, Jiancheng Gan, Xi Yang, Zeyu Shuang, Min Liu, Shengping Li, Hua Tang. miR-1236 down-regulates alpha-fetoprotein, thus causing PTEN accumulation, which inhibits the PI3K/Akt pathway and malignant phenotype in hepatoma cells. Oncotarget 2015; 6(8) doi: 10.18632/oncotarget.3338
21
Narongsak Rungsakulkij, Wikran Suragul, Somkit Mingphruedhi, Pongsatorn Tangtawee, Paramin Muangkaew, Suraida Aeesoa. Prognostic role of alpha-fetoprotein response after hepatocellular carcinoma resection. World Journal of Clinical Cases 2018; 6(6): 110-120 doi: 10.12998/wjcc.v6.i6.110
22
Ting Sun, Ruicen Li, Yiwen Qiu, Shu Shen, Wentao Wang. New Thresholds for AFP and Des-γ-Carboxy Prothrombin in Chronic Liver Disease Depending on the Use of Nucleoside Analogs and an Integrated Nomogram. International Journal of General Medicine 2021;  doi: 10.2147/IJGM.S335400
23
Tianying Ren, Xu Hou, Xin Zhang, Dongliang Chen, Juan Li, Yingnan Zhu, Zhiheng Liu, Dawei Yang. Validation of combined AFP, AFP-L3, and PIVKA II for diagnosis and monitoring of hepatocellular carcinoma in Chinese patients. Heliyon 2023; 9(11) doi: 10.1016/j.heliyon.2023.e21906
24
Tomohiko Sakabe, Junya Azumi, Yoshihisa Umekita, Kan Toriguchi, Etsuro Hatano, Yasuaki Hirooka, Goshi Shiota. Prognostic relevance of miR‐137 in patients with hepatocellular carcinoma. Liver International 2017; 37(2) doi: 10.1111/liv.13213
25
Shashi Bala Paul, Pabitra Sahu, Vishnubhatla Sreenivas, Neeti Nadda, Shivanand R. Gamanagatti, Baibaswata Nayak, S. Shalimar, Subrat K. Acharya. Prognostic role of serial alpha-fetoprotein levels in hepatocellular carcinoma treated with locoregional therapy. Scandinavian Journal of Gastroenterology 2019; 54(9) doi: 10.1080/00365521.2019.1660403
26
Yoh Zen, David Britton, Vikram Mitra, Andrew Brand, Stephan Jung, Christopher Loessner, Malcolm Ward, Ian Pike, Nigel Heaton, Alberto Quaglia. Protein expression profiles of chemo-resistant mixed phenotype liver tumors using laser microdissection and LC–MS/MS proteomics. EuPA Open Proteomics 2013; 1 doi: 10.1016/j.euprot.2013.10.001
27
Chyntia Olivia Maurine Jasirwan, Alessa Fahira, Lianda Siregar, Imelda Loho. The alpha-fetoprotein serum is still reliable as a biomarker for the surveillance of hepatocellular carcinoma in Indonesia. BMC Gastroenterology 2020; 20(1) doi: 10.1186/s12876-020-01365-1
28
Zhengwei Zha, Wenyue Wu, Qianqian Zhang, Xi Wang, Xuecan Mei, Yi Xiang, Derun Kong. Screening, clinical features and prognostic analysis of liver cirrhosis-related hepatocellular carcinoma. Scandinavian Journal of Gastroenterology 2021; 56(8) doi: 10.1080/00365521.2021.1938208
29
Zhan-Cheng Qiu, You-Wei Wu, Jun-Long Dai, Wei-Li Qi, Chu-Wen Chen, Yue-Qing Xu, Jun-Yi Shen, Chuan Li, Tian-Fu Wen. Tumor burden score combined with AFP and PIVKA-II (TAP score) to predict the prognosis of hepatocellular carcinoma patients after radical liver resection. Langenbeck's Archives of Surgery 2025; 410(1) doi: 10.1007/s00423-025-03650-7
30
Guanghua Liu, Fang Xia, Guoping Fan, Juming Yu, Lei Bao, Caiyuan Zhang, Runmin Chi, Tingting Zhang, Lijun Wang, Feng Shen, Dengbin Wang. Type 2 diabetes mellitus worsens the prognosis of intermediate-stage hepatocellular carcinoma after transarterial chemoembolization. Diabetes Research and Clinical Practice 2020; 169 doi: 10.1016/j.diabres.2020.108375
31
Min Luo, Fan Yang, Sheng-xin Huang, Zhi-peng Kuang, Xiao-ling Luo, Yuan-dong Li, Ji-ning Wu, Yu-an Xie. Two-Stage Model of Chemically Induced Hepatocellular Carcinoma in Mouse. Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics 2012; 20(11) doi: 10.3727/096504013X13747716581336
32
Marco Biolato, Giuseppe Marrone, Luca Miele, Antonio Gasbarrini, Antonio Grieco. Liver transplantation for intermediate hepatocellular carcinoma: An adaptive approach. World Journal of Gastroenterology 2017; 23(18): 3195-3204 doi: 10.3748/wjg.v23.i18.3195
33
Eun‐Ran Park, Sang‐Bum Kim, Jee‐San Lee, Yang‐Hyun Kim, Dong‐Hyoung Lee, Eung‐Ho Cho, Sun‐Hoo Park, Chul Ju Han, Bu‐Yeo Kim, Dong Wook Choi, Young Do Yoo, Ami Yu, Jae Won Lee, Ja June Jang, Young Nyun Park, Kyung‐Suk Suh, Kee‐Ho Lee. The mitochondrial hinge protein, UQCRH, is a novel prognostic factor for hepatocellular carcinoma. Cancer Medicine 2017; 6(4) doi: 10.1002/cam4.1042
34
Zhao-Dan Ye, Li Zhuang, Meng-Chen Song, Zhe Yang, Wu Zhang, Jing-Feng Zhang, Guo-Hong Cao. Drug-eluting bead transarterial chemoembolization as neoadjuvant therapy pre-liver transplantation for advanced-stage hepatocellular carcinoma. World Journal of Gastrointestinal Oncology 2024; 16(6): 2476-2486 doi: 10.4251/wjgo.v16.i6.2476
35
Merve Karayazili, Ulgen Celtik, Eda Ataseven, Deniz Nart, Orkan Ergun. Evaluation of surgical strategies and long-term outcomes in pediatric hepatocellular carcinoma. Pediatric Surgery International 2024; 40(1) doi: 10.1007/s00383-024-05721-0
36
WEY-RAN LIN, CHAO-WEI HSU, YI-CHENG CHEN, MING-LING CHANG, KUNG-HAO LIANG, YA-HUI HUANG, CHAU-TING YEH. GALNT14 genotype, α-fetoprotein and therapeutic side effects predict post-chemotherapy survival in patients with advanced hepatocellular carcinoma. Molecular and Clinical Oncology 2014; 2(4) doi: 10.3892/mco.2014.294
37
Darren W. Chua, Ye-Xin Koh, John C. Allen, Chung-Yip Chan, Ser-Yee Lee, Peng-Chung Cheow, Premaraj Jeyaraj, Jin-Yao Teo, Pierce K. Chow, Alexander Y. Chung, London L. Ooi, Brian K.P. Goh. Impact of spontaneous rupture on the survival outcomes after liver resection for hepatocellular carcinoma: A propensity matched analysis comparing ruptured versus non-ruptured tumors. European Journal of Surgical Oncology 2019; 45(9) doi: 10.1016/j.ejso.2019.03.044
38
Shuo Li, Ziyu He, Kai Zhou, Shuting Yang, Tong Zhou, Li Li, Song Li, Zhu Chen, Yuan Liu, Yan Deng. Electrochemical Sensors for Alpha-Fetoprotein Based Upon Poly(Lysine)-Titanium Dioxide-Black Phosphorus Composites. Analytical Letters 2026;  doi: 10.1080/00032719.2026.2733505
39
Lili Wang, Yanyan Zhang, Junfeng Li, Shunlin Guo, Jialiang Ren, Zhihao Li, Xin Zhuang, Jingmei Xue, Junqiang Lei. A Nomogram of Magnetic Resonance Imaging for Preoperative Assessment of Microvascular Invasion and Prognosis of Hepatocellular Carcinoma. Digestive Diseases and Sciences 2023; 68(12) doi: 10.1007/s10620-023-08022-z
40
Hana Hadi, Wan Muhammad Azfar Wan Shuaib, Raja Affendi Raja Ali, Hanita Othman. Utility of PIVKA-II and AFP in Differentiating Hepatocellular Carcinoma from Non-Malignant High-Risk Patients. Medicina 2022; 58(8) doi: 10.3390/medicina58081015
41
Amina Settar, Hassina Khaldoun, Dalila Tarzaali, Nacima Djennane, Chahrazed Makhlouf, Ichrak Selmani, Oularbi Yasmine, Khaldoune Amel. Lambda cyhalothrin and chlorantraniliprole caused biochemical, histological, and immunohistochemical alterations in male rabbit liver: Ameliorative effect of vitamins A, D, E, C mixture. Toxicology 2023; 487 doi: 10.1016/j.tox.2023.153464
42
Justin Y. Tang, Nitin Ohri, Rafi Kabarriti, Santiago Aparo, Jennifer Chuy, Sanjay Goel, Jonathan M. Schwartz, Milan Kinkhabwala, Andreas Kaubisch, Chandan Guha. Model for End-Stage Liver Disease and Sodium Velocity Predicts Overall Survival in Nonmetastatic Hepatocellular Carcinoma Patients. Canadian Journal of Gastroenterology and Hepatology 2018; 2018 doi: 10.1155/2018/5681979
43
Tsuyoshi Shimamura, Ryoichi Goto, Masaaki Watanabe, Norio Kawamura, Yasutsugu Takada. Liver Transplantation for Hepatocellular Carcinoma: How Should We Improve the Thresholds?. Cancers 2022; 14(2) doi: 10.3390/cancers14020419
44
Xu Liu, Jing Meng, Hongqin Xu, Junqi Niu. Alpha-fetoprotein to transaminase ratio is related to higher diagnostic efficacy for hepatocellular carcinoma. Medicine 2019; 98(17) doi: 10.1097/MD.0000000000015414
45
Xiaonan Mao, Yan Guo, Zaiming Lu, Feng Wen, Hongyuan Liang, Wei Sun. Enhanced CT Textures Derived From Computer Mathematic Distribution Analysis Enables Arterial Enhancement Fraction Being an Imaging Biomarker Option of Hepatocellular Carcinoma. Frontiers in Oncology 2020; 10 doi: 10.3389/fonc.2020.01337
46
Youwei Wu, Wei Peng, Junyi Shen, Xiaoyun Zhang, Chuan Li, Tianfu Wen. The impact of tumor burden at the initial hepatectomy on the recurrence-to-death survival after repeat surgical resection/radiofrequency ablation: a retrospective study. BMC Surgery 2022; 22(1) doi: 10.1186/s12893-022-01643-7
47
Gouling Zhan, Honghua Peng, Lehong Zhou, Long Jin, Xueyi Xie, Yu He, Xuan Wang, Zhangyan Du, Peiguo Cao. A web-based nomogram model for predicting the overall survival of hepatocellular carcinoma patients with external beam radiation therapy: A population study based on SEER database and a Chinese cohort. Frontiers in Endocrinology 2023; 14 doi: 10.3389/fendo.2023.1070396
48
Xinjun Lu, Shanshan Deng, Jiejie Xu, Benjamin L. Green, Honghua Zhang, Guofei Cui, Yi Zhou, Yi Zhang, Hongwei Xu, Fapeng Zhang, Rui Mao, Sheng Zhong, Thorsten Cramer, Matthias Evert, Diego F. Calvisi, Yukai He, Chao Liu, Xin Chen. Combination of AFP vaccine and immune checkpoint inhibitors slows hepatocellular carcinoma progression in preclinical models. Journal of Clinical Investigation 2023; 133(11) doi: 10.1172/JCI163291
49
Feng Ye, Di Ma, Xiao-Yong Gong, Yu-Chen Yang, Yong-Jun Chen. Development and validation of risk score for predicting spontaneous rupture of hepatocellular carcinoma. Annals of Surgical Treatment and Research 2020; 99(5) doi: 10.4174/astr.2020.99.5.268
50
Dong Ik Cha, Tae Wook Kang, Woo Kyoung Jeong, Jong Man Kim, Gyu-Seong Choi, Jae-Won Joh, Nam-Joon Yi, Soo Hyun Ahn. Preoperative assessment of microvascular invasion risk using gadoxetate-enhanced MRI for predicting outcomes after liver transplantation for single hepatocellular carcinoma within the Milan criteria. European Radiology 2023; 34(1) doi: 10.1007/s00330-023-09936-y
51
Nokjung Kim, Myung-Won You. Hepatocellular carcinoma and macrovascular tumor thrombosis: treatment outcomes and prognostic factors for survival. Japanese Journal of Radiology 2019; 37(11) doi: 10.1007/s11604-019-00868-6
52
Sevil Uygun Ilikhan, Muammer Bilici, Hatice Sahin, Ayşe Semra Demir Akca, Murat Can, Ibrahim Ilker Oz, Berrak Guven, M Cagatay Buyukuysal, Yucel Ustundag. Assessment of the correlation between serum prolidase and alpha-fetoprotein levels in patients with hepatocellular carcinoma. World Journal of Gastroenterology 2015; 21(22): 6999-7007 doi: 10.3748/wjg.v21.i22.6999
53
54
Hung-Wen Tsai, Chung-Liang Ho, Shu-Wen Cheng, Yih-Jyh Lin, Chou-Cheng Chen, Pin-Nan Cheng, Chia-Jui Yen, Ting-Tsung Chang, Po-Min Chiang, Shih-Huang Chan, Cheng-Hsun Ho, Shu-Hui Chen, Yi-Wen Wang, Nan-Haw Chow, Jou-Chun Lin. Progesterone receptor membrane component 1 as a potential prognostic biomarker for hepatocellular carcinoma. World Journal of Gastroenterology 2018; 24(10): 1152-1166 doi: 10.3748/wjg.v24.i10.1152
55
Guoyi Wu, Jing Wu, Xiaoben Pan, Bo Liu, Zhicheng Yao, Yuan Guo, Xiaolei Shi, Yitao Ding. Racial disparities in alpha‐fetoprotein testing and alpha‐fetoprotein status associated with the diagnosis and outcome of hepatocellular carcinoma patients. Cancer Medicine 2019; 8(15) doi: 10.1002/cam4.2549
56
Jeong-Ju Yoo, Goh Eun Chung, Jeong-Hoon Lee, Joon Yeul Nam, Young Chang, Jeong Min Lee, Dong Ho Lee, Hwi Young Kim, Eun Ju Cho, Su Jong Yu, Yoon Jun Kim, Jung-Hwan Yoon. Sub-classification of Advanced-Stage Hepatocellular Carcinoma: A Cohort Study Including 612 Patients Treated with Sorafenib. Cancer Research and Treatment 2018; 50(2) doi: 10.4143/crt.2017.126
57
Yi-Fei Li, Qiong-Qiong Hou, Shuang Zhao, Xiaoyan Chen, Min Tang, Lin Li. Identification of tumor-specific neoantigens and immune clusters of hepatocellular carcinoma for mRNA vaccine development. Journal of Cancer Research and Clinical Oncology 2023; 149(2) doi: 10.1007/s00432-022-04285-7
58
Min Du, Lingli Chen, Jing Zhao, Feng Tian, Haiying Zeng, Yunshan Tan, Huichuan Sun, Jian Zhou, Yuan Ji. Microvascular invasion (MVI) is a poorer prognostic predictor for small hepatocellular carcinoma. BMC Cancer 2014; 14(1) doi: 10.1186/1471-2407-14-38
59
ZiHao Ni, BoLin Wu, Meng Li, Xue Han, XiaoWen Hao, Yue Zhang, Wen Cheng, CunLi Guo. Prediction Model and Nomogram of Early Recurrence of Hepatocellular Carcinoma after Radiofrequency Ablation Based on Logistic Regression Analysis. Ultrasound in Medicine & Biology 2022; 48(9) doi: 10.1016/j.ultrasmedbio.2022.04.217
60
Camille Martenon Brodeur, Philippe Thibault, Mathieu Durand, Jean-Pierre Perreault, Martin Bisaillon. Dissecting the expression landscape of cytochromes P450 in hepatocellular carcinoma: towards novel molecular biomarkers. Genes & Cancer 2019; 10(3-4) doi: 10.18632/genesandcancer.190
61
S.S. Haque, Ravi Bhushan Raman, Mehboobus Salam. Liver Cancer - Genesis, Progression and Metastasis. 2023;  doi: 10.5772/intechopen.105856
62
A N L L Lalisang, W S Jeo, Y Moenadjat, T J M Lalisang. Correlation Between Serum Level of Alpha-Fetoprotein and Histological Differentiation Grade of Hepatocellular Carcinoma. Journal of Physics: Conference Series 2018; 1073 doi: 10.1088/1742-6596/1073/3/032056
63
Xiaojing Ren, Yuanyuan Ji, Xuhua Jiang, Xun Qi. Down-regulation of siglec-2 (CD22) predicts worse overall survival from HBV-related early-stage hepatocellular carcinoma: a preliminary analysis from Gene Expression Omnibus. Bioscience Reports 2018; 38(6) doi: 10.1042/BSR20181423
64
Md Najmul Haque, Mst Rupali Yasmin, Md Mafiur Rahman, Md Ashraful Alom. Association of Serum Alpha-fetoprotein with BCLC and TNM Staging of Hepatocellular Carcinoma to Assess its Resectability. TAJ: Journal of Teachers Association 2026; 39(3) doi: 10.70818/taj.v39i03.0811
65
Richa Surit, Ravi Shekhar, Dinesh Kumar Sinha, Sanjeet Kumar Singh, Uday Kumar, Nidhi Prasad. Hepatitis B in hepatocellular carcinoma patients and its correlation with alpha-fetoprotein and liver enzymes. Journal of Cancer Research and Therapeutics 2022; 18(4) doi: 10.4103/jcrt.JCRT_239_19
66
Samir F. Zohny, Ahlam H. Mahmoud, Ibrahim H. Borai, Faten S. Bayoumi, Eman Eissa. Chemopreventive and therapeutic efficacy of Salsola inermis extract against N-nitrosodiethylamine-initiated and phenobarbital-promoted hepatocellular carcinogenesis in Wistar rats. Biomedicine & Aging Pathology 2013; 3(4) doi: 10.1016/j.biomag.2013.08.002
67
Sih‐Han Liao, Tung‐Hung Su, Yung‐Ming Jeng, Po‐Chin Liang, Ding‐Shinn Chen, Chien‐Hung Chen, Jia‐Horng Kao. Clinical Manifestations and Outcomes of Patients with Sarcomatoid Hepatocellular Carcinoma. Hepatology 2019; 69(1) doi: 10.1002/hep.30162
68
Andrea Notarpaolo, Richard Layese, Paolo Magistri, Maria Gambato, Michele Colledan, Giulia Magini, Lucia Miglioresi, Alessandro Vitale, Giovanni Vennarecci, Cecilia D Ambrosio, Patrizia Burra, Fabrizio Di Benedetto, Stefano Fagiuoli, Marco Colasanti, Giuseppe Maria Ettorre, Arnoldo Andreoli, Umberto Cillo, Alexis Laurent, Sandrine Katsahian, Etienne Audureau, Françoise Roudot-Thoraval, Christophe Duvoux. Validation of the AFP model as a predictor of HCC recurrence in patients with viral hepatitis-related cirrhosis who had received a liver transplant for HCC. Journal of Hepatology 2017; 66(3) doi: 10.1016/j.jhep.2016.10.038
69
Lele Miao, Zhengchao Zhang, Zhijian Ren, Yumin Li. Application of Immunotherapy in Hepatocellular Carcinoma. Frontiers in Oncology 2021; 11 doi: 10.3389/fonc.2021.699060
70
Mohammed El Fayoumie, Mahmoud Abdelhady, Ahmed Gawish, Usama Hantour, Ismail Abdelkhaleek, Mohamed Abdelraheem, Alaa Alsawak, Ahmed Alwassief, Ashraf Elbahrawy. Changing Patterns of Hepatocellular Carcinoma after Treatment with Direct Antiviral Agents. Gastrointestinal Tumors 2020; 7(1-2) doi: 10.1159/000505326
71
Hayet Aouragh, Hayat Ait Kaci, Imene Haroun, Safia Zenia, Lynda Abdellaoui, Nadjet Amina Khelifi Touhami, Nassim Ouchene, Dalila Tarzaali, Kamel Bentabak, Leila Saadi. Gender-Related Differences in Clinical and Pathological Characteristics of Algerian Pa-tients with Hepatocellular Carcinoma: A 22 Year Retrospective Study. Iranian South Medical Journal 2025; 28(2) doi: 10.66224/ismj.28.2.611
72
Shumin Li, Qianwen Zeng, Ruiming Liang, Jianyan Long, Yihao Liu, Han Xiao, Kaiyu Sun. Using Systemic Inflammatory Markers to Predict Microvascular Invasion Before Surgery in Patients With Hepatocellular Carcinoma. Frontiers in Surgery 2022; 9 doi: 10.3389/fsurg.2022.833779
73
Ahsun Riaz, Riad Salem. Laboratory and Imaging Prognostic Indicators following Arterial Locoregional Therapies for Hepatocellular Carcinoma Survival. Journal of Vascular and Interventional Radiology 2019; 30(12) doi: 10.1016/j.jvir.2019.09.003
74
Cheon-Soo Park, Yong-Kyu Chung, Sung-Hwa Kang, Shin Hwang. Diagnostic predictability of hepatocellular carcinoma tumor markers in patients waiting for living donor liver transplantation. Annals of Liver Transplantation 2022; 2(1) doi: 10.52604/alt.22.0012
75
Nurbubu T. Moldogazieva, Daria S. Ostroverkhova, Nikolai N. Kuzmich, Vladimir V. Kadochnikov, Alexander A. Terentiev, Yuri B. Porozov. Elucidating Binding Sites and Affinities of ERα Agonists and Antagonists to Human Alpha-Fetoprotein by In Silico Modeling and Point Mutagenesis. International Journal of Molecular Sciences 2020; 21(3) doi: 10.3390/ijms21030893
76
Jing‐Houng Wang, Kwong‐Ming Kee, Chih‐Yun Lin, Chao‐Hung Hung, Chien‐Hung Chen, Chuan‐Mo Lee, Sheng‐Nan Lu. Validation and modification of a proposed substaging system for patients with intermediate hepatocellular carcinoma. Journal of Gastroenterology and Hepatology 2015; 30(2) doi: 10.1111/jgh.12686
77
Haruki Kimura, Kazuyoshi Ohkawa, Masanori Miyazaki, Mitsuru Sakakibara, Kazuho Imanaka, Takeshi Tamura, Hironari Sueyoshi, Ryoji Takada, Nobuyasu Fukutake, Hiroyuki Uehara, Reiko Ashida, Tatsuya Ioka, Tetsuro Nakazawa, Katsuyuki Nakanishi, Kazuhiro Katayama. Subclassification of patients with intermediate-stage (Barcelona Clinic Liver Cancer stage-B) hepatocellular carcinoma using the up-to-seven criteria and serum tumor markers. Hepatology International 2017; 11(1) doi: 10.1007/s12072-016-9771-0
78
Gui-Min Hou, Hai-ling Liu, Hong Wu, Yong Zeng. Prediction of Prognosis for cHCC-CC Patients After Surgery: Comparison of Tumor Marker Score Based on AFP, CEA, CA19-9, and Other Clinical Stages. Annals of Surgical Oncology 2021; 28(12) doi: 10.1245/s10434-021-09949-1
79
Mingjie Yao, Jingmin Zhao, Fengmin Lu. Alpha-fetoprotein still is a valuable diagnostic and prognosis predicting biomarker in hepatitis B virus infection-related hepatocellular carcinoma. Oncotarget 2016; 7(4) doi: 10.18632/oncotarget.6913
80
Mohamed Bouattour, Audrey Payancé, Johanna Wassermann. Evaluation of antiangiogenic efficacy in advanced hepatocellular carcinoma: Biomarkers and functional imaging. World Journal of Hepatology 2015; 7(20): 2245-2263 doi: 10.4254/wjh.v7.i20.2245
81
Maria J Citores, Jose L Lucena, Sara de la Fuente, Valentin Cuervas-Mons. Serum biomarkers and risk of hepatocellular carcinoma recurrence after liver transplantation. World Journal of Hepatology 2019; 11(1): 50-64 doi: 10.4254/wjh.v11.i1.50
82
Sunyoung Lee, Tae Wook Kang, Kyoung Doo Song, Min Woo Lee, Hyunchul Rhim, Hyo Keun Lim, So Yeon Kim, Dong Hyun Sinn, Jong Man Kim, Kyunga Kim, Sang Yun Ha. Effect of Microvascular Invasion Risk on Early Recurrence of Hepatocellular Carcinoma After Surgery and Radiofrequency Ablation. Annals of Surgery 2021; 273(3) doi: 10.1097/SLA.0000000000003268
83
Yeonjung Ha, Ju Hyun Shim, Seon‐Ok Kim, Kang Mo Kim, Young‐Suk Lim, Han Chu Lee. Clinical appraisal of the recently proposed Barcelona Clinic Liver Cancer stage B subclassification by survival analysis. Journal of Gastroenterology and Hepatology 2014; 29(4) doi: 10.1111/jgh.12452
84
Jayaprakash Kubalady Shetty, Hosapatna Laxminarayan Kishan Prasad, Abena Hidangmayum. The Spectrum of Histopathological Lesions Presenting as a Hepatic Nodule and Their Relationship With Serum Alpha-Fetoprotein Level. Journal of Health and Allied Sciences NU 2026; 0 doi: 10.25259/JHASNU_242_2025
85
Kazunari Sasaki, Masamichi Matsuda, Yu Ohkura, Yusuke Kawamura, Masafumi Inoue, Masaji Hashimoto, Kenji Ikeda, Hiromitsu Kumada, Goro Watanabe. Implication of an extremely high preoperative alpha-fetoprotein value (>4,000 ng/mL) for the long-term outcomes of hepatectomy for resectable hepatocellular carcinoma. Surgery 2015; 157(2) doi: 10.1016/j.surg.2014.09.010
86
Ting Wang, Kun-He Zhang. New Blood Biomarkers for the Diagnosis of AFP-Negative Hepatocellular Carcinoma. Frontiers in Oncology 2020; 10 doi: 10.3389/fonc.2020.01316
87
Association of Serum Alpha-Fetoprotein with BCLC And TNM Staging Of Hepatocellular Carcinoma to Assess its Resectability. TAJ: Journal of Teachers Association 2026; 39(2) doi: 10.70818/taj.v39i2.0702
88
Sylene C.R. Carvalho, Luydson R.S. Vasconcelos, Leonardo da Fonseca, Rodrigo F. Carmo, Michele T. Tomitão, Dayse C.B.L. Aroucha, Leila M.M.B. Pereira, José Tadeu Stefano, Ulysses Ribeiro-Júnior, Claudia P. Oliveira, Flair J. Carrilho. Methylene tetrahydrofolate reductase (MTHFR) and vascular endothelial growth factor (VEGF) polymorphisms in Brazilian patients with Hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC). Clinics 2021; 76 doi: 10.6061/clinics/2021/e2881
89
So Hyun Park, Bohyun Kim, Sehee Kim, Suyoung Park, Yeon Ho Park, Seung Kak Shin, Pil Soo Sung, Joon-Il Choi. Estimating postsurgical outcomes of patients with a single hepatocellular carcinoma using gadoxetic acid–enhanced MRI: risk scoring system development and validation. European Radiology 2023; 33(5) doi: 10.1007/s00330-023-09539-7
90
Yang-Xun Pan, Xu-Qi Sun, Zi-Li Hu, Wa Xie, Ke-Xin Nie, Ai-Ping Fang, Ying-Yao Zhang, Yi-Zhen Fu, Jin-Bin Chen, Jun-Cheng Wang, Xin Wang, Yao-Jun Zhang, Dan-Dan Hu, Min-Shan Chen. Prognostic Values of Alpha-Fetoprotein and Des-Gamma-Carboxyprothrombin in Hepatocellular Carcinoma in China: An Analysis of 4792 Patients. Journal of Hepatocellular Carcinoma 2021;  doi: 10.2147/JHC.S316223
91
Christopher Welberry, Isabel Macdonald, Jane McElveen, Celine Parsy-Kowalska, Jared Allen, Graham Healey, William Irving, Andrea Murray, Caroline Chapman, Vasilis Kosmoliaptsis. Tumor-associated autoantibodies in combination with alpha-fetoprotein for detection of early stage hepatocellular carcinoma. PLOS ONE 2020; 15(5) doi: 10.1371/journal.pone.0232247
92
Juncheng Wang, Yize Mao, Yongcheng Liu, Zhenxin Chen, Minshan Chen, Xiangming Lao, Shengping Li. Hepatocellular Carcinoma in Children and Adolescents: Clinical Characteristics and Treatment. Journal of Gastrointestinal Surgery 2017; 21(7) doi: 10.1007/s11605-017-3420-3
93
Dongna Xie, Shengnan Jia, Nian Wang, Lianghai Hu. . Advances in Clinical Chemistry 2026; 132 doi: 10.1016/bs.acc.2026.01.001
94
Serkan Sucu, Brian Longbottom, Hassan Aziz. When Explant Surprises: Management and Outcomes of Hepatocellular Carcinoma Beyond Milan Criteria Discovered Post‐Transplant‐ A Narrative Review of Literature. Journal of Surgical Oncology 2026;  doi: 10.1002/jso.70380
95
Renxiang Xia, Jing Peng, Jian He, Ping Jiang, Chunyan Yuan, Xiaoli Liu, Yunqing Yao. The Serious Challenge of Occult Hepatitis B Virus Infection-Related Hepatocellular Carcinoma in China. Frontiers in Microbiology 2022; 13 doi: 10.3389/fmicb.2022.840825
96
Haiqing Wang, Lunan Yan. Operative Techniques in Liver Resection. 2016;  doi: 10.1007/978-94-017-7411-6_11
97
Bérénice Charrière, Charlotte Maulat, Bertrand Suc, Fabrice Muscari. Contribution of alpha-fetoprotein in liver transplantation for hepatocellular carcinoma. World Journal of Hepatology 2016; 8(21): 881-890 doi: 10.4254/wjh.v8.i21.881
98
Zachary J. Brown, Bernd Heinrich, Tim F. Greten. Mouse models of hepatocellular carcinoma: an overview and highlights for immunotherapy research. Nature Reviews Gastroenterology & Hepatology 2018; 15(9) doi: 10.1038/s41575-018-0033-6
99
Jun-yi Shen, Chuan Li, Tian-fu Wen, Lv-nan Yan, Bo Li, Wen-tao Wang, Jia-yin Yang, Ming-qing Xu. Alpha fetoprotein changes predict hepatocellular carcinoma survival beyond the Milan criteria after hepatectomy. Journal of Surgical Research 2017; 209 doi: 10.1016/j.jss.2016.10.005
100
Rawaa AlChalabi, Mustafa S. AL-Salmani, Semaa A. Shaban, Ahmed AbdulJabbar Suleiman. Role of Dysregulated Immune Biomarkers in Hepatocellular Carcinoma Metastasis: A Systematic Meta-Analysis Review. South Asian Journal of Cancer 2025; 14(02) doi: 10.1055/s-0044-1789589
101
CHENG-ZUO XIAO, WEI WEI, ZHI-XING GUO, SHU-HONG LI, YONG-FA ZHANG, JIA-HONG WANG, MING SHI, RONG-PING GUO. A prognosis model for patients with hepatocellular carcinoma and portal vein tumor thrombus following hepatic resection. Oncology Letters 2015; 10(5) doi: 10.3892/ol.2015.3677
102
Dae Geon Ahn, Hyung Joon Kim, Hyun Kang, Hyun Woong Lee, Si Hyun Bae, Joon Hyoek Lee, Yong Han Paik, June Sung Lee. Feasibility of α-fetoprotein as a diagnostic tool for hepatocellular carcinoma in Korea. The Korean Journal of Internal Medicine 2015; 31(1) doi: 10.3904/kjim.2016.31.1.46
103
Xiaohong Ma, Jingwei Wei, Dongsheng Gu, Yongjian Zhu, Bing Feng, Meng Liang, Shuang Wang, Xinming Zhao, Jie Tian. Preoperative radiomics nomogram for microvascular invasion prediction in hepatocellular carcinoma using contrast-enhanced CT. European Radiology 2019; 29(7) doi: 10.1007/s00330-018-5985-y
104
Chloé Sauzay, Alexandra Petit, Anne-Marie Bourgeois, Jean-Claude Barbare, Bruno Chauffert, Antoine Galmiche, Aline Houessinon. Alpha-foetoprotein (AFP): A multi-purpose marker in hepatocellular carcinoma. Clinica Chimica Acta 2016; 463 doi: 10.1016/j.cca.2016.10.006